Tofacitinib: An Option for Acute Severe Ulcerative Colitis?

Detalhes bibliográficos
Autor(a) principal: Santos,Sara
Data de Publicação: 2022
Outros Autores: Gamelas,Verónica, Saraiva,Rita, Simões,Guilherme, Saiote,Joana, Ramos,Jaime
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056
Resumo: Abstract Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the need for new drugs and data on their efficacy and safety. We describe 2 cases of acute episodes in which tofacitinib was used as a rescue therapy.
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spelling Tofacitinib: An Option for Acute Severe Ulcerative Colitis?Acute severe ulcerative colitisTofacitinibAbstract Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the need for new drugs and data on their efficacy and safety. We describe 2 cases of acute episodes in which tofacitinib was used as a rescue therapy.Sociedade Portuguesa de Gastrenterologia2022-04-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056GE-Portuguese Journal of Gastroenterology v.29 n.2 2022reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056Santos,SaraGamelas,VerónicaSaraiva,RitaSimões,GuilhermeSaiote,JoanaRamos,Jaimeinfo:eu-repo/semantics/openAccess2024-02-06T17:34:18Zoai:scielo:S2341-45452022000200056Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:36:17.540403Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
spellingShingle Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
Santos,Sara
Acute severe ulcerative colitis
Tofacitinib
title_short Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title_full Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title_fullStr Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title_full_unstemmed Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
title_sort Tofacitinib: An Option for Acute Severe Ulcerative Colitis?
author Santos,Sara
author_facet Santos,Sara
Gamelas,Verónica
Saraiva,Rita
Simões,Guilherme
Saiote,Joana
Ramos,Jaime
author_role author
author2 Gamelas,Verónica
Saraiva,Rita
Simões,Guilherme
Saiote,Joana
Ramos,Jaime
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Santos,Sara
Gamelas,Verónica
Saraiva,Rita
Simões,Guilherme
Saiote,Joana
Ramos,Jaime
dc.subject.por.fl_str_mv Acute severe ulcerative colitis
Tofacitinib
topic Acute severe ulcerative colitis
Tofacitinib
description Abstract Tofacitinib has emerged as a new option for ulcerative colitis. Its rapid absorption, metabolism, and clinical improvement make it an interesting option for rescue therapy in acute severe ulcerative colitis (ASUC), a situation with limited therapeutic options in patients with a long-term disease course and multiple drug failure. The management of ASUC in this setting becomes challenging, underlying the need for new drugs and data on their efficacy and safety. We describe 2 cases of acute episodes in which tofacitinib was used as a rescue therapy.
publishDate 2022
dc.date.none.fl_str_mv 2022-04-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/report
format report
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056
url http://scielo.pt/scielo.php?script=sci_arttext&pid=S2341-45452022000200056
dc.language.iso.fl_str_mv eng
language eng
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
publisher.none.fl_str_mv Sociedade Portuguesa de Gastrenterologia
dc.source.none.fl_str_mv GE-Portuguese Journal of Gastroenterology v.29 n.2 2022
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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