Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010

Detalhes bibliográficos
Autor(a) principal: Oliveira, CM
Data de Publicação: 2020
Outros Autores: Teixeira, H, Alves, SM, Pina, MF
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/145257
Resumo: Geographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Discharge Register we selected admissions of patients aged =50 years, diagnosed with HF caused by low/moderate energy traumas. Water components and characteristics were selected at themunicipality level. A spatial generalized additive model with a negative binomial distribution as a link function was used to estimate the association of HF with variations in DWC. There were 96,905HF (77.3% in women). The spatial pattern of HF risk was attenuated after being adjusted for water parameters. Results show an indirect association between calcium, magnesium, and iron and HF risk but no clear relation between aluminum, cadmium, fluoride, manganese, or color and HF risk. Regarding pH, the 6.7pH and 7pH interval seems to pose a lower risk. Different dose-response relationships were identified. The increase of calcium, magnesium, and iron values in DWC seems to reduce regional HF risk. Long-term exposure to water parameters, even within the regulatory limits, might increase the regional HF risk.
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spelling Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010DrinkingWaterCompositionHipFractureHospital AdmissionsSpatial EpidemiologyGeographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Discharge Register we selected admissions of patients aged =50 years, diagnosed with HF caused by low/moderate energy traumas. Water components and characteristics were selected at themunicipality level. A spatial generalized additive model with a negative binomial distribution as a link function was used to estimate the association of HF with variations in DWC. There were 96,905HF (77.3% in women). The spatial pattern of HF risk was attenuated after being adjusted for water parameters. Results show an indirect association between calcium, magnesium, and iron and HF risk but no clear relation between aluminum, cadmium, fluoride, manganese, or color and HF risk. Regarding pH, the 6.7pH and 7pH interval seems to pose a lower risk. Different dose-response relationships were identified. The increase of calcium, magnesium, and iron values in DWC seems to reduce regional HF risk. Long-term exposure to water parameters, even within the regulatory limits, might increase the regional HF risk.20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/145257eng0104-129010.1590/s0104-12902020200094Oliveira, CMTeixeira, HAlves, SMPina, MFinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T13:16:12Zoai:repositorio-aberto.up.pt:10216/145257Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:37:07.467564Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
title Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
spellingShingle Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
Oliveira, CM
DrinkingWaterComposition
HipFracture
Hospital Admissions
Spatial Epidemiology
title_short Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
title_full Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
title_fullStr Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
title_full_unstemmed Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
title_sort Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
author Oliveira, CM
author_facet Oliveira, CM
Teixeira, H
Alves, SM
Pina, MF
author_role author
author2 Teixeira, H
Alves, SM
Pina, MF
author2_role author
author
author
dc.contributor.author.fl_str_mv Oliveira, CM
Teixeira, H
Alves, SM
Pina, MF
dc.subject.por.fl_str_mv DrinkingWaterComposition
HipFracture
Hospital Admissions
Spatial Epidemiology
topic DrinkingWaterComposition
HipFracture
Hospital Admissions
Spatial Epidemiology
description Geographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Discharge Register we selected admissions of patients aged =50 years, diagnosed with HF caused by low/moderate energy traumas. Water components and characteristics were selected at themunicipality level. A spatial generalized additive model with a negative binomial distribution as a link function was used to estimate the association of HF with variations in DWC. There were 96,905HF (77.3% in women). The spatial pattern of HF risk was attenuated after being adjusted for water parameters. Results show an indirect association between calcium, magnesium, and iron and HF risk but no clear relation between aluminum, cadmium, fluoride, manganese, or color and HF risk. Regarding pH, the 6.7pH and 7pH interval seems to pose a lower risk. Different dose-response relationships were identified. The increase of calcium, magnesium, and iron values in DWC seems to reduce regional HF risk. Long-term exposure to water parameters, even within the regulatory limits, might increase the regional HF risk.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
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url https://hdl.handle.net/10216/145257
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0104-1290
10.1590/s0104-12902020200094
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