Multiple Myeloma Involvement of the Pancreas: A Case Report of Pancreatic Extramedullary Plasmacytomas Causing Obstructive Jaundice

• Autor(a) principal: Oliveira,Tiago
• Data de Publicação: 2022
• Outros Autores: Mendes,Vasco Ferrão, Antunes,Célia, Oliveira,Carlos, Oliveira,Rui Caetano, Donato,Paulo
• Tipo de documento: Relatório
• Idioma: eng
• Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
• Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S2183-13512022000300020
• topic: Pancreatic extramedullary plasmacytoma; Multiple myeloma; Pancreas; Obstructive jaundice.

Abstract Extramedullary plasmacytomas are rare tumors that can occur either as primary lesions or as a manifestation of multiple myeloma. Pancreatic involvement by plasma cell myeloma is very rare, accounting for less than 0.1% of pancreatic masses. Radiological findings are not specific. The most typical finding of pancreatic plasmacytoma on computed tomography has been reported as the presence of a focal multilobulated mass with homogeneous contrast enhancement. This is a case report of a 74-year-old woman with a previous history of stage III multiple myeloma presented to the emergency department with complaints of abdominal discomfort and painless jaundice. An abdominal ultrasound and computed tomography were performed and revealed a large mass in the topography of the pancreatic head. This mass caused dilatation of the intrahepatic bile ducts and the main bile duct. Subsequently, the patient underwent ultrasound-guided core biopsy of the pancreatic lesion, and the histological analysis of the specimen confirmed the diagnosis of pancreatic plasmacytoma. The purpose of this article is to present a very rare case of pancreatic extramedullary plasmacytomas, describe its epidemiology and clinical features, as well as illustrate its imaging findings.