IGRT com CBCT: o impacto na precisão em radioterapia

Detalhes bibliográficos
Autor(a) principal: Simões, Ana Rita
Data de Publicação: 2012
Tipo de documento: Dissertação
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.21/2317
Resumo: Mestrado em Radiações Aplicadas às Tecnologias da Saúde.
id RCAP_88c6cd790194a3c8cba843a27ffee8c3
oai_identifier_str oai:repositorio.ipl.pt:10400.21/2317
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling IGRT com CBCT: o impacto na precisão em radioterapiaRadioterapiaDesvio de posicionamentoDosimetriaCancro de pescoçoCancro da próstataRadiotherapySet-up deviationCone-beam CTIGRT protocolSetup errorsSistematic errorRandom errorMestrado em Radiações Aplicadas às Tecnologias da Saúde.Precision is an imperative in modern radiotherapy. This concept is applied in a day-to-day basis at all levels in planning and delivering treatment to patients, since only by uniting all these aspects is it’s real application possible. Given that I am a radiation technologist in an institution where the purpose is to ensure accuracy in administered treatment, my main focus was to direct this work towards the field in which I dwell daily. Indeed, making sure that all instruments available have a precisely studied role in the quality of the execution of prescribed treatment has become a necessity that justifies the enormous amount of care put in the treatment phase in radiotherapy. This applies, namely, to the recently-implemented cone-beam computed tomography (CBCT) tool. Therefore, computerized tomography dose indices (CTDI) were acquired in order to monitor doses administered to patients through CBCT. This was followed by the selection of twenty one patients of pathologies involving a great amount of precision: fourteen patients with prostate and seven patients with head and neck tumours. This sample was characterized with the acquisition of CBCT pre and post-treatment, as well as after any correction performed on their positioning. This allowed for evaluating intra-fraction errors. From within this sample, patients out of action limits were chosen, as analyzed in control charts for mean and standard deviation of their positioning deviations, as well as patients out of tolerance limits for deviation correction. Finally, new dosimetric distributions were performed, in which the isocenter accounts for the measured positioning errors. The doses in organs at risk and eventual differences in planning target volume (PTV) coverage with 95% of the dose between these and the planned distributions were compared for each of these patients. This simulation allowed for inferring what would have happened had these errors not been accounted for and corrected. This study also evaluated the feasibility of using CBCT in the imaging verification during the treatment of patients with the aforementioned pathologies, as well as the adequacy of the image acquisition protocol, as currently implemented at the department. The evaluation and quantification of systematic and random translational and rotational errors was also made possible, as defined by current departmental practices. This allowed for adapting not only the mentioned protocol, but also margins currently added to clinical target volumes (CTV) for PTV generation. This will allow to ensure that protocols are based on data obtained locally, which will undoubtedly procure better results in cancer healthcare at the department. It is noteworthy that the Master Comission authorized the presentation of this work as a scientific article, with the purpose of future publication in international, peer-reviewed journals. In order to do so, it is not only written in English, but it also respects criteria related to this objective. In the first part, a review on state-of-the-art literature is rendered (previously submitted in May 2011, even though some aspects have been corrected or updated), as to allow for a contextualization of my work. The feasibility of the IGRT protocol, as implemented at my department, is then assessed. Finally, as previously discussed, systematic and random translational and rotational errors are evaluated.Escola Superior de Tecnologia da Saúde de LisboaEiras, MargaridaGrillo, Isabel MonteiroRCIPLSimões, Ana Rita2013-02-28T15:11:48Z20122012-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/masterThesisapplication/pdfhttp://hdl.handle.net/10400.21/2317porSimões AR. IGRT com CBCT: o impacto na precisão em radioterapia [Dissertation]. Lisboa: Escola Superior de Tecnologia da Saúde de Lisboa/Instituto Politécnico de Lisboa; 2012.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-08-03T09:41:20Zoai:repositorio.ipl.pt:10400.21/2317Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:12:06.333270Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv IGRT com CBCT: o impacto na precisão em radioterapia
title IGRT com CBCT: o impacto na precisão em radioterapia
spellingShingle IGRT com CBCT: o impacto na precisão em radioterapia
Simões, Ana Rita
Radioterapia
Desvio de posicionamento
Dosimetria
Cancro de pescoço
Cancro da próstata
Radiotherapy
Set-up deviation
Cone-beam CT
IGRT protocol
Setup errors
Sistematic error
Random error
title_short IGRT com CBCT: o impacto na precisão em radioterapia
title_full IGRT com CBCT: o impacto na precisão em radioterapia
title_fullStr IGRT com CBCT: o impacto na precisão em radioterapia
title_full_unstemmed IGRT com CBCT: o impacto na precisão em radioterapia
title_sort IGRT com CBCT: o impacto na precisão em radioterapia
author Simões, Ana Rita
author_facet Simões, Ana Rita
author_role author
dc.contributor.none.fl_str_mv Eiras, Margarida
Grillo, Isabel Monteiro
RCIPL
dc.contributor.author.fl_str_mv Simões, Ana Rita
dc.subject.por.fl_str_mv Radioterapia
Desvio de posicionamento
Dosimetria
Cancro de pescoço
Cancro da próstata
Radiotherapy
Set-up deviation
Cone-beam CT
IGRT protocol
Setup errors
Sistematic error
Random error
topic Radioterapia
Desvio de posicionamento
Dosimetria
Cancro de pescoço
Cancro da próstata
Radiotherapy
Set-up deviation
Cone-beam CT
IGRT protocol
Setup errors
Sistematic error
Random error
description Mestrado em Radiações Aplicadas às Tecnologias da Saúde.
publishDate 2012
dc.date.none.fl_str_mv 2012
2012-01-01T00:00:00Z
2013-02-28T15:11:48Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/masterThesis
format masterThesis
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.21/2317
url http://hdl.handle.net/10400.21/2317
dc.language.iso.fl_str_mv por
language por
dc.relation.none.fl_str_mv Simões AR. IGRT com CBCT: o impacto na precisão em radioterapia [Dissertation]. Lisboa: Escola Superior de Tecnologia da Saúde de Lisboa/Instituto Politécnico de Lisboa; 2012.
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Escola Superior de Tecnologia da Saúde de Lisboa
publisher.none.fl_str_mv Escola Superior de Tecnologia da Saúde de Lisboa
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799133375710101504

Registros relacionados