Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosis
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2022 |
| Outros Autores: | , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/148289 |
Resumo: | 54/2017). Publisher Copyright: © 2022 by the authors. |
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Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosiselectrodespoint-of-care methodscreening strategysyphilisTreponema pallidumPollutionPublic Health, Environmental and Occupational HealthHealth, Toxicology and MutagenesisSDG 3 - Good Health and Well-being54/2017). Publisher Copyright: © 2022 by the authors.The improvement of laboratory diagnosis is a critical step for the reduction of syphilis cases around the world. In this paper, we present the development of an impedance-based method for detecting T. pallidum antigens and antibodies as an auxiliary tool for syphilis laboratory diagnosis. We evaluate the voltammetric signal obtained after incubation in carbon or gold nanoparticle-modified carbon electrodes in the presence or absence of Poly-L-Lysine. Our results indicate that the signal obtained from the electrodes was sufficient to distinguish between infected and non-infected samples immediately (T0′) or 15 min (T15′) after incubation, indicating its potential use as a point-of-care method as a screening strategy.DEE - Departamento de Engenharia Electrotécnica e de ComputadoresRUNBarros, Gabriel M. C.Carvalho, Dionísio D. A.Cruz, Agnaldo S.Morais, Ellen K. L.Sales-Moioli, Ana Isabela L.Pinto, Talita K. B.Almeida, Melise C. D.Sanchez-Gendriz, IgnacioFernandes, FelipeBarbalho, Ingridy M. P.Santos, João P. Q.Henriques, Jorge M. O.Teixeira, César A. D.Gil, PauloGama, LúcioMiranda, Angélica E.Coutinho, Karilany D.Galvão-Lima, Leonardo J.Valentim, Ricardo A. M.2023-01-27T22:20:00Z2022-12-032022-12-03T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10application/pdfhttp://hdl.handle.net/10362/148289eng1661-7827PURE: 51478989https://doi.org/10.3390/ijerph192316206info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:29:42Zoai:run.unl.pt:10362/148289Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:53:18.833915Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosis |
| title |
Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosis |
| spellingShingle |
Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosis Barros, Gabriel M. C. electrodes point-of-care method screening strategy syphilis Treponema pallidum Pollution Public Health, Environmental and Occupational Health Health, Toxicology and Mutagenesis SDG 3 - Good Health and Well-being |
| title_short |
Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosis |
| title_full |
Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosis |
| title_fullStr |
Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosis |
| title_full_unstemmed |
Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosis |
| title_sort |
Development of a Cyclic Voltammetry-Based Method for the Detection of Antigens and Antibodies as a Novel Strategy for Syphilis Diagnosis |
| author |
Barros, Gabriel M. C. |
| author_facet |
Barros, Gabriel M. C. Carvalho, Dionísio D. A. Cruz, Agnaldo S. Morais, Ellen K. L. Sales-Moioli, Ana Isabela L. Pinto, Talita K. B. Almeida, Melise C. D. Sanchez-Gendriz, Ignacio Fernandes, Felipe Barbalho, Ingridy M. P. Santos, João P. Q. Henriques, Jorge M. O. Teixeira, César A. D. Gil, Paulo Gama, Lúcio Miranda, Angélica E. Coutinho, Karilany D. Galvão-Lima, Leonardo J. Valentim, Ricardo A. M. |
| author_role |
author |
| author2 |
Carvalho, Dionísio D. A. Cruz, Agnaldo S. Morais, Ellen K. L. Sales-Moioli, Ana Isabela L. Pinto, Talita K. B. Almeida, Melise C. D. Sanchez-Gendriz, Ignacio Fernandes, Felipe Barbalho, Ingridy M. P. Santos, João P. Q. Henriques, Jorge M. O. Teixeira, César A. D. Gil, Paulo Gama, Lúcio Miranda, Angélica E. Coutinho, Karilany D. Galvão-Lima, Leonardo J. Valentim, Ricardo A. M. |
| author2_role |
author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
DEE - Departamento de Engenharia Electrotécnica e de Computadores RUN |
| dc.contributor.author.fl_str_mv |
Barros, Gabriel M. C. Carvalho, Dionísio D. A. Cruz, Agnaldo S. Morais, Ellen K. L. Sales-Moioli, Ana Isabela L. Pinto, Talita K. B. Almeida, Melise C. D. Sanchez-Gendriz, Ignacio Fernandes, Felipe Barbalho, Ingridy M. P. Santos, João P. Q. Henriques, Jorge M. O. Teixeira, César A. D. Gil, Paulo Gama, Lúcio Miranda, Angélica E. Coutinho, Karilany D. Galvão-Lima, Leonardo J. Valentim, Ricardo A. M. |
| dc.subject.por.fl_str_mv |
electrodes point-of-care method screening strategy syphilis Treponema pallidum Pollution Public Health, Environmental and Occupational Health Health, Toxicology and Mutagenesis SDG 3 - Good Health and Well-being |
| topic |
electrodes point-of-care method screening strategy syphilis Treponema pallidum Pollution Public Health, Environmental and Occupational Health Health, Toxicology and Mutagenesis SDG 3 - Good Health and Well-being |
| description |
54/2017). Publisher Copyright: © 2022 by the authors. |
| publishDate |
2022 |
| dc.date.none.fl_str_mv |
2022-12-03 2022-12-03T00:00:00Z 2023-01-27T22:20:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/148289 |
| url |
http://hdl.handle.net/10362/148289 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
| dc.relation.none.fl_str_mv |
1661-7827 PURE: 51478989 https://doi.org/10.3390/ijerph192316206 |
| dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
| eu_rights_str_mv |
openAccess |
| dc.format.none.fl_str_mv |
10 application/pdf |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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