Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/10216/145257 |
Resumo: | Geographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Discharge Register we selected admissions of patients aged =50 years, diagnosed with HF caused by low/moderate energy traumas. Water components and characteristics were selected at themunicipality level. A spatial generalized additive model with a negative binomial distribution as a link function was used to estimate the association of HF with variations in DWC. There were 96,905HF (77.3% in women). The spatial pattern of HF risk was attenuated after being adjusted for water parameters. Results show an indirect association between calcium, magnesium, and iron and HF risk but no clear relation between aluminum, cadmium, fluoride, manganese, or color and HF risk. Regarding pH, the 6.7pH and 7pH interval seems to pose a lower risk. Different dose-response relationships were identified. The increase of calcium, magnesium, and iron values in DWC seems to reduce regional HF risk. Long-term exposure to water parameters, even within the regulatory limits, might increase the regional HF risk. |
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Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010DrinkingWaterCompositionHipFractureHospital AdmissionsSpatial EpidemiologyGeographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Discharge Register we selected admissions of patients aged =50 years, diagnosed with HF caused by low/moderate energy traumas. Water components and characteristics were selected at themunicipality level. A spatial generalized additive model with a negative binomial distribution as a link function was used to estimate the association of HF with variations in DWC. There were 96,905HF (77.3% in women). The spatial pattern of HF risk was attenuated after being adjusted for water parameters. Results show an indirect association between calcium, magnesium, and iron and HF risk but no clear relation between aluminum, cadmium, fluoride, manganese, or color and HF risk. Regarding pH, the 6.7pH and 7pH interval seems to pose a lower risk. Different dose-response relationships were identified. The increase of calcium, magnesium, and iron values in DWC seems to reduce regional HF risk. Long-term exposure to water parameters, even within the regulatory limits, might increase the regional HF risk.20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/145257eng0104-129010.1590/s0104-12902020200094Oliveira, CMTeixeira, HAlves, SMPina, MFinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T13:16:12Zoai:repositorio-aberto.up.pt:10216/145257Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T23:37:07.467564Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
title |
Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
spellingShingle |
Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 Oliveira, CM DrinkingWaterComposition HipFracture Hospital Admissions Spatial Epidemiology |
title_short |
Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
title_full |
Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
title_fullStr |
Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
title_full_unstemmed |
Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
title_sort |
Regional drinking water composition effects on hip fracture risk: A spatial analysis of nationwide hospital admissions in Portugal, from 2000 to 2010 |
author |
Oliveira, CM |
author_facet |
Oliveira, CM Teixeira, H Alves, SM Pina, MF |
author_role |
author |
author2 |
Teixeira, H Alves, SM Pina, MF |
author2_role |
author author author |
dc.contributor.author.fl_str_mv |
Oliveira, CM Teixeira, H Alves, SM Pina, MF |
dc.subject.por.fl_str_mv |
DrinkingWaterComposition HipFracture Hospital Admissions Spatial Epidemiology |
topic |
DrinkingWaterComposition HipFracture Hospital Admissions Spatial Epidemiology |
description |
Geographical variation on hip fractures (HF) may be related to the geographical variation of drinking water composition (DWC); minerals in drinking water may contribute to its fragility. We aim to investigate the effects of DWC on HF risk in Portugal (2000-2010). From National Hospital Discharge Register we selected admissions of patients aged =50 years, diagnosed with HF caused by low/moderate energy traumas. Water components and characteristics were selected at themunicipality level. A spatial generalized additive model with a negative binomial distribution as a link function was used to estimate the association of HF with variations in DWC. There were 96,905HF (77.3% in women). The spatial pattern of HF risk was attenuated after being adjusted for water parameters. Results show an indirect association between calcium, magnesium, and iron and HF risk but no clear relation between aluminum, cadmium, fluoride, manganese, or color and HF risk. Regarding pH, the 6.7pH and 7pH interval seems to pose a lower risk. Different dose-response relationships were identified. The increase of calcium, magnesium, and iron values in DWC seems to reduce regional HF risk. Long-term exposure to water parameters, even within the regulatory limits, might increase the regional HF risk. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/10216/145257 |
url |
https://hdl.handle.net/10216/145257 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
0104-1290 10.1590/s0104-12902020200094 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799135684077813761 |