Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case Report

Detalhes bibliográficos
Autor(a) principal: Medeiros Prohmann, Caroline
Data de Publicação: 2018
Outros Autores: de Araújo Dantas, Camila, Barcelos e Silva, Lorena, Figueiredo Gatti, Rafael, Marçal Machado, Thalita, Antônio, João Roberto
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.29021/spdv.75.3.818
Resumo: Paracoccidioidomycosis (also known as Lutz disease, Lutz-Splendore-Almeida disease, Brazilian blastomycosis or South American blastomycosis) was first described by Lutz nearly a century ago. This is a systemic fungal infection that can appear in two clinical forms: acute / subacute or chronic. Oral lesions of paracoccidioidomycosis are typically characterized by erythematous and finely granular gingival hyperplasia with petechiae. Additionally, shallow ulcers with microgranulations and pinpoint hemorrhages may involve the lips, jugal mucosa, palate, tonsillar pillars and tongue. Lesions have a mulberry-like surface called "moriform stomatitis". Although common, these lesions are under diagnosed and the late recognition of this disease may lead to rapid progression, and death. We report the case of a young patient with generalized lymphadenopathy, moriform stomatitis and constitutional symptoms (fever, weight loss). We emphasize the importance of the dermatologist in the early identification of the cutaneous-mucous lesions typical of paracoccidioidomycosis and in the establishment of an accurate diagnosis.
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spelling Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case ReportParacoccidioidomicose com Acometimento Ganglionar e Mucoso - Relato de CasoParacoccidioidomycosisStomatitis.ParacoccidioidomicoseEstomatiteParacoccidioidomycosis (also known as Lutz disease, Lutz-Splendore-Almeida disease, Brazilian blastomycosis or South American blastomycosis) was first described by Lutz nearly a century ago. This is a systemic fungal infection that can appear in two clinical forms: acute / subacute or chronic. Oral lesions of paracoccidioidomycosis are typically characterized by erythematous and finely granular gingival hyperplasia with petechiae. Additionally, shallow ulcers with microgranulations and pinpoint hemorrhages may involve the lips, jugal mucosa, palate, tonsillar pillars and tongue. Lesions have a mulberry-like surface called "moriform stomatitis". Although common, these lesions are under diagnosed and the late recognition of this disease may lead to rapid progression, and death. We report the case of a young patient with generalized lymphadenopathy, moriform stomatitis and constitutional symptoms (fever, weight loss). We emphasize the importance of the dermatologist in the early identification of the cutaneous-mucous lesions typical of paracoccidioidomycosis and in the establishment of an accurate diagnosis.A paracoccidioidomicose (também conhecida como doença de Lutz, doença de Lutz-Splendore-Almeida, blastomicose Brasileira ou blastomicose Sul Americana) foi inicialmente descrita por Lutz há quase um século. Trata-se de uma infecção fúngica sistémica, que pode apresentar-se sob duas formas clínicas: aguda/subaguda ou crónica. As lesões orais da paracoccidioidomicose são tipicamente caracterizadas por hiperplasia gengival eritematosa e finamente granular, com petéquias. Além disso, observam-se úlceras superficiais com micro granulações e ponteados hemorrágicos, que podem envolver lábios, mucosa jugal, palato, pilares amigdalianos e língua. A superfície é semelhante à amora sendo por isso denominada de “estomatite moriforme”. Apesar de comuns, essas lesões são subdiagnosticadas e o reconhecimento tardio desta patologia pode levar à rápida progressão do quadro clínico, por vezes com desfecho fatal. Relatamos o caso de um paciente jovem com adenopatias generalizadas, estomatite moriforme e sintomas constitucionais (febre, perda de peso). Destaca-se a importância do dermatologista na identificação precoce das lesões cutaneomucosas típicas da paracoccidioidomicose e no estabelecimento de um diagnóstico preciso.Sociedade Portuguesa de Dermatologia e Venereologia2018-01-22T00:00:00Zjournal articleinfo:eu-repo/semantics/articleinfo:eu-repo/semantics/publishedVersionapplication/pdfhttps://doi.org/10.29021/spdv.75.3.818oai:ojs.revista.spdv.com.pt:article/818Journal of the Portuguese Society of Dermatology and Venereology; Vol 75 No 3 (2017): Julho - Setembro; 283-287Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 75 n. 3 (2017): Julho - Setembro; 283-2872182-24092182-2395reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://revista.spdv.com.pt/index.php/spdv/article/view/818https://doi.org/10.29021/spdv.75.3.818https://revista.spdv.com.pt/index.php/spdv/article/view/818/513Medeiros Prohmann, Carolinede Araújo Dantas, CamilaBarcelos e Silva, LorenaFigueiredo Gatti, RafaelMarçal Machado, ThalitaAntônio, João Robertoinfo:eu-repo/semantics/openAccess2022-10-06T12:35:04Zoai:ojs.revista.spdv.com.pt:article/818Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:11:03.941408Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case Report
Paracoccidioidomicose com Acometimento Ganglionar e Mucoso - Relato de Caso
title Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case Report
spellingShingle Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case Report
Medeiros Prohmann, Caroline
Paracoccidioidomycosis
Stomatitis.
Paracoccidioidomicose
Estomatite
title_short Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case Report
title_full Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case Report
title_fullStr Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case Report
title_full_unstemmed Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case Report
title_sort Paracoccidioidomycosis with Lymphonodal and Mucous Involvement - Case Report
author Medeiros Prohmann, Caroline
author_facet Medeiros Prohmann, Caroline
de Araújo Dantas, Camila
Barcelos e Silva, Lorena
Figueiredo Gatti, Rafael
Marçal Machado, Thalita
Antônio, João Roberto
author_role author
author2 de Araújo Dantas, Camila
Barcelos e Silva, Lorena
Figueiredo Gatti, Rafael
Marçal Machado, Thalita
Antônio, João Roberto
author2_role author
author
author
author
author
dc.contributor.author.fl_str_mv Medeiros Prohmann, Caroline
de Araújo Dantas, Camila
Barcelos e Silva, Lorena
Figueiredo Gatti, Rafael
Marçal Machado, Thalita
Antônio, João Roberto
dc.subject.por.fl_str_mv Paracoccidioidomycosis
Stomatitis.
Paracoccidioidomicose
Estomatite
topic Paracoccidioidomycosis
Stomatitis.
Paracoccidioidomicose
Estomatite
description Paracoccidioidomycosis (also known as Lutz disease, Lutz-Splendore-Almeida disease, Brazilian blastomycosis or South American blastomycosis) was first described by Lutz nearly a century ago. This is a systemic fungal infection that can appear in two clinical forms: acute / subacute or chronic. Oral lesions of paracoccidioidomycosis are typically characterized by erythematous and finely granular gingival hyperplasia with petechiae. Additionally, shallow ulcers with microgranulations and pinpoint hemorrhages may involve the lips, jugal mucosa, palate, tonsillar pillars and tongue. Lesions have a mulberry-like surface called "moriform stomatitis". Although common, these lesions are under diagnosed and the late recognition of this disease may lead to rapid progression, and death. We report the case of a young patient with generalized lymphadenopathy, moriform stomatitis and constitutional symptoms (fever, weight loss). We emphasize the importance of the dermatologist in the early identification of the cutaneous-mucous lesions typical of paracoccidioidomycosis and in the establishment of an accurate diagnosis.
publishDate 2018
dc.date.none.fl_str_mv 2018-01-22T00:00:00Z
dc.type.driver.fl_str_mv journal article
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dc.identifier.uri.fl_str_mv https://doi.org/10.29021/spdv.75.3.818
oai:ojs.revista.spdv.com.pt:article/818
url https://doi.org/10.29021/spdv.75.3.818
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dc.relation.none.fl_str_mv https://revista.spdv.com.pt/index.php/spdv/article/view/818
https://doi.org/10.29021/spdv.75.3.818
https://revista.spdv.com.pt/index.php/spdv/article/view/818/513
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
publisher.none.fl_str_mv Sociedade Portuguesa de Dermatologia e Venereologia
dc.source.none.fl_str_mv Journal of the Portuguese Society of Dermatology and Venereology; Vol 75 No 3 (2017): Julho - Setembro; 283-287
Revista da Sociedade Portuguesa de Dermatologia e Venereologia; v. 75 n. 3 (2017): Julho - Setembro; 283-287
2182-2409
2182-2395
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