IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERY

Detalhes bibliográficos
Autor(a) principal: Valentim, Maria
Data de Publicação: 2022
Outros Autores: Silva, Patrícia, Pereira, Ana, Vilaça, Sónia, Costa, Catarina, Martins, Sandra F.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.34635/rpc.942
Resumo: Periampullary cancers are located up to a maximum distance of 2 cm from the duodenal papilla, with pancreatic cancer being the most common. Despite advances in surgical technique, survival rates remain low, making it essential to identify prognostic factors. Visceral obesity has been identified as a risk factor for cancer development, but its influence on the morbidity and mortality of operated patients remains controversial. This study aims to identify an association between the presence of preoperative visceral obesity and an increased risk of postoperative morbimortality in patients with periampullary cancers at Hospital de Braga. The sample includes 44 patients with periampullary cancers who underwent surgery with a curative intention between January/2011 and April/2018. The area of visceral fat was measured using the ImageJ software. Statistical analysis was performed using the SPSS software version 25. Visceral fat was not implicated in longer hospital stay or postoperative complications. The survival analysis showed no differences in disease-free survival at 1 year (p = 0.121) and 5 years (p = 0.222) or in overall survival at 1 year (p = 0.163) and 5 years (p = 0.053) between groups. Our data suggest that preoperative visceral obesity is not a risk factor for greater postoperative morbidity and mortality in individuals with periampullary cancers. Despite the reduced sample, this study evaluates visceral obesity in four types of tumors with many similar characteristics. Additional studies with larger samples are needed to confirm our observations.
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spelling IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERYIMPACTO DA GORDURA VISCERAL NO PROGNÓSTICO DA CIRURGIA DO CANCRO PERI-AMPOLARPeriampullary cancers are located up to a maximum distance of 2 cm from the duodenal papilla, with pancreatic cancer being the most common. Despite advances in surgical technique, survival rates remain low, making it essential to identify prognostic factors. Visceral obesity has been identified as a risk factor for cancer development, but its influence on the morbidity and mortality of operated patients remains controversial. This study aims to identify an association between the presence of preoperative visceral obesity and an increased risk of postoperative morbimortality in patients with periampullary cancers at Hospital de Braga. The sample includes 44 patients with periampullary cancers who underwent surgery with a curative intention between January/2011 and April/2018. The area of visceral fat was measured using the ImageJ software. Statistical analysis was performed using the SPSS software version 25. Visceral fat was not implicated in longer hospital stay or postoperative complications. The survival analysis showed no differences in disease-free survival at 1 year (p = 0.121) and 5 years (p = 0.222) or in overall survival at 1 year (p = 0.163) and 5 years (p = 0.053) between groups. Our data suggest that preoperative visceral obesity is not a risk factor for greater postoperative morbidity and mortality in individuals with periampullary cancers. Despite the reduced sample, this study evaluates visceral obesity in four types of tumors with many similar characteristics. Additional studies with larger samples are needed to confirm our observations.Os tumores periampulares estão localizados a uma distância máxima de 2 cm da papila duodenal, sendo a neoplasia mais comum do pâncreas. Apesar dos avanços da técnica cirúrgica, as taxas de sobrevivência permanecem baixas, sendo fundamental a identificação de fatores determinantes do prognóstico. A obesidade visceral tem sido identificada como fator de risco para o desenvolvimento do cancro, mas a sua influência na morbimortalidade pós-operatória permanece controversa. Este estudo teve como objetivo explorar a associação entre a presença de obesidade visceral pré-operatória e o risco de morbimortalidade pós-operatória em indivíduos com cancro periampular no Hospital de Braga. A amostra é constituída por 44 indivíduos com  cancro periampular, submetidos a cirurgia com intenção curativa, entre janeiro de 2011 e abril de 2018. A área de gordura visceral foi medida com recurso ao software ImageJ. A análise estatística foi realizada com o software SPSS versão 25. A gordura visceral não se associou ao maior tempo de internamento ou complicações pós-operatórias. A análise de sobrevivência não revelou diferenças no tempo livre de doença a 1 ano (p = 0,121) ou a 5 anos (p = 0,222), nem na sobrevida global a 1 ano (p = 0,163) ou a 5 anos (p = 0,053) entre os grupos. Os dados sugerem que a obesidade visceral pré-operatória não é fator de risco para maior morbimortalidade pós-operatória em indivíduos com cancro periampular. Apesar da amostra reduzida, este estudo avalia a obesidade visceral em quatro tipos de tumores com muitas características semelhantes. Estudos adicionais com amostras maiores são necessários para confirmar as nossas observações.Sociedade Portuguesa de Cirurgia2022-02-02info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.34635/rpc.942https://doi.org/10.34635/rpc.942Revista Portuguesa de Cirurgia; No 51 (2021): Number 51 - October 2021; 45-52Revista Portuguesa de Cirurgia; No 51 (2021): Number 51 - October 2021; 45-522183-11651646-6918reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://revista.spcir.com/index.php/spcir/article/view/942https://revista.spcir.com/index.php/spcir/article/view/942/618Copyright (c) 2021 Revista Portuguesa de Cirurgiainfo:eu-repo/semantics/openAccessValentim, MariaSilva, PatríciaPereira, AnaVilaça, SóniaCosta, CatarinaMartins, Sandra F.2024-03-14T22:04:53Zoai:revista.spcir.com:article/942Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T04:00:45.372115Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERY
IMPACTO DA GORDURA VISCERAL NO PROGNÓSTICO DA CIRURGIA DO CANCRO PERI-AMPOLAR
title IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERY
spellingShingle IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERY
Valentim, Maria
title_short IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERY
title_full IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERY
title_fullStr IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERY
title_full_unstemmed IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERY
title_sort IMPACT OF VISCERAL OBESITY ON OUTCOMES OF PERIAMPULLARY CANCER SURGERY
author Valentim, Maria
author_facet Valentim, Maria
Silva, Patrícia
Pereira, Ana
Vilaça, Sónia
Costa, Catarina
Martins, Sandra F.
author_role author
author2 Silva, Patrícia
Pereira, Ana
Vilaça, Sónia
Costa, Catarina
Martins, Sandra F.
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Valentim, Maria
Silva, Patrícia
Pereira, Ana
Vilaça, Sónia
Costa, Catarina
Martins, Sandra F.
description Periampullary cancers are located up to a maximum distance of 2 cm from the duodenal papilla, with pancreatic cancer being the most common. Despite advances in surgical technique, survival rates remain low, making it essential to identify prognostic factors. Visceral obesity has been identified as a risk factor for cancer development, but its influence on the morbidity and mortality of operated patients remains controversial. This study aims to identify an association between the presence of preoperative visceral obesity and an increased risk of postoperative morbimortality in patients with periampullary cancers at Hospital de Braga. The sample includes 44 patients with periampullary cancers who underwent surgery with a curative intention between January/2011 and April/2018. The area of visceral fat was measured using the ImageJ software. Statistical analysis was performed using the SPSS software version 25. Visceral fat was not implicated in longer hospital stay or postoperative complications. The survival analysis showed no differences in disease-free survival at 1 year (p = 0.121) and 5 years (p = 0.222) or in overall survival at 1 year (p = 0.163) and 5 years (p = 0.053) between groups. Our data suggest that preoperative visceral obesity is not a risk factor for greater postoperative morbidity and mortality in individuals with periampullary cancers. Despite the reduced sample, this study evaluates visceral obesity in four types of tumors with many similar characteristics. Additional studies with larger samples are needed to confirm our observations.
publishDate 2022
dc.date.none.fl_str_mv 2022-02-02
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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dc.identifier.uri.fl_str_mv https://doi.org/10.34635/rpc.942
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url https://doi.org/10.34635/rpc.942
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://revista.spcir.com/index.php/spcir/article/view/942
https://revista.spcir.com/index.php/spcir/article/view/942/618
dc.rights.driver.fl_str_mv Copyright (c) 2021 Revista Portuguesa de Cirurgia
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rights_invalid_str_mv Copyright (c) 2021 Revista Portuguesa de Cirurgia
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dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Cirurgia
publisher.none.fl_str_mv Sociedade Portuguesa de Cirurgia
dc.source.none.fl_str_mv Revista Portuguesa de Cirurgia; No 51 (2021): Number 51 - October 2021; 45-52
Revista Portuguesa de Cirurgia; No 51 (2021): Number 51 - October 2021; 45-52
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