Cervical cancer in Cape Verde
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10362/149624 |
Resumo: | Funding Information: Publication costs for this article were supported by ecancer (UK Charity number 1176307). Publisher Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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7160 |
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Cervical cancer in Cape Verdereappraisal upon referral to a tertiary cancer centreCape Verdecervical cancerepidemiologyHPV human papillomavirusrisk factorsOncologyCancer ResearchSDG 3 - Good Health and Well-beingFunding Information: Publication costs for this article were supported by ecancer (UK Charity number 1176307). Publisher Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.Background: Cervical cancer (CC) is the first cause of cancer-related deaths among Cape Verdean women. The absence of a national screening programme and a lack of dedicated cancer treatment facilities contribute to its high mortality rate. In an effort to improve the prognosis of these women, a health cooperation agreement was established between Portugal and Cape Verde (CV), allowing their evacuation to Portuguese hospitals. Our aim was to characterise CC among CV women, and to assess the response given to these patients in Instituto Português de Oncologia de Lisboa Francisco Gentil (IPOLFG), so that their treatment and follow-up protocols can be optimised and overall prognosis improved. Methods: Retrospective evaluation of women diagnosed with CC in CV that underwent therapy in IPOLFG between 2013 and 2020. Risk factors, demographic and tumour characteristics, treatment and outcomes were reviewed. Results: Fifty-eight patients were included. Squamous cell carcinoma was the most frequent (91.5%) histological type. HPV DNA was present in 25 out of 26 samples.The agreement rate between the pathology analysis performed in CV and in Portugal was high (87.9%); however, the agreement regarding the FIGO stage was low (15.5%). This may be explained by both the time interval between diagnosis and treatment (around 6 months) and by the absence of resources to accurately stage the disease in CV. In IPOLFG, 77.6% of patients received combined chemo-radiotherapy. Post-treatment follow-up varied widely, due to disease-related and bureaucratic issues. Eighteen patients developed cancer-related complications and/or cancer-related death. The survival rate and median overall survival (OS) in our cohort were of 89.7% and 73.2 months, respectively. Conclusions: Although most women had advanced-stage disease, the OS in our cohort was better than what has been reported for other African countries, probably because state-of-the-art treatment, frequently not accessible in those countries, was offered to all patients.NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM)RUNVilares, Ana TeresaCiabattoni, RiccardoCunha, Teresa MargaridaFélix, Ana2023-02-23T22:21:06Z2022-112022-11-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10362/149624eng1754-6605PURE: 53992025https://doi.org/10.3332/ecancer.2022.1471info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:31:31Zoai:run.unl.pt:10362/149624Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:53:48.674925Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Cervical cancer in Cape Verde reappraisal upon referral to a tertiary cancer centre |
title |
Cervical cancer in Cape Verde |
spellingShingle |
Cervical cancer in Cape Verde Vilares, Ana Teresa Cape Verde cervical cancer epidemiology HPV human papillomavirus risk factors Oncology Cancer Research SDG 3 - Good Health and Well-being |
title_short |
Cervical cancer in Cape Verde |
title_full |
Cervical cancer in Cape Verde |
title_fullStr |
Cervical cancer in Cape Verde |
title_full_unstemmed |
Cervical cancer in Cape Verde |
title_sort |
Cervical cancer in Cape Verde |
author |
Vilares, Ana Teresa |
author_facet |
Vilares, Ana Teresa Ciabattoni, Riccardo Cunha, Teresa Margarida Félix, Ana |
author_role |
author |
author2 |
Ciabattoni, Riccardo Cunha, Teresa Margarida Félix, Ana |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
NOVA Medical School|Faculdade de Ciências Médicas (NMS|FCM) RUN |
dc.contributor.author.fl_str_mv |
Vilares, Ana Teresa Ciabattoni, Riccardo Cunha, Teresa Margarida Félix, Ana |
dc.subject.por.fl_str_mv |
Cape Verde cervical cancer epidemiology HPV human papillomavirus risk factors Oncology Cancer Research SDG 3 - Good Health and Well-being |
topic |
Cape Verde cervical cancer epidemiology HPV human papillomavirus risk factors Oncology Cancer Research SDG 3 - Good Health and Well-being |
description |
Funding Information: Publication costs for this article were supported by ecancer (UK Charity number 1176307). Publisher Copyright: © the authors; licensee ecancermedicalscience. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-11 2022-11-01T00:00:00Z 2023-02-23T22:21:06Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10362/149624 |
url |
http://hdl.handle.net/10362/149624 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1754-6605 PURE: 53992025 https://doi.org/10.3332/ecancer.2022.1471 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
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application/pdf |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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1799138128088268800 |