Identification of clusters of asthma control: A preliminary analysis of the inspirers studies
| Autor(a) principal: | |
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| Data de Publicação: | 2020 |
| Outros Autores: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | http://hdl.handle.net/10362/113596 |
Resumo: | This work was funded by ERDF (European Regional Development Fund) through the operations: POCI- -01-0145-FEDER-029130 (“mINSPIRERS—mHealth to measure and improve adherence to medication in chronic obstructive respiratory diseases - generalisation and evaluation of gamification, peer support and advanced image processing technologies”) co-funded by the COMPETE2020 (Programa Operacional Competitividade e Internacionalização), Portugal 2020 and by Portuguese Funds through FCT (Fundação para a Ciência e a Tecnologia). |
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Identification of clusters of asthma control: A preliminary analysis of the inspirers studiesAsthmaAsthma controlClassificationCluster analysisControl of allergic rhinitis and asthma testThis work was funded by ERDF (European Regional Development Fund) through the operations: POCI- -01-0145-FEDER-029130 (“mINSPIRERS—mHealth to measure and improve adherence to medication in chronic obstructive respiratory diseases - generalisation and evaluation of gamification, peer support and advanced image processing technologies”) co-funded by the COMPETE2020 (Programa Operacional Competitividade e Internacionalização), Portugal 2020 and by Portuguese Funds through FCT (Fundação para a Ciência e a Tecnologia).© 2020, Sociedade Portuguesa de Alergologia e Imunologia Clinica. All rights reserved. Aims: To identify distinct asthma control clusters based on Control of Allergic Rhinitis and Asthma Test (CARAT) and to compare patients’ characteristics among these clusters. Methods: Adults and adolescents (≥13 years) with persistent asthma were recruited at 29 Portuguese hospital outpatient clinics, in the context of two observational studies of the INSPIRERS project. Demographic and clinical characteristics, adherence to inhaled medication, beliefs about inhaled medication, anxiety and depression, quality of life, and asthma control (CARAT, >24 good control) were collected. Hierarchical cluster analysis was performed using CARAT total score (CARAT-T). Results: 410 patients (68% adults), with a median (percentile 25–percentile 75) age of 28 (16-46) years, were analysed. Three clusters were identified [mean CARAT-T (min-max)]: cluster 1 [27(24-30)], cluster 2 [19(14-23)] and cluster 3 [10(2-13)]. Patients in cluster 1 (34%) were characterised by better asthma control, better quality of life, higher inhaler adherence and use of a single inhaler. Patients in clusters 2 (50%) and 3 (16%) had uncontrolled asthma, lower inhaler adherence, more symptoms of anxiety and depression and more than half had at least one exacerbation in the previous year. Further-more, patients in cluster 3 were predominantly female, had more unscheduled medical visits and more anxiety symp-toms, perceived a higher necessity of their prescribed inhalers but also higher levels of concern about taking these inhalers. There were no differences in age, body mass index, lung function, smoking status, hospital admissions or specialist physician follow-up time among the three clusters. Conclusion: An unsupervised method based on CARAT--T, identified 3 clusters of patients with distinct, clinically meaningful characteristics. The cluster with better asthma control had a cut-off similar to the established in the validation study of CARAT and an additional cut-off seems to distinguish more severe disease. Further research is necessary to validate the asthma control clusters identified.Comprehensive Health Research Centre (CHRC) - pólo NMSNOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Centro de Estudos de Doenças Crónicas (CEDOC)RUNJácome, CristinaAmaral, RitaAlmeida, RutePereira, Ana MargaridaCouto, MarianaAraújo, LuísAlves-Correia, MagnaPereira, MarianaFerreira-Magalhães, ManuelLoureiro, Cláudia ChavesCatarata, Maria JoanaSantos, Lília MaiaCabral, SaraPereira, JoãoRamos, BárbaraLopes, CristinaMendes, AnaLopes, AnabelaRodrigues, José Carlos CidraisOliveira, GeorgetaAguiar, Ana PaulaAfonso, IveteCarvalho, JoanaArrobas, Ana MariaCosta, JoséValério, MargaridaPereira, MartaAlmeida, TeresaDias, JoanaBom, Ana TodoAzevedo, JoãoRibeiro, CarmelitaAlves, MartaPinto, Paula LeiriaNeuparth, NNeves, Ana CastroPalhinha, AnaMarques, João GasparMartins, PedroTrincão, David PinaBom, Filipa TodoSantos, Maria AlvarengaBranco, JoanaCosta, AlbertoNeto, Armandina SilvaSantalha, MartaLozoya, CarlosSantos, NatachaSilva, DianaVasconcelos, Maria JoãoBarata, Luís TabordaTeixeira, Maria FernandaPinto, DianaAlves, Rodrigo RodriguesMoreira, Ana SofiaPinto, Cláudia SofiaSilva, Pedro MoraisAlves, CarlosCâmara, RaquelCoelho, DidinaBordalo, DianaCarvalho, FernandaFernandes, RicardoFerreira, Rosáriode Oliveira, José FerrazMenezes, FernandoGomes, RicardoCalix, Maria JoséMarques, AnaCardoso, JoãoEmiliano, MadalenaGerardo, RitaNunes, CarlosFerreira, José AlbertoLopes, InêsAlves, AdelaideFonseca, João Almeida2021-03-09T23:58:43Z20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article10application/pdfhttp://hdl.handle.net/10362/113596eng0871-9721PURE: 28528157https://doi.org/10.32932/rpia.2020.12.046info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T04:56:32Zoai:run.unl.pt:10362/113596Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:42:20.435419Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Identification of clusters of asthma control: A preliminary analysis of the inspirers studies |
| title |
Identification of clusters of asthma control: A preliminary analysis of the inspirers studies |
| spellingShingle |
Identification of clusters of asthma control: A preliminary analysis of the inspirers studies Jácome, Cristina Asthma Asthma control Classification Cluster analysis Control of allergic rhinitis and asthma test |
| title_short |
Identification of clusters of asthma control: A preliminary analysis of the inspirers studies |
| title_full |
Identification of clusters of asthma control: A preliminary analysis of the inspirers studies |
| title_fullStr |
Identification of clusters of asthma control: A preliminary analysis of the inspirers studies |
| title_full_unstemmed |
Identification of clusters of asthma control: A preliminary analysis of the inspirers studies |
| title_sort |
Identification of clusters of asthma control: A preliminary analysis of the inspirers studies |
| author |
Jácome, Cristina |
| author_facet |
Jácome, Cristina Amaral, Rita Almeida, Rute Pereira, Ana Margarida Couto, Mariana Araújo, Luís Alves-Correia, Magna Pereira, Mariana Ferreira-Magalhães, Manuel Loureiro, Cláudia Chaves Catarata, Maria Joana Santos, Lília Maia Cabral, Sara Pereira, João Ramos, Bárbara Lopes, Cristina Mendes, Ana Lopes, Anabela Rodrigues, José Carlos Cidrais Oliveira, Georgeta Aguiar, Ana Paula Afonso, Ivete Carvalho, Joana Arrobas, Ana Maria Costa, José Valério, Margarida Pereira, Marta Almeida, Teresa Dias, Joana Bom, Ana Todo Azevedo, João Ribeiro, Carmelita Alves, Marta Pinto, Paula Leiria Neuparth, N Neves, Ana Castro Palhinha, Ana Marques, João Gaspar Martins, Pedro Trincão, David Pina Bom, Filipa Todo Santos, Maria Alvarenga Branco, Joana Costa, Alberto Neto, Armandina Silva Santalha, Marta Lozoya, Carlos Santos, Natacha Silva, Diana Vasconcelos, Maria João Barata, Luís Taborda Teixeira, Maria Fernanda Pinto, Diana Alves, Rodrigo Rodrigues Moreira, Ana Sofia Pinto, Cláudia Sofia Silva, Pedro Morais Alves, Carlos Câmara, Raquel Coelho, Didina Bordalo, Diana Carvalho, Fernanda Fernandes, Ricardo Ferreira, Rosário de Oliveira, José Ferraz Menezes, Fernando Gomes, Ricardo Calix, Maria José Marques, Ana Cardoso, João Emiliano, Madalena Gerardo, Rita Nunes, Carlos Ferreira, José Alberto Lopes, Inês Alves, Adelaide Fonseca, João Almeida |
| author_role |
author |
| author2 |
Amaral, Rita Almeida, Rute Pereira, Ana Margarida Couto, Mariana Araújo, Luís Alves-Correia, Magna Pereira, Mariana Ferreira-Magalhães, Manuel Loureiro, Cláudia Chaves Catarata, Maria Joana Santos, Lília Maia Cabral, Sara Pereira, João Ramos, Bárbara Lopes, Cristina Mendes, Ana Lopes, Anabela Rodrigues, José Carlos Cidrais Oliveira, Georgeta Aguiar, Ana Paula Afonso, Ivete Carvalho, Joana Arrobas, Ana Maria Costa, José Valério, Margarida Pereira, Marta Almeida, Teresa Dias, Joana Bom, Ana Todo Azevedo, João Ribeiro, Carmelita Alves, Marta Pinto, Paula Leiria Neuparth, N Neves, Ana Castro Palhinha, Ana Marques, João Gaspar Martins, Pedro Trincão, David Pina Bom, Filipa Todo Santos, Maria Alvarenga Branco, Joana Costa, Alberto Neto, Armandina Silva Santalha, Marta Lozoya, Carlos Santos, Natacha Silva, Diana Vasconcelos, Maria João Barata, Luís Taborda Teixeira, Maria Fernanda Pinto, Diana Alves, Rodrigo Rodrigues Moreira, Ana Sofia Pinto, Cláudia Sofia Silva, Pedro Morais Alves, Carlos Câmara, Raquel Coelho, Didina Bordalo, Diana Carvalho, Fernanda Fernandes, Ricardo Ferreira, Rosário de Oliveira, José Ferraz Menezes, Fernando Gomes, Ricardo Calix, Maria José Marques, Ana Cardoso, João Emiliano, Madalena Gerardo, Rita Nunes, Carlos Ferreira, José Alberto Lopes, Inês Alves, Adelaide Fonseca, João Almeida |
| author2_role |
author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Comprehensive Health Research Centre (CHRC) - pólo NMS NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) Centro de Estudos de Doenças Crónicas (CEDOC) RUN |
| dc.contributor.author.fl_str_mv |
Jácome, Cristina Amaral, Rita Almeida, Rute Pereira, Ana Margarida Couto, Mariana Araújo, Luís Alves-Correia, Magna Pereira, Mariana Ferreira-Magalhães, Manuel Loureiro, Cláudia Chaves Catarata, Maria Joana Santos, Lília Maia Cabral, Sara Pereira, João Ramos, Bárbara Lopes, Cristina Mendes, Ana Lopes, Anabela Rodrigues, José Carlos Cidrais Oliveira, Georgeta Aguiar, Ana Paula Afonso, Ivete Carvalho, Joana Arrobas, Ana Maria Costa, José Valério, Margarida Pereira, Marta Almeida, Teresa Dias, Joana Bom, Ana Todo Azevedo, João Ribeiro, Carmelita Alves, Marta Pinto, Paula Leiria Neuparth, N Neves, Ana Castro Palhinha, Ana Marques, João Gaspar Martins, Pedro Trincão, David Pina Bom, Filipa Todo Santos, Maria Alvarenga Branco, Joana Costa, Alberto Neto, Armandina Silva Santalha, Marta Lozoya, Carlos Santos, Natacha Silva, Diana Vasconcelos, Maria João Barata, Luís Taborda Teixeira, Maria Fernanda Pinto, Diana Alves, Rodrigo Rodrigues Moreira, Ana Sofia Pinto, Cláudia Sofia Silva, Pedro Morais Alves, Carlos Câmara, Raquel Coelho, Didina Bordalo, Diana Carvalho, Fernanda Fernandes, Ricardo Ferreira, Rosário de Oliveira, José Ferraz Menezes, Fernando Gomes, Ricardo Calix, Maria José Marques, Ana Cardoso, João Emiliano, Madalena Gerardo, Rita Nunes, Carlos Ferreira, José Alberto Lopes, Inês Alves, Adelaide Fonseca, João Almeida |
| dc.subject.por.fl_str_mv |
Asthma Asthma control Classification Cluster analysis Control of allergic rhinitis and asthma test |
| topic |
Asthma Asthma control Classification Cluster analysis Control of allergic rhinitis and asthma test |
| description |
This work was funded by ERDF (European Regional Development Fund) through the operations: POCI- -01-0145-FEDER-029130 (“mINSPIRERS—mHealth to measure and improve adherence to medication in chronic obstructive respiratory diseases - generalisation and evaluation of gamification, peer support and advanced image processing technologies”) co-funded by the COMPETE2020 (Programa Operacional Competitividade e Internacionalização), Portugal 2020 and by Portuguese Funds through FCT (Fundação para a Ciência e a Tecnologia). |
| publishDate |
2020 |
| dc.date.none.fl_str_mv |
2020 2020-01-01T00:00:00Z 2021-03-09T23:58:43Z |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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http://hdl.handle.net/10362/113596 |
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http://hdl.handle.net/10362/113596 |
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eng |
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eng |
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0871-9721 PURE: 28528157 https://doi.org/10.32932/rpia.2020.12.046 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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10 application/pdf |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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