Evolution of the thyroid hormone-binding protein, transthyretin
Autor(a) principal: | |
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Data de Publicação: | 2000 |
Outros Autores: | , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.1/5454 |
Resumo: | Transthyretin (TTR) belongs to a group of proteins, which includes thyroxine-binding globulin and albumin, that bind to and transport thyroid hormones in the blood. TTR is also indirectly implicated in the carriage of vitamin A through the mediation of retinol-binding protein (RBP). It was first identified in 1942 in human serum and cerebrospinal fluid and was formerly called prealbumin for its ability to migrate faster than serum albumin on electrophoresis of whole plasma. |
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Evolution of the thyroid hormone-binding protein, transthyretinDistribution and functionEvolutionStructureTransthyretinThyroid hormonesTransthyretin (TTR) belongs to a group of proteins, which includes thyroxine-binding globulin and albumin, that bind to and transport thyroid hormones in the blood. TTR is also indirectly implicated in the carriage of vitamin A through the mediation of retinol-binding protein (RBP). It was first identified in 1942 in human serum and cerebrospinal fluid and was formerly called prealbumin for its ability to migrate faster than serum albumin on electrophoresis of whole plasma.ElsevierSapientiaPower, DeborahElias, N. P.Richardson, S. J.Mendes, J.Soares, M. C.Santos, C. R. A.2014-10-24T09:48:37Z20002000-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/5454engD. M. Power, N. P. Elias, S. J. Richardson, J. Mendes, C. M. Soares, and C. R. A. Santos, "Evolution of the Thyroid Hormone-Binding Protein, Transthyretin" in General and Comparative Endocrinology 119, 241–255 (2000)0016-6480AUT: DPO00386;http://dx.doi.org/10.1006/gcen.2000.7520info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:16:38Zoai:sapientia.ualg.pt:10400.1/5454Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:58:28.756180Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Evolution of the thyroid hormone-binding protein, transthyretin |
title |
Evolution of the thyroid hormone-binding protein, transthyretin |
spellingShingle |
Evolution of the thyroid hormone-binding protein, transthyretin Power, Deborah Distribution and function Evolution Structure Transthyretin Thyroid hormones |
title_short |
Evolution of the thyroid hormone-binding protein, transthyretin |
title_full |
Evolution of the thyroid hormone-binding protein, transthyretin |
title_fullStr |
Evolution of the thyroid hormone-binding protein, transthyretin |
title_full_unstemmed |
Evolution of the thyroid hormone-binding protein, transthyretin |
title_sort |
Evolution of the thyroid hormone-binding protein, transthyretin |
author |
Power, Deborah |
author_facet |
Power, Deborah Elias, N. P. Richardson, S. J. Mendes, J. Soares, M. C. Santos, C. R. A. |
author_role |
author |
author2 |
Elias, N. P. Richardson, S. J. Mendes, J. Soares, M. C. Santos, C. R. A. |
author2_role |
author author author author author |
dc.contributor.none.fl_str_mv |
Sapientia |
dc.contributor.author.fl_str_mv |
Power, Deborah Elias, N. P. Richardson, S. J. Mendes, J. Soares, M. C. Santos, C. R. A. |
dc.subject.por.fl_str_mv |
Distribution and function Evolution Structure Transthyretin Thyroid hormones |
topic |
Distribution and function Evolution Structure Transthyretin Thyroid hormones |
description |
Transthyretin (TTR) belongs to a group of proteins, which includes thyroxine-binding globulin and albumin, that bind to and transport thyroid hormones in the blood. TTR is also indirectly implicated in the carriage of vitamin A through the mediation of retinol-binding protein (RBP). It was first identified in 1942 in human serum and cerebrospinal fluid and was formerly called prealbumin for its ability to migrate faster than serum albumin on electrophoresis of whole plasma. |
publishDate |
2000 |
dc.date.none.fl_str_mv |
2000 2000-01-01T00:00:00Z 2014-10-24T09:48:37Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.1/5454 |
url |
http://hdl.handle.net/10400.1/5454 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
D. M. Power, N. P. Elias, S. J. Richardson, J. Mendes, C. M. Soares, and C. R. A. Santos, "Evolution of the Thyroid Hormone-Binding Protein, Transthyretin" in General and Comparative Endocrinology 119, 241–255 (2000) 0016-6480 AUT: DPO00386; http://dx.doi.org/10.1006/gcen.2000.7520 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799133202223202304 |