Recurrent parotitis in children- case series and literature review

Detalhes bibliográficos
Autor(a) principal: Mendes, Ana Raquel
Data de Publicação: 2021
Outros Autores: Moreira, Liane, Dias, Ângela, Lopes, Andreia, Lobo, Ana Luísa, Simão, Teresa São
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://revistas.rcaap.pt/nascercrescer/article/view/20543
Resumo: Introduction: Recurrent parotitis is defined as the occurrence of two or more episodes of the parotid gland. Several etiologies should be addressed in the approach to these patients. The aim of this study was to investigate the clinical, laboratory, and imaging profile of children with recurrent parotitis. Material and Methods: Retrospective review of the medical records of patients referred to a Pediatric Outpatient Clinic between January 2013 and June 2018.  Results: The medical records of 24 patients with recurrent parotitis (66.7% male) and a mean age of seven years and five months were reviewed. The median age of onset of episodes was five years and three months. Unilateral and non-febrile episodes prevailed. Non-steroidal anti-inflammatory drugs were universally used to treat symptoms. Non-acute parotid and neck ultrasound predominantly showed the presence of a heterogeneous gland (57.1%). Sialography performed in five patients suggested chronic parotitis in two and Sjögren syndrome/ sarcoidosis in one. No significant immunologic defects were found beside a mild C3 reduction in one patient and C4 reduction in another patient, apparently without clinical relevance. A single patient tested positive for antinuclear antibodies. Immunoglobulin A deficit was found in one case. The most common final diagnosis was juvenile recurrent parotitis (37.5%). Conclusions: Most cases of recurrent parotitis in pediatric age have benign etiology. A more judicious request of complementary exams in the acute and non-acute phases could be time- and cost-effective.
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spelling Recurrent parotitis in children- case series and literature reviewParotidite recorrente em crianças − casuística e revisão da literaturaOriginal ArticlesIntroduction: Recurrent parotitis is defined as the occurrence of two or more episodes of the parotid gland. Several etiologies should be addressed in the approach to these patients. The aim of this study was to investigate the clinical, laboratory, and imaging profile of children with recurrent parotitis. Material and Methods: Retrospective review of the medical records of patients referred to a Pediatric Outpatient Clinic between January 2013 and June 2018.  Results: The medical records of 24 patients with recurrent parotitis (66.7% male) and a mean age of seven years and five months were reviewed. The median age of onset of episodes was five years and three months. Unilateral and non-febrile episodes prevailed. Non-steroidal anti-inflammatory drugs were universally used to treat symptoms. Non-acute parotid and neck ultrasound predominantly showed the presence of a heterogeneous gland (57.1%). Sialography performed in five patients suggested chronic parotitis in two and Sjögren syndrome/ sarcoidosis in one. No significant immunologic defects were found beside a mild C3 reduction in one patient and C4 reduction in another patient, apparently without clinical relevance. A single patient tested positive for antinuclear antibodies. Immunoglobulin A deficit was found in one case. The most common final diagnosis was juvenile recurrent parotitis (37.5%). Conclusions: Most cases of recurrent parotitis in pediatric age have benign etiology. A more judicious request of complementary exams in the acute and non-acute phases could be time- and cost-effective.Introdução: A parotidite recorrente é definida como a ocorrência de dois ou mais episódios de inflamação da glândula parótida. Várias etiologias devem ser consideradas na abordagem a estes doentes. O objetivo deste estudo foi investigar o perfil clínico, laboratorial e imagiológico de crianças com parotidite recorrente. Material e Métodos: Análise retrospetiva dos processos clínicos de doentes referenciados a uma consulta de Pediatria entre janeiro de 2013 e junho de 2018. Resultados: Foram revistos os processos clínicos de 24 doentes com parotidite recorrente (66,7% do sexo masculino), com uma idade média de sete anos e cinco meses. A idade mediana de início dos episódios foi de cinco anos e três meses e predominaram os episódios unilaterais e não-febris. Foram universalmente utilizados anti-inflamatórios não-esteroides no tratamento sintomático. A heterogeneidade da glândula foi o padrão predominante na ecografia parotídea da fase não-aguda (57,1%). Foi realizada sialografia em cinco doentes, tendo sido sugestiva de parotidite crónica em dois e de síndrome de Sjögren syndrome/sarcoidose em um. Não foram identificados defeitos imunológicos significativos, exceto uma discreta diminuição do valor de C3 em um doente e de C4 em outro, sem relevância clínica. Foram identificados anticorpos antinucleares positivos num doente e défice de imunoglobulina A noutro. O diagnóstico final mais prevalente foi parotidite recorrente idiopática. Conclusão: A maioria dos casos de parotidite recorrente em idade pediátrica é de etiologia benigna. Uma requisição mais criteriosa de exames complementares na fase aguda e não-aguda pode ser mais eficaz a nível de tempo e custos.Centro Hospitalar Universitário do Porto2021-12-27T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://revistas.rcaap.pt/nascercrescer/article/view/20543eng2183-9417Mendes, Ana RaquelMoreira, LianeDias, ÂngelaLopes, AndreiaLobo, Ana LuísaSimão, Teresa Sãoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-09-21T14:55:40Zoai:ojs.revistas.rcaap.pt:article/20543Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T15:56:32.435755Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Recurrent parotitis in children- case series and literature review
Parotidite recorrente em crianças − casuística e revisão da literatura
title Recurrent parotitis in children- case series and literature review
spellingShingle Recurrent parotitis in children- case series and literature review
Mendes, Ana Raquel
Original Articles
title_short Recurrent parotitis in children- case series and literature review
title_full Recurrent parotitis in children- case series and literature review
title_fullStr Recurrent parotitis in children- case series and literature review
title_full_unstemmed Recurrent parotitis in children- case series and literature review
title_sort Recurrent parotitis in children- case series and literature review
author Mendes, Ana Raquel
author_facet Mendes, Ana Raquel
Moreira, Liane
Dias, Ângela
Lopes, Andreia
Lobo, Ana Luísa
Simão, Teresa São
author_role author
author2 Moreira, Liane
Dias, Ângela
Lopes, Andreia
Lobo, Ana Luísa
Simão, Teresa São
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Mendes, Ana Raquel
Moreira, Liane
Dias, Ângela
Lopes, Andreia
Lobo, Ana Luísa
Simão, Teresa São
dc.subject.por.fl_str_mv Original Articles
topic Original Articles
description Introduction: Recurrent parotitis is defined as the occurrence of two or more episodes of the parotid gland. Several etiologies should be addressed in the approach to these patients. The aim of this study was to investigate the clinical, laboratory, and imaging profile of children with recurrent parotitis. Material and Methods: Retrospective review of the medical records of patients referred to a Pediatric Outpatient Clinic between January 2013 and June 2018.  Results: The medical records of 24 patients with recurrent parotitis (66.7% male) and a mean age of seven years and five months were reviewed. The median age of onset of episodes was five years and three months. Unilateral and non-febrile episodes prevailed. Non-steroidal anti-inflammatory drugs were universally used to treat symptoms. Non-acute parotid and neck ultrasound predominantly showed the presence of a heterogeneous gland (57.1%). Sialography performed in five patients suggested chronic parotitis in two and Sjögren syndrome/ sarcoidosis in one. No significant immunologic defects were found beside a mild C3 reduction in one patient and C4 reduction in another patient, apparently without clinical relevance. A single patient tested positive for antinuclear antibodies. Immunoglobulin A deficit was found in one case. The most common final diagnosis was juvenile recurrent parotitis (37.5%). Conclusions: Most cases of recurrent parotitis in pediatric age have benign etiology. A more judicious request of complementary exams in the acute and non-acute phases could be time- and cost-effective.
publishDate 2021
dc.date.none.fl_str_mv 2021-12-27T00:00:00Z
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dc.publisher.none.fl_str_mv Centro Hospitalar Universitário do Porto
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dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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