Left supraclavicular lymph node enlargement as the initial manifestation of metastatic prostate cancer

• Autor(a) principal: Dutschmann, Rita
• Data de Publicação: 2008
• Outros Autores: Nunes da Silva, Maria João, Pires, Carlos, Costa, Luís, Lucas, Margarida, M. M. Vitorino, Rui
• Tipo de documento: Artigo
• Idioma: por
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: https://revista.spmi.pt/index.php/rpmi/article/view/1463
• topic: Carcinoma da próstata; metástases; adenopatias supraclaviculares; Prostate cancer; metastasis; supraclavicular nodes

The involvement of supraclavicular lymph nodes in metastatic prostate cancer is usually considered uncommon, and is extremely rare as the initial manifestation of the disease. We describe the clinical case of a 77 year-old man, who presented with left supraclavicular lymphadenopathy for 3 months, with no other symptoms. The investigation led to the diagnosis of prostate cancer with metastatic ganglionar dissemination. Hormonal therapy induced an almost complete regression of all lymphadenopathies and a reduction of PSA from 4642 ng/dl to 0.1 ng/dl. Prostate cancer must always be considered in the differential diagnosis of supraclavicular lymphadenopathies in patients with more than 45 year-old, even in the absence of prostatic symptoms. The recent suggestion that this presentation could be more frequent than traditionally reported is discussed.