Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy

Detalhes bibliográficos
Autor(a) principal: Fonseca, Filipa Ribeiro da
Data de Publicação: 2019
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/130074
Resumo: Dissertation presented to obtain the Master degree in Biochemistry for Health
id RCAP_7084ef2db3e8cbcc3e51f3e775d0ac75
oai_identifier_str oai:run.unl.pt:10362/130074
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapyClosed-loop delivery systemGlucagon like peptide-1 analoguesglucose-oxidasepH-sensitive nanoparticlesDissertation presented to obtain the Master degree in Biochemistry for Health"Type 2 diabetes mellitus (T2DM) is one of the biggest health problems in the world. Glucagon like peptide-1, an endogenous gastrointestinal incretin hormone that stimulates insulin secretion, is considered an attractive therapeutic agent for T2DM treatment. Nevertheless, its short half-life has led to the development of longer half-life GLP-1 analogues, as exenatide. Still, current dosage forms for exenatide delivery are not exempt of shortcomings. Nanotechnology-based systems may offer several advantages over conventional dosage forms for drug delivery.(...)"Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António XavierRUNFonseca, Filipa Ribeiro da2022-01-02T02:02:08Z2019-092019-09-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10362/130074enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:08:53Zoai:run.unl.pt:10362/130074Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:46:41.603315Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy
title Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy
spellingShingle Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy
Fonseca, Filipa Ribeiro da
Closed-loop delivery system
Glucagon like peptide-1 analogues
glucose-oxidase
pH-sensitive nanoparticles
title_short Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy
title_full Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy
title_fullStr Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy
title_full_unstemmed Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy
title_sort Establishment of bioengineered glucose-responsive nanoparticles for type 2 diabetes mellitus therapy
author Fonseca, Filipa Ribeiro da
author_facet Fonseca, Filipa Ribeiro da
author_role author
dc.contributor.none.fl_str_mv RUN
dc.contributor.author.fl_str_mv Fonseca, Filipa Ribeiro da
dc.subject.por.fl_str_mv Closed-loop delivery system
Glucagon like peptide-1 analogues
glucose-oxidase
pH-sensitive nanoparticles
topic Closed-loop delivery system
Glucagon like peptide-1 analogues
glucose-oxidase
pH-sensitive nanoparticles
description Dissertation presented to obtain the Master degree in Biochemistry for Health
publishDate 2019
dc.date.none.fl_str_mv 2019-09
2019-09-01T00:00:00Z
2022-01-02T02:02:08Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/130074
url http://hdl.handle.net/10362/130074
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier
publisher.none.fl_str_mv Universidade Nova de Lisboa. Instituto de Tecnologia Química e Biológica António Xavier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799138070097821696

Registros relacionados