Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report

Detalhes bibliográficos
Autor(a) principal: Jafry,Nazrul Hassan
Data de Publicação: 2019
Outros Autores: Mubarak,Muhammad, Anis,Sabiha, Ahmed,Ejaz, Akhtar,Fazal
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200009
Resumo: We report a case of myeloma-like cast nephropathy in a 27-year-old male patient with human immunodeficiency virus (HIV) infection for 2 years. He was on highly active anti-retroviral therapy (HAART) and presented with high grade fever, nausea and vomiting for 2 weeks. On investigations, he was found to have acute kidney injury (AKI). He was started on hemodialysis. Renal biopsy revealed acute tubulointerstitial nephritis with myeloma-like casts in a few tubular lumens. Detailed workup for multiple myeloma was negative. No evidence of monoclonal gammopathy was found. Finally, he was diagnosed as a case of myeloma-like cast nephropathy. With supportive treatment and modification in HAART therapy, his renal functions improved and he became dialysis free in 2 weeks. He was continued on HAART therapy, but he soon discontinued this against medical advice.
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spelling Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case reportMyeloma castsacute tubular injuryHIVanti-retroviral therapyWe report a case of myeloma-like cast nephropathy in a 27-year-old male patient with human immunodeficiency virus (HIV) infection for 2 years. He was on highly active anti-retroviral therapy (HAART) and presented with high grade fever, nausea and vomiting for 2 weeks. On investigations, he was found to have acute kidney injury (AKI). He was started on hemodialysis. Renal biopsy revealed acute tubulointerstitial nephritis with myeloma-like casts in a few tubular lumens. Detailed workup for multiple myeloma was negative. No evidence of monoclonal gammopathy was found. Finally, he was diagnosed as a case of myeloma-like cast nephropathy. With supportive treatment and modification in HAART therapy, his renal functions improved and he became dialysis free in 2 weeks. He was continued on HAART therapy, but he soon discontinued this against medical advice.Sociedade Portuguesa de Nefrologia2019-06-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200009Portuguese Journal of Nephrology & Hypertension v.33 n.2 2019reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200009Jafry,Nazrul HassanMubarak,MuhammadAnis,SabihaAhmed,EjazAkhtar,Fazalinfo:eu-repo/semantics/openAccess2024-02-06T17:05:02Zoai:scielo:S0872-01692019000200009Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:19:02.438245Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
spellingShingle Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
Jafry,Nazrul Hassan
Myeloma casts
acute tubular injury
HIV
anti-retroviral therapy
title_short Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title_full Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title_fullStr Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title_full_unstemmed Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
title_sort Myeloma-like cast nephropathy in a human immunodeficiency virus infected patient: a case report
author Jafry,Nazrul Hassan
author_facet Jafry,Nazrul Hassan
Mubarak,Muhammad
Anis,Sabiha
Ahmed,Ejaz
Akhtar,Fazal
author_role author
author2 Mubarak,Muhammad
Anis,Sabiha
Ahmed,Ejaz
Akhtar,Fazal
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Jafry,Nazrul Hassan
Mubarak,Muhammad
Anis,Sabiha
Ahmed,Ejaz
Akhtar,Fazal
dc.subject.por.fl_str_mv Myeloma casts
acute tubular injury
HIV
anti-retroviral therapy
topic Myeloma casts
acute tubular injury
HIV
anti-retroviral therapy
description We report a case of myeloma-like cast nephropathy in a 27-year-old male patient with human immunodeficiency virus (HIV) infection for 2 years. He was on highly active anti-retroviral therapy (HAART) and presented with high grade fever, nausea and vomiting for 2 weeks. On investigations, he was found to have acute kidney injury (AKI). He was started on hemodialysis. Renal biopsy revealed acute tubulointerstitial nephritis with myeloma-like casts in a few tubular lumens. Detailed workup for multiple myeloma was negative. No evidence of monoclonal gammopathy was found. Finally, he was diagnosed as a case of myeloma-like cast nephropathy. With supportive treatment and modification in HAART therapy, his renal functions improved and he became dialysis free in 2 weeks. He was continued on HAART therapy, but he soon discontinued this against medical advice.
publishDate 2019
dc.date.none.fl_str_mv 2019-06-01
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format report
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dc.identifier.uri.fl_str_mv http://scielo.pt/scielo.php?script=sci_arttext&pid=S0872-01692019000200009
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dc.language.iso.fl_str_mv eng
language eng
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dc.publisher.none.fl_str_mv Sociedade Portuguesa de Nefrologia
publisher.none.fl_str_mv Sociedade Portuguesa de Nefrologia
dc.source.none.fl_str_mv Portuguese Journal of Nephrology & Hypertension v.33 n.2 2019
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
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repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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