The relations between neurocognition and quality of life in people with schizophrenia.
Autor(a) principal: | |
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Data de Publicação: | 2009 |
Outros Autores: | , , , |
Tipo de documento: | Artigo |
Idioma: | por |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1682 |
Resumo: | Neurocognitive deficits constitute an important and significant characteristic of Schizophrenia. Recent investigations tried to establish a causal relationship between neurocognitive deficits and functional outcomes. However, in studies that used quality of life as the primary functional variable, mixed results were found. In some studies associations with neurocognition were strong, but in others, the associations were week or inexistent. The purpose of this study was to identify neurocognitive constructs that seems to be differential predictors of distinct quality of life dimensions. Sample consisted of 37 individuals diagnosed with Schizophrenia. All subjects were assessed with a battery of neurocognitive tests. For the assessment of quality of life we used the WHOQOL--Bref Portuguese Version. We performed correlational analysis and stepwise multiple regression analysis, in order to determine predictive models of quality of life. There were found significant correlations between most of the neurocognitive constructs and quality of life. Predictive models explained 21% to 49% of the variance in the domains of quality of life that we considered. Significant neurocognitive predictors were the following: for the Physical domain, the executive functions; for the Psychological and Social Relations domains, attention and visual-spatial organization; for the Environmental domain, the executive functions and attention. These results highlight the significance of basic neurocognitive functions to the determination of quality of life outcomes in persons with Schizophrenia, especially the functions related to the ability to adapt to changes and to the environmental feedback, the ability to keep focused and attentive, and the aptitude to correctly organize perceptual data. |
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The relations between neurocognition and quality of life in people with schizophrenia.Relação entre neurocognição e qualidade de vida em pessoas com esquizofrenia.Neurocognitive deficits constitute an important and significant characteristic of Schizophrenia. Recent investigations tried to establish a causal relationship between neurocognitive deficits and functional outcomes. However, in studies that used quality of life as the primary functional variable, mixed results were found. In some studies associations with neurocognition were strong, but in others, the associations were week or inexistent. The purpose of this study was to identify neurocognitive constructs that seems to be differential predictors of distinct quality of life dimensions. Sample consisted of 37 individuals diagnosed with Schizophrenia. All subjects were assessed with a battery of neurocognitive tests. For the assessment of quality of life we used the WHOQOL--Bref Portuguese Version. We performed correlational analysis and stepwise multiple regression analysis, in order to determine predictive models of quality of life. There were found significant correlations between most of the neurocognitive constructs and quality of life. Predictive models explained 21% to 49% of the variance in the domains of quality of life that we considered. Significant neurocognitive predictors were the following: for the Physical domain, the executive functions; for the Psychological and Social Relations domains, attention and visual-spatial organization; for the Environmental domain, the executive functions and attention. These results highlight the significance of basic neurocognitive functions to the determination of quality of life outcomes in persons with Schizophrenia, especially the functions related to the ability to adapt to changes and to the environmental feedback, the ability to keep focused and attentive, and the aptitude to correctly organize perceptual data.Neurocognitive deficits constitute an important and significant characteristic of Schizophrenia. Recent investigations tried to establish a causal relationship between neurocognitive deficits and functional outcomes. However, in studies that used quality of life as the primary functional variable, mixed results were found. In some studies associations with neurocognition were strong, but in others, the associations were week or inexistent. The purpose of this study was to identify neurocognitive constructs that seems to be differential predictors of distinct quality of life dimensions. Sample consisted of 37 individuals diagnosed with Schizophrenia. All subjects were assessed with a battery of neurocognitive tests. For the assessment of quality of life we used the WHOQOL--Bref Portuguese Version. We performed correlational analysis and stepwise multiple regression analysis, in order to determine predictive models of quality of life. There were found significant correlations between most of the neurocognitive constructs and quality of life. Predictive models explained 21% to 49% of the variance in the domains of quality of life that we considered. Significant neurocognitive predictors were the following: for the Physical domain, the executive functions; for the Psychological and Social Relations domains, attention and visual-spatial organization; for the Environmental domain, the executive functions and attention. These results highlight the significance of basic neurocognitive functions to the determination of quality of life outcomes in persons with Schizophrenia, especially the functions related to the ability to adapt to changes and to the environmental feedback, the ability to keep focused and attentive, and the aptitude to correctly organize perceptual data.Ordem dos Médicos2009-02-27info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1682oai:ojs.www.actamedicaportuguesa.com:article/1682Acta Médica Portuguesa; Vol. 22 No. 1 (2009): Janeiro-Fevereiro; 71-82Acta Médica Portuguesa; Vol. 22 N.º 1 (2009): Janeiro-Fevereiro; 71-821646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1682https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1682/1262Rocha, NunoQueirós, CristinaAguiar, SusanaMarques, AntónioHorta, Maria Purificaçãoinfo:eu-repo/semantics/openAccess2022-12-20T10:58:31Zoai:ojs.www.actamedicaportuguesa.com:article/1682Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:17:18.758425Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
The relations between neurocognition and quality of life in people with schizophrenia. Relação entre neurocognição e qualidade de vida em pessoas com esquizofrenia. |
title |
The relations between neurocognition and quality of life in people with schizophrenia. |
spellingShingle |
The relations between neurocognition and quality of life in people with schizophrenia. Rocha, Nuno |
title_short |
The relations between neurocognition and quality of life in people with schizophrenia. |
title_full |
The relations between neurocognition and quality of life in people with schizophrenia. |
title_fullStr |
The relations between neurocognition and quality of life in people with schizophrenia. |
title_full_unstemmed |
The relations between neurocognition and quality of life in people with schizophrenia. |
title_sort |
The relations between neurocognition and quality of life in people with schizophrenia. |
author |
Rocha, Nuno |
author_facet |
Rocha, Nuno Queirós, Cristina Aguiar, Susana Marques, António Horta, Maria Purificação |
author_role |
author |
author2 |
Queirós, Cristina Aguiar, Susana Marques, António Horta, Maria Purificação |
author2_role |
author author author author |
dc.contributor.author.fl_str_mv |
Rocha, Nuno Queirós, Cristina Aguiar, Susana Marques, António Horta, Maria Purificação |
description |
Neurocognitive deficits constitute an important and significant characteristic of Schizophrenia. Recent investigations tried to establish a causal relationship between neurocognitive deficits and functional outcomes. However, in studies that used quality of life as the primary functional variable, mixed results were found. In some studies associations with neurocognition were strong, but in others, the associations were week or inexistent. The purpose of this study was to identify neurocognitive constructs that seems to be differential predictors of distinct quality of life dimensions. Sample consisted of 37 individuals diagnosed with Schizophrenia. All subjects were assessed with a battery of neurocognitive tests. For the assessment of quality of life we used the WHOQOL--Bref Portuguese Version. We performed correlational analysis and stepwise multiple regression analysis, in order to determine predictive models of quality of life. There were found significant correlations between most of the neurocognitive constructs and quality of life. Predictive models explained 21% to 49% of the variance in the domains of quality of life that we considered. Significant neurocognitive predictors were the following: for the Physical domain, the executive functions; for the Psychological and Social Relations domains, attention and visual-spatial organization; for the Environmental domain, the executive functions and attention. These results highlight the significance of basic neurocognitive functions to the determination of quality of life outcomes in persons with Schizophrenia, especially the functions related to the ability to adapt to changes and to the environmental feedback, the ability to keep focused and attentive, and the aptitude to correctly organize perceptual data. |
publishDate |
2009 |
dc.date.none.fl_str_mv |
2009-02-27 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
format |
article |
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publishedVersion |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1682 oai:ojs.www.actamedicaportuguesa.com:article/1682 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1682 |
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oai:ojs.www.actamedicaportuguesa.com:article/1682 |
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por |
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por |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1682 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1682/1262 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
dc.publisher.none.fl_str_mv |
Ordem dos Médicos |
publisher.none.fl_str_mv |
Ordem dos Médicos |
dc.source.none.fl_str_mv |
Acta Médica Portuguesa; Vol. 22 No. 1 (2009): Janeiro-Fevereiro; 71-82 Acta Médica Portuguesa; Vol. 22 N.º 1 (2009): Janeiro-Fevereiro; 71-82 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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