Male gender is an important clinical risk factor for iron deficiency in healthy infants

Detalhes bibliográficos
Autor(a) principal: Antunes, Henedina
Data de Publicação: 2012
Outros Autores: Santos, Cristina, Carvalho, Susana, Gonçalves, Sónia, Pereira, Altamiro Costa
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/24204
Resumo: Author's personal copy ; Acknowledgements to the children and families who were involved in this study, and to BH Pathology Clinic Dpt.
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spelling Male gender is an important clinical risk factor for iron deficiency in healthy infantsIron deficiencyGenderInfantsRisk profileIron deficiency anaemiaAuthor's personal copy ; Acknowledgements to the children and families who were involved in this study, and to BH Pathology Clinic Dpt.Background & aims: To identify ID risk factors in infancy, and try to explore why ID is more prevalent in boys than in girls in the first year of life. Methods: A multiple logistic regression was performed on data of 201 infants, with ferritin<12 ng/ml as the dependent variable and months of breastfeeding, weight gain from birth to 9 months (WG), and gender as independent variables. To compare haematological parameters we used Manne-Whitney and t test. Results: From the 39 infants with IDA (19.4%), 24 (61.5%) were male and of the 162 infants without IDA, 50% were male (p ¼ 0.195). The median(minimum; maximum) ferritin concentrations in male infants at 9 months was of 9.8 ng/ml (0.5e67.0 ng/ml) and in females 14 ng/ml (0.5e74.5 ng/ml), p < 0.001. The average (±SD) WG was of 5863.3 g (±855.4 g) in male infants and 5556.9 g (±1054.3 g) in female infants (p = 0.027). A multiple logistic regression (OR; 95%CI) showed that male gender was the most important risk factor (OR: 3.3; 1.7e6.3; p < 0.001), followed by a higher weight increase (OR: 1.6; CI [1.1; 2.2]; p = 0.016) and longer breastfeeding time (OR: 1.1; CI [0.98; 1.2]; p = 0.099). Comparison of other haematological parameters at 9 months in relation to gender (males (M): 105; females (F): 96) showed significant differences in: mean ± SD, Mean Corpuscular Haemoglobin (M: 25.0 ± 2.1; F: 25.8 ± 2.4 pg, p = 0.001), Mean Corpuscular Volume (M: 73.4 ± 4.1; F: 75.3 ± 4.2 fl, 0.009), RDW (M: 14.6 ± 1.5; F: 14.1 ± 1.6%, p = 0.048), Plaquelets (M: 324.9 ± 77.9; F: 350.5 ± 81.4 x 10³/µl, p = 0.026). Conclusions: ID was significantly more frequent in male infants, independent of rapid growth or longer breastfeeding duration. The clinical risk profile for ID in infants includes male gender and not only rapid growth, and longer breastfeeding duration.This study received a scholarship from the Foment Commission for Investigation in Health Care, from the Health Ministry P.I. nº 87/07.ElsevierUniversidade do MinhoAntunes, HenedinaSantos, CristinaCarvalho, SusanaGonçalves, SóniaPereira, Altamiro Costa2012-122012-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/24204eng2212-826310.1016/j.clnme.2012.09.001info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:19:15Zoai:repositorium.sdum.uminho.pt:1822/24204Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:12:09.719804Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Male gender is an important clinical risk factor for iron deficiency in healthy infants
title Male gender is an important clinical risk factor for iron deficiency in healthy infants
spellingShingle Male gender is an important clinical risk factor for iron deficiency in healthy infants
Antunes, Henedina
Iron deficiency
Gender
Infants
Risk profile
Iron deficiency anaemia
title_short Male gender is an important clinical risk factor for iron deficiency in healthy infants
title_full Male gender is an important clinical risk factor for iron deficiency in healthy infants
title_fullStr Male gender is an important clinical risk factor for iron deficiency in healthy infants
title_full_unstemmed Male gender is an important clinical risk factor for iron deficiency in healthy infants
title_sort Male gender is an important clinical risk factor for iron deficiency in healthy infants
author Antunes, Henedina
author_facet Antunes, Henedina
Santos, Cristina
Carvalho, Susana
Gonçalves, Sónia
Pereira, Altamiro Costa
author_role author
author2 Santos, Cristina
Carvalho, Susana
Gonçalves, Sónia
Pereira, Altamiro Costa
author2_role author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Antunes, Henedina
Santos, Cristina
Carvalho, Susana
Gonçalves, Sónia
Pereira, Altamiro Costa
dc.subject.por.fl_str_mv Iron deficiency
Gender
Infants
Risk profile
Iron deficiency anaemia
topic Iron deficiency
Gender
Infants
Risk profile
Iron deficiency anaemia
description Author's personal copy ; Acknowledgements to the children and families who were involved in this study, and to BH Pathology Clinic Dpt.
publishDate 2012
dc.date.none.fl_str_mv 2012-12
2012-12-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/24204
url http://hdl.handle.net/1822/24204
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2212-8263
10.1016/j.clnme.2012.09.001
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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