Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/101060 https://doi.org/10.47276/lr.92.4.398 |
Resumo: | Introduction This is a case-control study aiming to analyze the predictive factors for the occurrence of leprosy in contacts under 15 years of age, considering aspects related to the socio-environmental and epidemiological conditions in a hyperendemic municipality. Methods Cases (n = 30) consisted of children with leprosy who were household contacts of adults notified with leprosy between 2016 and 2018. The controls (n = 128) comprised neighborhood contacts, without symptoms of leprosy, living within a radius of less than 100 m of the households with cases. Demographic, social, environmental, and epidemiological variables were analyzed. The software SPSS, version 20, was used. Odds Ratio and statistical significance level of p ≤ 0.05 were considered for association analysis. In the logistic regression analysis, the variables with results ≤20% were selected. Results After adjustments, the predictive variables for the occurrence of leprosy were age between 8 and 14 years (OR adjust = 4.5; 95% CI: 1.70; 12.18) and a family history of leprosy (OR adjust = 5.2; 95% CI: 1.95; 14.13). Conclusions The predictive factors studied may favor the occurrence of leprosy in those most vulnerable to this disease in the child population; strategies such as the use of immune chemoprophylaxis are recommended, especially in hyperendemic regions, such as the state of Mato Grosso. |
id |
RCAP_751098734539a09434d3a7b23bb897a2 |
---|---|
oai_identifier_str |
oai:estudogeral.uc.pt:10316/101060 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of BrazilLeprosyrisk factorcontactchild populationIntroduction This is a case-control study aiming to analyze the predictive factors for the occurrence of leprosy in contacts under 15 years of age, considering aspects related to the socio-environmental and epidemiological conditions in a hyperendemic municipality. Methods Cases (n = 30) consisted of children with leprosy who were household contacts of adults notified with leprosy between 2016 and 2018. The controls (n = 128) comprised neighborhood contacts, without symptoms of leprosy, living within a radius of less than 100 m of the households with cases. Demographic, social, environmental, and epidemiological variables were analyzed. The software SPSS, version 20, was used. Odds Ratio and statistical significance level of p ≤ 0.05 were considered for association analysis. In the logistic regression analysis, the variables with results ≤20% were selected. Results After adjustments, the predictive variables for the occurrence of leprosy were age between 8 and 14 years (OR adjust = 4.5; 95% CI: 1.70; 12.18) and a family history of leprosy (OR adjust = 5.2; 95% CI: 1.95; 14.13). Conclusions The predictive factors studied may favor the occurrence of leprosy in those most vulnerable to this disease in the child population; strategies such as the use of immune chemoprophylaxis are recommended, especially in hyperendemic regions, such as the state of Mato Grosso.2021info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/101060http://hdl.handle.net/10316/101060https://doi.org/10.47276/lr.92.4.398eng2162-8807da Silva, Fabiane VerônicaSousa, Gutembergue dos SantosSilva, Pãmela Rodrigues de Souzados Santos, Emerson SoaresMachado, R. B. F.Cortela, Denise da Costa BoamorteFerreira, Silvana Margarida Benevidesinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-07-30T02:42:05Zoai:estudogeral.uc.pt:10316/101060Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:18:20.543879Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil |
title |
Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil |
spellingShingle |
Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil da Silva, Fabiane Verônica Leprosy risk factor contact child population |
title_short |
Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil |
title_full |
Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil |
title_fullStr |
Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil |
title_full_unstemmed |
Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil |
title_sort |
Social, environmental, and epidemiological aspects of leprosy occurrence in children in a hyperendemic region of Brazil |
author |
da Silva, Fabiane Verônica |
author_facet |
da Silva, Fabiane Verônica Sousa, Gutembergue dos Santos Silva, Pãmela Rodrigues de Souza dos Santos, Emerson Soares Machado, R. B. F. Cortela, Denise da Costa Boamorte Ferreira, Silvana Margarida Benevides |
author_role |
author |
author2 |
Sousa, Gutembergue dos Santos Silva, Pãmela Rodrigues de Souza dos Santos, Emerson Soares Machado, R. B. F. Cortela, Denise da Costa Boamorte Ferreira, Silvana Margarida Benevides |
author2_role |
author author author author author author |
dc.contributor.author.fl_str_mv |
da Silva, Fabiane Verônica Sousa, Gutembergue dos Santos Silva, Pãmela Rodrigues de Souza dos Santos, Emerson Soares Machado, R. B. F. Cortela, Denise da Costa Boamorte Ferreira, Silvana Margarida Benevides |
dc.subject.por.fl_str_mv |
Leprosy risk factor contact child population |
topic |
Leprosy risk factor contact child population |
description |
Introduction This is a case-control study aiming to analyze the predictive factors for the occurrence of leprosy in contacts under 15 years of age, considering aspects related to the socio-environmental and epidemiological conditions in a hyperendemic municipality. Methods Cases (n = 30) consisted of children with leprosy who were household contacts of adults notified with leprosy between 2016 and 2018. The controls (n = 128) comprised neighborhood contacts, without symptoms of leprosy, living within a radius of less than 100 m of the households with cases. Demographic, social, environmental, and epidemiological variables were analyzed. The software SPSS, version 20, was used. Odds Ratio and statistical significance level of p ≤ 0.05 were considered for association analysis. In the logistic regression analysis, the variables with results ≤20% were selected. Results After adjustments, the predictive variables for the occurrence of leprosy were age between 8 and 14 years (OR adjust = 4.5; 95% CI: 1.70; 12.18) and a family history of leprosy (OR adjust = 5.2; 95% CI: 1.95; 14.13). Conclusions The predictive factors studied may favor the occurrence of leprosy in those most vulnerable to this disease in the child population; strategies such as the use of immune chemoprophylaxis are recommended, especially in hyperendemic regions, such as the state of Mato Grosso. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/101060 http://hdl.handle.net/10316/101060 https://doi.org/10.47276/lr.92.4.398 |
url |
http://hdl.handle.net/10316/101060 https://doi.org/10.47276/lr.92.4.398 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2162-8807 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799134078319984640 |