A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhibitors
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17313 |
Resumo: | Angiotensin converting enzyme inhibitors (ACEi) are widely used for the treatment of multiple conditions such as hypertension, heart failure and chronic kidney disease. Angioedema is a rare but potentially fatal complication of ACEi use and unilateral tongue edema is a very rare presentation. We report a case of a 55-year-old man, with a history of hypertension, on enalapril for three years, who presented to the hospital with unilateral tongue swelling, without airway compromise. Other causes were excluded and the diagnosis of angioedema due to enalapril was established. The patient was discharged with discontinuation of ACEi with total resolution of symptoms and without relapse after several months. Although very rare, unilateral tongue swelling should be considered in the presentation of angioedema associated with ACEi. Tight surveillance is important to prevent fatal complications such as airway obstruction. ACEi discontinuation is crucial to avoid clinical relapse. |
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A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme InhibitorsUm Caso Raro de Edema Unilateral da Língua com Inibidores da Enzima de Conversão da AngiotensinaAngioedemaAngiotensin-Converting Enzyme InhibitorsEnalaprilAngioedemaEnalaprilInibidores da Enzima de Conversão da AngiotensinaAngiotensin converting enzyme inhibitors (ACEi) are widely used for the treatment of multiple conditions such as hypertension, heart failure and chronic kidney disease. Angioedema is a rare but potentially fatal complication of ACEi use and unilateral tongue edema is a very rare presentation. We report a case of a 55-year-old man, with a history of hypertension, on enalapril for three years, who presented to the hospital with unilateral tongue swelling, without airway compromise. Other causes were excluded and the diagnosis of angioedema due to enalapril was established. The patient was discharged with discontinuation of ACEi with total resolution of symptoms and without relapse after several months. Although very rare, unilateral tongue swelling should be considered in the presentation of angioedema associated with ACEi. Tight surveillance is important to prevent fatal complications such as airway obstruction. ACEi discontinuation is crucial to avoid clinical relapse.Os inibidores da enzima de conversão da angiotensina (iECAs) são amplamente usados no tratamento de várias patologias como a hipertensão arterial, insuficiência cardíaca e doença renal crónica. O angioedema é uma complicação rara mas potencialmente fatal desta medicação e o edema unilateral da língua é uma apresentação rara desta condição. Reportamos o caso de um homem de 55 anos com hipertensão, medicado há três anos com enalapril, que à admissão hospitalar apresentava edema unilateral da língua sem compromisso da via aérea. Outras etiologias foram excluídas, tendo-se assumido o diagnóstico de angioedema associado ao enalapril. Após suspensão do iECA os sintomas diminuíram progressivamente, sem recorrência do quadro após vários meses. Ainda que raro, o edema unilateral da língua deve ser considerado na apresentação do angioedema associado a iECA. É importante uma vigilância apertada para prevenir complicações fatais, tais como a obstrução da via aérea. A descontinuação do iECA é fundamental para evitar recidiva.Ordem dos Médicos2022-07-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17313oai:ojs.www.actamedicaportuguesa.com:article/17313Acta Médica Portuguesa; Vol. 35 No. 7-8 (2022): July-August; 588-590Acta Médica Portuguesa; Vol. 35 N.º 7-8 (2022): Julho-Agosto; 588-5901646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17313https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17313/6642Direitos de Autor (c) 2022 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessGil Braga, BeatrizCravo, MárciaNeves, PedroPinto, FilipeMendonça, Catarina2022-12-20T11:08:01Zoai:ojs.www.actamedicaportuguesa.com:article/17313Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:20:55.640054Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhibitors Um Caso Raro de Edema Unilateral da Língua com Inibidores da Enzima de Conversão da Angiotensina |
title |
A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhibitors |
spellingShingle |
A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhibitors Gil Braga, Beatriz Angioedema Angiotensin-Converting Enzyme Inhibitors Enalapril Angioedema Enalapril Inibidores da Enzima de Conversão da Angiotensina |
title_short |
A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhibitors |
title_full |
A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhibitors |
title_fullStr |
A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhibitors |
title_full_unstemmed |
A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhibitors |
title_sort |
A Rare Case of Unilateral Tongue Edema with Angiotensin Converting Enzyme Inhibitors |
author |
Gil Braga, Beatriz |
author_facet |
Gil Braga, Beatriz Cravo, Márcia Neves, Pedro Pinto, Filipe Mendonça, Catarina |
author_role |
author |
author2 |
Cravo, Márcia Neves, Pedro Pinto, Filipe Mendonça, Catarina |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Gil Braga, Beatriz Cravo, Márcia Neves, Pedro Pinto, Filipe Mendonça, Catarina |
dc.subject.por.fl_str_mv |
Angioedema Angiotensin-Converting Enzyme Inhibitors Enalapril Angioedema Enalapril Inibidores da Enzima de Conversão da Angiotensina |
topic |
Angioedema Angiotensin-Converting Enzyme Inhibitors Enalapril Angioedema Enalapril Inibidores da Enzima de Conversão da Angiotensina |
description |
Angiotensin converting enzyme inhibitors (ACEi) are widely used for the treatment of multiple conditions such as hypertension, heart failure and chronic kidney disease. Angioedema is a rare but potentially fatal complication of ACEi use and unilateral tongue edema is a very rare presentation. We report a case of a 55-year-old man, with a history of hypertension, on enalapril for three years, who presented to the hospital with unilateral tongue swelling, without airway compromise. Other causes were excluded and the diagnosis of angioedema due to enalapril was established. The patient was discharged with discontinuation of ACEi with total resolution of symptoms and without relapse after several months. Although very rare, unilateral tongue swelling should be considered in the presentation of angioedema associated with ACEi. Tight surveillance is important to prevent fatal complications such as airway obstruction. ACEi discontinuation is crucial to avoid clinical relapse. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-07-01 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17313 oai:ojs.www.actamedicaportuguesa.com:article/17313 |
url |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17313 |
identifier_str_mv |
oai:ojs.www.actamedicaportuguesa.com:article/17313 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17313 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/17313/6642 |
dc.rights.driver.fl_str_mv |
Direitos de Autor (c) 2022 Acta Médica Portuguesa info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
Direitos de Autor (c) 2022 Acta Médica Portuguesa |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 35 No. 7-8 (2022): July-August; 588-590 Acta Médica Portuguesa; Vol. 35 N.º 7-8 (2022): Julho-Agosto; 588-590 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1817553812335886336 |