New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical Dermatology
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://doi.org/10.29021/spdv.76.4.972 |
Resumo: | Cutaneous leishmaniasis may mimic other infections in overlapping endemic areas and timely treatment prevents dissemination of the parasite. The required histopathological and microbiological examinations are not always available, and can only give a deferred confirmation of the diagnosis. In contrast, reflectance confocal microscopy (RCM) allows real-time visualization till the level of papillary dermis. A 59-year-old Brazilian male presented with ulcerated plaques and tumors on the extremities. The clinical differential diagnosis included leishmaniasis and other infections with lymphocutaneous pattern of dissemination. RCM showed the characteristic picture of «eggs in a bird’s nest» which has been described in cutaneous leishmaniasis. The diagnosis of leishmaniasis was later confirmed by skin biopsy, in which Leishmania guyanensis was identified by parasitological examination. After treatment with liposomal amphotericin B, reassessment with RCM corroborated the clinical cure, showing an «empty nest» picture. In conclusion, RCM noninvasively provides useful information for diagnosis and follow-up of cutaneous leishmaniasis. |
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New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical DermatologyDermoscopyLeishmaniaLeishmaniasisCutaneous/diagnosisMicroscopyConfocalCutaneous leishmaniasis may mimic other infections in overlapping endemic areas and timely treatment prevents dissemination of the parasite. The required histopathological and microbiological examinations are not always available, and can only give a deferred confirmation of the diagnosis. In contrast, reflectance confocal microscopy (RCM) allows real-time visualization till the level of papillary dermis. A 59-year-old Brazilian male presented with ulcerated plaques and tumors on the extremities. The clinical differential diagnosis included leishmaniasis and other infections with lymphocutaneous pattern of dissemination. RCM showed the characteristic picture of «eggs in a bird’s nest» which has been described in cutaneous leishmaniasis. The diagnosis of leishmaniasis was later confirmed by skin biopsy, in which Leishmania guyanensis was identified by parasitological examination. After treatment with liposomal amphotericin B, reassessment with RCM corroborated the clinical cure, showing an «empty nest» picture. In conclusion, RCM noninvasively provides useful information for diagnosis and follow-up of cutaneous leishmaniasis.Sociedade Portuguesa de Dermatologia e Venereologia2018-12-27T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfimage/pngimage/pngimage/pngimage/pnghttps://doi.org/10.29021/spdv.76.4.972oai:ojs.revista.spdv.com.pt:article/972Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 4 (2018): October - December; 445-450Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 4 (2018): Outubro - Dezembro; 445-4502182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://revista.spdv.com.pt/index.php/spdv/article/view/972https://doi.org/10.29021/spdv.76.4.972https://revista.spdv.com.pt/index.php/spdv/article/view/972/609https://revista.spdv.com.pt/index.php/spdv/article/view/972/768https://revista.spdv.com.pt/index.php/spdv/article/view/972/769https://revista.spdv.com.pt/index.php/spdv/article/view/972/770https://revista.spdv.com.pt/index.php/spdv/article/view/972/771Ortins-Pina, AnaSoares-de-Almeida, LuísFilipe, PauloOliveira, André Laureanoinfo:eu-repo/semantics/openAccess2022-10-06T12:35:09Zoai:ojs.revista.spdv.com.pt:article/972Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:08.250723Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical Dermatology |
title |
New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical Dermatology |
spellingShingle |
New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical Dermatology Ortins-Pina, Ana Dermoscopy Leishmania Leishmaniasis Cutaneous/diagnosis Microscopy Confocal |
title_short |
New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical Dermatology |
title_full |
New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical Dermatology |
title_fullStr |
New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical Dermatology |
title_full_unstemmed |
New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical Dermatology |
title_sort |
New World Leishmaniasis: The Role of Confocal Microscopy in Diagnosis and Follow-up - Tropical Dermatology |
author |
Ortins-Pina, Ana |
author_facet |
Ortins-Pina, Ana Soares-de-Almeida, Luís Filipe, Paulo Oliveira, André Laureano |
author_role |
author |
author2 |
Soares-de-Almeida, Luís Filipe, Paulo Oliveira, André Laureano |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Ortins-Pina, Ana Soares-de-Almeida, Luís Filipe, Paulo Oliveira, André Laureano |
dc.subject.por.fl_str_mv |
Dermoscopy Leishmania Leishmaniasis Cutaneous/diagnosis Microscopy Confocal |
topic |
Dermoscopy Leishmania Leishmaniasis Cutaneous/diagnosis Microscopy Confocal |
description |
Cutaneous leishmaniasis may mimic other infections in overlapping endemic areas and timely treatment prevents dissemination of the parasite. The required histopathological and microbiological examinations are not always available, and can only give a deferred confirmation of the diagnosis. In contrast, reflectance confocal microscopy (RCM) allows real-time visualization till the level of papillary dermis. A 59-year-old Brazilian male presented with ulcerated plaques and tumors on the extremities. The clinical differential diagnosis included leishmaniasis and other infections with lymphocutaneous pattern of dissemination. RCM showed the characteristic picture of «eggs in a bird’s nest» which has been described in cutaneous leishmaniasis. The diagnosis of leishmaniasis was later confirmed by skin biopsy, in which Leishmania guyanensis was identified by parasitological examination. After treatment with liposomal amphotericin B, reassessment with RCM corroborated the clinical cure, showing an «empty nest» picture. In conclusion, RCM noninvasively provides useful information for diagnosis and follow-up of cutaneous leishmaniasis. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12-27T00:00:00Z |
dc.type.driver.fl_str_mv |
journal article info:eu-repo/semantics/article |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://doi.org/10.29021/spdv.76.4.972 oai:ojs.revista.spdv.com.pt:article/972 |
url |
https://doi.org/10.29021/spdv.76.4.972 |
identifier_str_mv |
oai:ojs.revista.spdv.com.pt:article/972 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://revista.spdv.com.pt/index.php/spdv/article/view/972 https://doi.org/10.29021/spdv.76.4.972 https://revista.spdv.com.pt/index.php/spdv/article/view/972/609 https://revista.spdv.com.pt/index.php/spdv/article/view/972/768 https://revista.spdv.com.pt/index.php/spdv/article/view/972/769 https://revista.spdv.com.pt/index.php/spdv/article/view/972/770 https://revista.spdv.com.pt/index.php/spdv/article/view/972/771 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf image/png image/png image/png image/png |
dc.publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
publisher.none.fl_str_mv |
Sociedade Portuguesa de Dermatologia e Venereologia |
dc.source.none.fl_str_mv |
Journal of the Portuguese Society of Dermatology and Venereology; Vol 76 No 4 (2018): October - December; 445-450 Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 76 n. 4 (2018): Outubro - Dezembro; 445-450 2182-2409 2182-2395 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799130567476772864 |