Lower airway flow influences peak nasal inspiratory flow in school-aged children*

Detalhes bibliográficos
Autor(a) principal: Pité, Helena
Data de Publicação: 2018
Outros Autores: Pimenta, Lara, Henriques, Ana Cristina, Marques, Inês, Camarinha, Catarina, Lourenço, Ana Verónica, Almeida, Isabel, Borrego, Luís Miguel, Morais-Almeida, Mário
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/151575
Resumo: Funding: This work has been partially supported by a grant from AstraZeneca®. Thermo Fisher Scientific, Inc. provided the materials for exhaled nitric oxide measurements. AstraZeneca® and Thermo Fisher Scientific, Inc. had no role in the study design, conduct of the research, preparation or submission of the article
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spelling Lower airway flow influences peak nasal inspiratory flow in school-aged children*AsthmaChildrenPeak expiratory flow (pef)Peak nasal inspiratory flow (pnif)RhinitisOtorhinolaryngologyFunding: This work has been partially supported by a grant from AstraZeneca®. Thermo Fisher Scientific, Inc. provided the materials for exhaled nitric oxide measurements. AstraZeneca® and Thermo Fisher Scientific, Inc. had no role in the study design, conduct of the research, preparation or submission of the articleBackground: Rhinitis and asthma frequently coexist. Peak nasal inspiratory flow (PNIF) objectively evaluates nasal obstruction. Lower airway flow’s impact on PNIF has seldom been analysed in children. We aimed to study the associations between PNIF and: (1)forced expiratory volume in one second (FEV1) and peak expiratory flow (PEF) in children with allergic rhinitis and asthma and healthy controls; (2)allergic rhinitis and asthma control subjective evaluation. Methods: Sequential assessments of PNIF before and after nasal decongestion and spirometry with bronchodilation test were performed in 65 children (6-12 years) with allergic rhinitis and asthma, and 24 gender, age-matched healthy controls. The Control of Allergic Rhinitis and Asthma Test in children (CARATkids) was used for control assessment. Associations were investigated by multiple linear regression models. Results: Baseline and decongested PNIF correlated with baseline and post-bronchodilation FEV1 and PEF, observed independently of rhinitis and asthma diagnosis. The best model for PNIF included PEF, age and gender. No association was found between PNIF and CARATkids scores, except for nasal obstruction self-report. Conclusion: In school-aged children, besides age and gender, PEF values should ideally be known to interpret PNIF values. PNIF can be complementary to subjective control assessment in children with allergic rhinitis and asthma.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Centro de Estudos de Doenças Crónicas (CEDOC)RUNPité, HelenaPimenta, LaraHenriques, Ana CristinaMarques, InêsCamarinha, CatarinaLourenço, Ana VerónicaAlmeida, IsabelBorrego, Luís MiguelMorais-Almeida, Mário2023-04-04T22:12:25Z20182018-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article9application/pdfhttp://hdl.handle.net/10362/151575eng0300-0729PURE: 6097758https://doi.org/10.4193/Rhin17.229info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:34:01Zoai:run.unl.pt:10362/151575Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:54:38.700740Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Lower airway flow influences peak nasal inspiratory flow in school-aged children*
title Lower airway flow influences peak nasal inspiratory flow in school-aged children*
spellingShingle Lower airway flow influences peak nasal inspiratory flow in school-aged children*
Pité, Helena
Asthma
Children
Peak expiratory flow (pef)
Peak nasal inspiratory flow (pnif)
Rhinitis
Otorhinolaryngology
title_short Lower airway flow influences peak nasal inspiratory flow in school-aged children*
title_full Lower airway flow influences peak nasal inspiratory flow in school-aged children*
title_fullStr Lower airway flow influences peak nasal inspiratory flow in school-aged children*
title_full_unstemmed Lower airway flow influences peak nasal inspiratory flow in school-aged children*
title_sort Lower airway flow influences peak nasal inspiratory flow in school-aged children*
author Pité, Helena
author_facet Pité, Helena
Pimenta, Lara
Henriques, Ana Cristina
Marques, Inês
Camarinha, Catarina
Lourenço, Ana Verónica
Almeida, Isabel
Borrego, Luís Miguel
Morais-Almeida, Mário
author_role author
author2 Pimenta, Lara
Henriques, Ana Cristina
Marques, Inês
Camarinha, Catarina
Lourenço, Ana Verónica
Almeida, Isabel
Borrego, Luís Miguel
Morais-Almeida, Mário
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Centro de Estudos de Doenças Crónicas (CEDOC)
RUN
dc.contributor.author.fl_str_mv Pité, Helena
Pimenta, Lara
Henriques, Ana Cristina
Marques, Inês
Camarinha, Catarina
Lourenço, Ana Verónica
Almeida, Isabel
Borrego, Luís Miguel
Morais-Almeida, Mário
dc.subject.por.fl_str_mv Asthma
Children
Peak expiratory flow (pef)
Peak nasal inspiratory flow (pnif)
Rhinitis
Otorhinolaryngology
topic Asthma
Children
Peak expiratory flow (pef)
Peak nasal inspiratory flow (pnif)
Rhinitis
Otorhinolaryngology
description Funding: This work has been partially supported by a grant from AstraZeneca®. Thermo Fisher Scientific, Inc. provided the materials for exhaled nitric oxide measurements. AstraZeneca® and Thermo Fisher Scientific, Inc. had no role in the study design, conduct of the research, preparation or submission of the article
publishDate 2018
dc.date.none.fl_str_mv 2018
2018-01-01T00:00:00Z
2023-04-04T22:12:25Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/151575
url http://hdl.handle.net/10362/151575
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0300-0729
PURE: 6097758
https://doi.org/10.4193/Rhin17.229
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 9
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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