Chemically modified electrodes for the detection of antidepressants

• Autor(a) principal: Caldevilla, Renato
• Data de Publicação: 2023
• Outros Autores: Morais, Stephanie L., Cruz, Agostinho, Delerue-Matos, Cristina, Moreira, Fernando, Pacheco, João G., Santos, Marlene, Barroso, Maria Fátima
• Tipo de documento: Artigo
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://hdl.handle.net/10400.22/23275
• topic: Antidepressants; Chemically modified electrodes; Electrochemical biosensor

Major depressive disorder is a widespread condition with antidepressants as the main pharmacological treatment. However, some patients experience concerning adverse reactions or have an inadequate response to treatment. Analytical chromatographic techniques, among other techniques, are valuable tools for investigating medication complications, including those associated with antidepressants. Nevertheless, there is a growing need to address the limitations associated with these techniques. In recent years, electrochemical (bio)sensors have garnered significant attention due to their lower cost, portability, and precision. Electrochemical (bio)sensors can be used for various applications related to depression, such as monitoring the levels of antidepressants in biological and in environmental samples. They can provide accurate and rapid results, which could facilitate personalized treatment and improve patient outcomes.