Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRI

Detalhes bibliográficos
Autor(a) principal: Amado, Catarina Pereira
Data de Publicação: 2014
Tipo de documento: Dissertação
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/13161
Resumo: Dissertação para a obtenção do Grau de Mestre em Engenharia Biomédica
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spelling Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRIPrimary motor cortexHigh-resolution fMRIFingers organizationMotor imageryMovement observationCortical columnsDissertação para a obtenção do Grau de Mestre em Engenharia BiomédicaHuman behaviour is grounded in our ability to perform complex tasks. While human motor function has been studied for over a century the cortical processes underlying motor behaviour are still under debate. Central to the execution of action is the primary motor cortex (M1), which has previously been considered to be responsible for the execution of movements planned in the premotor cortex, yet recent studies point to more complex roles for M1 in orchestrating motor-related information. The purpose of this project is to study the functional properties of primary motor cortex using ultra-high fMRI. The spatial resolution made possible by using a high field magnet allows us to investigate novel questions such as the existence of cortical columns, the functional organization pattern for single fingers and functional involvement of M1 in motor imagery and observation. Thirteen young healthy subjects participated in this study. Functional and anatomical high resolution images were acquired. Four functional scans were acquired for the different tasks: motor execution; motor imagery; movement observation and rest. The paradigm used was a randomized finger tapping. The images analysis was performed with the Brainvoyager QX program. Using the novel high resolution cortical grid sampling analysis tools, different cortical laminas of human M1 were examined. Our results reveal a distributed pattern (intermingled with somatotopic “hot spots”) for single fingers activity in M1. Furthermore we show novel evidence of columnar structures in M1 and show that non motor tasks such as motor imagery and action observation also activate this region. We conclude that the primary motor cortex has much more un-expected complex roles regarding the processing of movement related information, not only due to their involvement in tasks that do not imply muscle movement, but also due to their intriguing organization pattern.Faculdade de Ciências e TecnologiaZwaag, WietskeSalomon, RoySecca, MárioRUNAmado, Catarina Pereira2014-10-01T10:47:35Z20142014-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10362/13161enginfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T03:47:56Zoai:run.unl.pt:10362/13161Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:21:07.518703Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRI
title Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRI
spellingShingle Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRI
Amado, Catarina Pereira
Primary motor cortex
High-resolution fMRI
Fingers organization
Motor imagery
Movement observation
Cortical columns
title_short Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRI
title_full Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRI
title_fullStr Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRI
title_full_unstemmed Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRI
title_sort Diving into the depth of primary motor cortex: a high-resolution investigation of the motor system using 7Tesla fMRI
author Amado, Catarina Pereira
author_facet Amado, Catarina Pereira
author_role author
dc.contributor.none.fl_str_mv Zwaag, Wietske
Salomon, Roy
Secca, Mário
RUN
dc.contributor.author.fl_str_mv Amado, Catarina Pereira
dc.subject.por.fl_str_mv Primary motor cortex
High-resolution fMRI
Fingers organization
Motor imagery
Movement observation
Cortical columns
topic Primary motor cortex
High-resolution fMRI
Fingers organization
Motor imagery
Movement observation
Cortical columns
description Dissertação para a obtenção do Grau de Mestre em Engenharia Biomédica
publishDate 2014
dc.date.none.fl_str_mv 2014-10-01T10:47:35Z
2014
2014-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/13161
url http://hdl.handle.net/10362/13161
dc.language.iso.fl_str_mv eng
language eng
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Faculdade de Ciências e Tecnologia
publisher.none.fl_str_mv Faculdade de Ciências e Tecnologia
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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