Impact of Beer and Nonalcoholic Beer Consumption on the Gut Microbiota

Detalhes bibliográficos
Autor(a) principal: Marques, Cláudia
Data de Publicação: 2022
Outros Autores: Dinis, Liliana, Barreiros Mota, Inês, Morais, Juliana, Ismael, Shámila, Pereira-Leal, José B, Cardoso, Joana, Ribeiro, Pedro, Beato, Helena, Resende, Mafalda, Espírito Santo, Christophe, Cortez, Ana Paula, Rosário, André, Pestana, Diogo, Teixeira, Diana, Faria, Ana, Calhau, Conceição
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/151194
Resumo: Funding This work was supported by ERDF through the operation POCI-01−0145-ERDF-007746 funded by the Programa Operacional Competitividade e Internacionalização − COMPETE2020 and by FCT - Fundação para a Ciência e a Tecnologia, IP national support through CINTESIS, R&D Unit (UIDB/4255/2020), CHRC (UIDP/04923/2020 and UIDB/04923/2020) and through the project reference PTDC/BAA-AGR/7419/2020.
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spelling Impact of Beer and Nonalcoholic Beer Consumption on the Gut MicrobiotaA Randomized, Double-Blind, Controlled Trialalcoholbeergut microbiotanonalcoholic beerpolyphenolsFunding This work was supported by ERDF through the operation POCI-01−0145-ERDF-007746 funded by the Programa Operacional Competitividade e Internacionalização − COMPETE2020 and by FCT - Fundação para a Ciência e a Tecnologia, IP national support through CINTESIS, R&D Unit (UIDB/4255/2020), CHRC (UIDP/04923/2020 and UIDB/04923/2020) and through the project reference PTDC/BAA-AGR/7419/2020.Gut microbiota modulation might constitute a mechanism mediating the effects of beer on health. In this randomized, double-blinded, two-arm parallel trial, 22 healthy men were recruited to drink 330 mL of nonalcoholic beer (0.0% v/v) or alcoholic beer (5.2% v/v) daily during a 4-week follow-up period. Blood and faecal samples were collected before and after the intervention period. Gut microbiota was analyzed by 16S rRNA gene sequencing. Drinking nonalcoholic or alcoholic beer daily for 4 weeks did not increase body weight and body fat mass and did not changed significantly serum cardiometabolic biomarkers. Nonalcoholic and alcoholic beer increased gut microbiota diversity which has been associated with positive health outcomes and tended to increase faecal alkaline phosphatase activity, a marker of intestinal barrier function. These results suggest the effects of beer on gut microbiota modulation are independent of alcohol and may be mediated by beer polyphenols.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)Comprehensive Health Research Centre (CHRC) - pólo NMSCentro de Estudos de Doenças Crónicas (CEDOC)RUNMarques, CláudiaDinis, LilianaBarreiros Mota, InêsMorais, JulianaIsmael, ShámilaPereira-Leal, José BCardoso, JoanaRibeiro, PedroBeato, HelenaResende, MafaldaEspírito Santo, ChristopheCortez, Ana PaulaRosário, AndréPestana, DiogoTeixeira, DianaFaria, AnaCalhau, Conceição2023-03-24T22:22:39Z2022-10-192022-10-19T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/151194eng0021-8561PURE: 45695915https://doi.org/10.1021/acs.jafc.2c00587info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:33:39Zoai:run.unl.pt:10362/151194Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:54:29.927940Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Impact of Beer and Nonalcoholic Beer Consumption on the Gut Microbiota
A Randomized, Double-Blind, Controlled Trial
title Impact of Beer and Nonalcoholic Beer Consumption on the Gut Microbiota
spellingShingle Impact of Beer and Nonalcoholic Beer Consumption on the Gut Microbiota
Marques, Cláudia
alcohol
beer
gut microbiota
nonalcoholic beer
polyphenols
title_short Impact of Beer and Nonalcoholic Beer Consumption on the Gut Microbiota
title_full Impact of Beer and Nonalcoholic Beer Consumption on the Gut Microbiota
title_fullStr Impact of Beer and Nonalcoholic Beer Consumption on the Gut Microbiota
title_full_unstemmed Impact of Beer and Nonalcoholic Beer Consumption on the Gut Microbiota
title_sort Impact of Beer and Nonalcoholic Beer Consumption on the Gut Microbiota
author Marques, Cláudia
author_facet Marques, Cláudia
Dinis, Liliana
Barreiros Mota, Inês
Morais, Juliana
Ismael, Shámila
Pereira-Leal, José B
Cardoso, Joana
Ribeiro, Pedro
Beato, Helena
Resende, Mafalda
Espírito Santo, Christophe
Cortez, Ana Paula
Rosário, André
Pestana, Diogo
Teixeira, Diana
Faria, Ana
Calhau, Conceição
author_role author
author2 Dinis, Liliana
Barreiros Mota, Inês
Morais, Juliana
Ismael, Shámila
Pereira-Leal, José B
Cardoso, Joana
Ribeiro, Pedro
Beato, Helena
Resende, Mafalda
Espírito Santo, Christophe
Cortez, Ana Paula
Rosário, André
Pestana, Diogo
Teixeira, Diana
Faria, Ana
Calhau, Conceição
author2_role author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)
Comprehensive Health Research Centre (CHRC) - pólo NMS
Centro de Estudos de Doenças Crónicas (CEDOC)
RUN
dc.contributor.author.fl_str_mv Marques, Cláudia
Dinis, Liliana
Barreiros Mota, Inês
Morais, Juliana
Ismael, Shámila
Pereira-Leal, José B
Cardoso, Joana
Ribeiro, Pedro
Beato, Helena
Resende, Mafalda
Espírito Santo, Christophe
Cortez, Ana Paula
Rosário, André
Pestana, Diogo
Teixeira, Diana
Faria, Ana
Calhau, Conceição
dc.subject.por.fl_str_mv alcohol
beer
gut microbiota
nonalcoholic beer
polyphenols
topic alcohol
beer
gut microbiota
nonalcoholic beer
polyphenols
description Funding This work was supported by ERDF through the operation POCI-01−0145-ERDF-007746 funded by the Programa Operacional Competitividade e Internacionalização − COMPETE2020 and by FCT - Fundação para a Ciência e a Tecnologia, IP national support through CINTESIS, R&D Unit (UIDB/4255/2020), CHRC (UIDP/04923/2020 and UIDB/04923/2020) and through the project reference PTDC/BAA-AGR/7419/2020.
publishDate 2022
dc.date.none.fl_str_mv 2022-10-19
2022-10-19T00:00:00Z
2023-03-24T22:22:39Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/151194
url http://hdl.handle.net/10362/151194
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0021-8561
PURE: 45695915
https://doi.org/10.1021/acs.jafc.2c00587
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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