Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report

Detalhes bibliográficos
Autor(a) principal: Di Giovanni, Silvia Eleonora
Data de Publicação: 2016
Outros Autores: Cunha, Teresa Margarida, Duarte, Ana Luisa, Alves, Ines
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706
Resumo: Female genital tuberculosis remains a major health problem in developing countries and is an important cause of infertility. As symptoms, laboratory data and physical findings are non-specific, its diagnosis can be difficult. We describe a case of a 39-year-old woman suffering from peri-umbilical pain and increased abdominal size for one year, anorexia, asthenia, weight loss, occasionally dysuria and dyspareunia, and four months amenorrhea. Laboratory data revealed cancer antigen 125 (CA-125) level of 132.3 U/mL, erythrocyte sedimentation rate of 42 mm/h, and gamma-globulins of 2.66 g/dL. Computed tomography scan showed loculated ascites. It was initially suspected a carcinomatous origin, but ascites evaluation was negative for malignant cells. Magnetic resonance imaging from another hospital showed endometrial heterogeneity. Therefore, an endometrial biopsy was performed demonstrating an inflammatory infiltrate with giant cells of type Langhans and bacteriological culture identified Mycobacterium tuberculosis.
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spelling Endometrial Tuberculosis Simulating an Ovarian Cancer: a case reportTuberculose Endometrial Simulando um Carcinoma do OvárioTuberculosisFemale GenitalEndometritisPeritonitisTuberculousOvarian Neoplasms.Tuberculose Genital FemininaEndometritePeritonite TuberculosaNeoplassia do Ovário.Female genital tuberculosis remains a major health problem in developing countries and is an important cause of infertility. As symptoms, laboratory data and physical findings are non-specific, its diagnosis can be difficult. We describe a case of a 39-year-old woman suffering from peri-umbilical pain and increased abdominal size for one year, anorexia, asthenia, weight loss, occasionally dysuria and dyspareunia, and four months amenorrhea. Laboratory data revealed cancer antigen 125 (CA-125) level of 132.3 U/mL, erythrocyte sedimentation rate of 42 mm/h, and gamma-globulins of 2.66 g/dL. Computed tomography scan showed loculated ascites. It was initially suspected a carcinomatous origin, but ascites evaluation was negative for malignant cells. Magnetic resonance imaging from another hospital showed endometrial heterogeneity. Therefore, an endometrial biopsy was performed demonstrating an inflammatory infiltrate with giant cells of type Langhans and bacteriological culture identified Mycobacterium tuberculosis.A tuberculose genital feminina continua a representar uma patologia importante nos países em desenvolvimento e constitui uma causa importante de infertilidade. Os seus sintomas, achados laboratoriais e exame físico não são específicos, tornando difícil o seu dia-gnóstico. Descrevemos o caso de uma doente do sexo feminino, de 39 anos, com dor peri-umbilical e aumento do volume abdominal desde há um ano, anorexia, astenia, perda ponderal, ocasionalmente disúria e dispareunia, assim como amenorreia desde há quatro meses. Os dados laboratoriais mostraram valores de 132,3 U/mL do marcador tumoral CA-125, 42 mm/h de velocidade de sedimentação e 2,66 g/dL de gama-globulinas. A tomografia computadorizada mostrou ascite loculada. Inicialmente suspeitou-se de etiologia maligna, mas o exame citológico do líquido ascítico foi negativo para células malignas. Foi efectuada ressonância magnética pélvica, noutra instituição, que revelou heterogeneidade do endométrio. Foi então realizada biópsia endometrial que revelou um infiltrado inflamatório com células gigantes de Langhans e o exame bacteriológico isolou Mycobacterium tuberculosis.Ordem dos Médicos2016-06-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfimage/tiffimage/tiffimage/tiffapplication/pdfapplication/pdfimage/tiffimage/tiffapplication/mswordapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706oai:ojs.www.actamedicaportuguesa.com:article/7706Acta Médica Portuguesa; Vol. 29 No. 6 (2016): June; 412-415Acta Médica Portuguesa; Vol. 29 N.º 6 (2016): Junho; 412-4151646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/4720https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/8413https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/8414https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/8415https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/8416https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/8417https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/8491https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/8492https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/8494https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/7706/8530Direitos de Autor (c) 2016 Acta Médica Portuguesa - Ordem dos Médicosinfo:eu-repo/semantics/openAccessDi Giovanni, Silvia EleonoraCunha, Teresa MargaridaDuarte, Ana LuisaAlves, Ines2022-12-20T11:05:18Zoai:ojs.www.actamedicaportuguesa.com:article/7706Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:29.362925Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report
Tuberculose Endometrial Simulando um Carcinoma do Ovário
title Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report
spellingShingle Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report
Di Giovanni, Silvia Eleonora
Tuberculosis
Female Genital
Endometritis
Peritonitis
Tuberculous
Ovarian Neoplasms.
Tuberculose Genital Feminina
Endometrite
Peritonite Tuberculosa
Neoplassia do Ovário.
title_short Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report
title_full Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report
title_fullStr Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report
title_full_unstemmed Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report
title_sort Endometrial Tuberculosis Simulating an Ovarian Cancer: a case report
author Di Giovanni, Silvia Eleonora
author_facet Di Giovanni, Silvia Eleonora
Cunha, Teresa Margarida
Duarte, Ana Luisa
Alves, Ines
author_role author
author2 Cunha, Teresa Margarida
Duarte, Ana Luisa
Alves, Ines
author2_role author
author
author
dc.contributor.author.fl_str_mv Di Giovanni, Silvia Eleonora
Cunha, Teresa Margarida
Duarte, Ana Luisa
Alves, Ines
dc.subject.por.fl_str_mv Tuberculosis
Female Genital
Endometritis
Peritonitis
Tuberculous
Ovarian Neoplasms.
Tuberculose Genital Feminina
Endometrite
Peritonite Tuberculosa
Neoplassia do Ovário.
topic Tuberculosis
Female Genital
Endometritis
Peritonitis
Tuberculous
Ovarian Neoplasms.
Tuberculose Genital Feminina
Endometrite
Peritonite Tuberculosa
Neoplassia do Ovário.
description Female genital tuberculosis remains a major health problem in developing countries and is an important cause of infertility. As symptoms, laboratory data and physical findings are non-specific, its diagnosis can be difficult. We describe a case of a 39-year-old woman suffering from peri-umbilical pain and increased abdominal size for one year, anorexia, asthenia, weight loss, occasionally dysuria and dyspareunia, and four months amenorrhea. Laboratory data revealed cancer antigen 125 (CA-125) level of 132.3 U/mL, erythrocyte sedimentation rate of 42 mm/h, and gamma-globulins of 2.66 g/dL. Computed tomography scan showed loculated ascites. It was initially suspected a carcinomatous origin, but ascites evaluation was negative for malignant cells. Magnetic resonance imaging from another hospital showed endometrial heterogeneity. Therefore, an endometrial biopsy was performed demonstrating an inflammatory infiltrate with giant cells of type Langhans and bacteriological culture identified Mycobacterium tuberculosis.
publishDate 2016
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dc.rights.driver.fl_str_mv Direitos de Autor (c) 2016 Acta Médica Portuguesa - Ordem dos Médicos
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 29 No. 6 (2016): June; 412-415
Acta Médica Portuguesa; Vol. 29 N.º 6 (2016): Junho; 412-415
1646-0758
0870-399X
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