Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia

Detalhes bibliográficos
Autor(a) principal: Guedes, Renata R.
Data de Publicação: 2020
Outros Autores: Kieling, Carlos, Santos, Jorge Luiz dos, Rocha, Carolina da, Schwengber, Fernando, Adami, Marina R., Chedid, Marcio F., Vieira, Sandra M. G.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.6/9023
Resumo: Very few prior studies have investigated the presence of ascites as a prognostic factor in children with cirrhosis. To the best of our knowledge, there are no prior studies evaluating the relationship between severity of ascites and patient survival in children with biliary atresia and cirrhosis.Clinically detectable ascites is associated with decreased 1-year survival of children with biliary atresia. These patients should be treated with caution and prioritized for liver transplantation.
id RCAP_778bbf579ca544a0384ca1ddd88b7aea
oai_identifier_str oai:ubibliorum.ubi.pt:10400.6/9023
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary AtresiaAscitesChronic liver diseaseLiver transplantPediatric patientsPortal hypertensionSurvivalVery few prior studies have investigated the presence of ascites as a prognostic factor in children with cirrhosis. To the best of our knowledge, there are no prior studies evaluating the relationship between severity of ascites and patient survival in children with biliary atresia and cirrhosis.Clinically detectable ascites is associated with decreased 1-year survival of children with biliary atresia. These patients should be treated with caution and prioritized for liver transplantation.Background Very few prior studies have investigated the presence of ascites as a prognostic factor in children with cirrhosis. To the best of our knowledge, there are no prior studies evaluating the relationship between severity of ascites and patient survival in children with biliary atresia and cirrhosis. Aims To evaluate the association between severity of ascites and survival of children with cirrhosis and biliary atresia. Methods All children with cirrhosis secondary to biliary atresia evaluated at our institution from 2000 to 2014 were included in this study. Patients were classified into four groups: NA = no ascites; A1 = grade 1 ascites; A2 = grade 2 ascites; and A3 = grade 3 ascites. The primary endpoint of the study was mortality within the first year after patient inclusion. Ninetyday mortality was also evaluated. Prognostic factors related to both endpoints also were studied. [...]uBibliorumGuedes, Renata R.Kieling, CarlosSantos, Jorge Luiz dosRocha, Carolina daSchwengber, FernandoAdami, Marina R.Chedid, Marcio F.Vieira, Sandra M. G.2020-02-05T11:47:16Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/9023eng10.1007/s10620-019-06029-zinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-15T09:49:37Zoai:ubibliorum.ubi.pt:10400.6/9023Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:49:16.798422Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia
title Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia
spellingShingle Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia
Guedes, Renata R.
Ascites
Chronic liver disease
Liver transplant
Pediatric patients
Portal hypertension
Survival
title_short Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia
title_full Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia
title_fullStr Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia
title_full_unstemmed Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia
title_sort Severity of Ascites Is Associated with Increased Mortality in Patients with Cirrhosis Secondary to Biliary Atresia
author Guedes, Renata R.
author_facet Guedes, Renata R.
Kieling, Carlos
Santos, Jorge Luiz dos
Rocha, Carolina da
Schwengber, Fernando
Adami, Marina R.
Chedid, Marcio F.
Vieira, Sandra M. G.
author_role author
author2 Kieling, Carlos
Santos, Jorge Luiz dos
Rocha, Carolina da
Schwengber, Fernando
Adami, Marina R.
Chedid, Marcio F.
Vieira, Sandra M. G.
author2_role author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv uBibliorum
dc.contributor.author.fl_str_mv Guedes, Renata R.
Kieling, Carlos
Santos, Jorge Luiz dos
Rocha, Carolina da
Schwengber, Fernando
Adami, Marina R.
Chedid, Marcio F.
Vieira, Sandra M. G.
dc.subject.por.fl_str_mv Ascites
Chronic liver disease
Liver transplant
Pediatric patients
Portal hypertension
Survival
topic Ascites
Chronic liver disease
Liver transplant
Pediatric patients
Portal hypertension
Survival
description Very few prior studies have investigated the presence of ascites as a prognostic factor in children with cirrhosis. To the best of our knowledge, there are no prior studies evaluating the relationship between severity of ascites and patient survival in children with biliary atresia and cirrhosis.Clinically detectable ascites is associated with decreased 1-year survival of children with biliary atresia. These patients should be treated with caution and prioritized for liver transplantation.
publishDate 2020
dc.date.none.fl_str_mv 2020-02-05T11:47:16Z
2020
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.6/9023
url http://hdl.handle.net/10400.6/9023
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1007/s10620-019-06029-z
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799136385267924992

Registros relacionados