Risk Calculators in Bipolar Disorder: A Systematic Review
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/105841 https://doi.org/10.3390/brainsci10080525 |
Resumo: | Introduction: Early recognition of bipolar disorder improves the prognosis and decreases the burden of the disease. However, there is a significant delay in diagnosis. Multiple risk factors for bipolar disorder have been identified and a population at high-risk for the disorder has been more precisely defined. These advances have allowed the development of risk calculators to predict individual risk of conversion to bipolar disorder. This review aims to identify the risk calculators for bipolar disorder and assess their clinical applicability. Methods: A systematic review of original studies on the development of risk calculators in bipolar disorder was performed. The studies’ quality was evaluated with the Newcastle-Ottawa Quality Assessment Form for Cohort Studies and according to recommendations of the Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis Initiative. Results: Three studies met the inclusion criteria; one developed a risk calculator of conversion from major depressive episode to bipolar disorder; one of conversion to new-onset bipolar spectrum disorders in o spring of parents with bipolar disorder; and the last one of conversion in youths with bipolar disorder not-otherwise-specified. Conclusions: The calculators reviewed in this article present good discrimination power for bipolar disorder, although future replication and validation of the models is needed. |
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7160 |
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Risk Calculators in Bipolar Disorder: A Systematic Reviewbipolar disorderbipolar depressionrisk predictionrisk calculatorrisk scoreIntroduction: Early recognition of bipolar disorder improves the prognosis and decreases the burden of the disease. However, there is a significant delay in diagnosis. Multiple risk factors for bipolar disorder have been identified and a population at high-risk for the disorder has been more precisely defined. These advances have allowed the development of risk calculators to predict individual risk of conversion to bipolar disorder. This review aims to identify the risk calculators for bipolar disorder and assess their clinical applicability. Methods: A systematic review of original studies on the development of risk calculators in bipolar disorder was performed. The studies’ quality was evaluated with the Newcastle-Ottawa Quality Assessment Form for Cohort Studies and according to recommendations of the Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis Initiative. Results: Three studies met the inclusion criteria; one developed a risk calculator of conversion from major depressive episode to bipolar disorder; one of conversion to new-onset bipolar spectrum disorders in o spring of parents with bipolar disorder; and the last one of conversion in youths with bipolar disorder not-otherwise-specified. Conclusions: The calculators reviewed in this article present good discrimination power for bipolar disorder, although future replication and validation of the models is needed.MDPI2020-08-06info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/105841http://hdl.handle.net/10316/105841https://doi.org/10.3390/brainsci10080525eng2076-3425Ribeiro, Joana SilvaPereira, DanielaSalagre, EstelaCoroa, ManuelSantos Oliveira, PedroSantos, VítorMadeira, NunoGrande, IriaVieta, Eduardinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-03-10T21:34:17Zoai:estudogeral.uc.pt:10316/105841Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:22:20.410763Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Risk Calculators in Bipolar Disorder: A Systematic Review |
title |
Risk Calculators in Bipolar Disorder: A Systematic Review |
spellingShingle |
Risk Calculators in Bipolar Disorder: A Systematic Review Ribeiro, Joana Silva bipolar disorder bipolar depression risk prediction risk calculator risk score |
title_short |
Risk Calculators in Bipolar Disorder: A Systematic Review |
title_full |
Risk Calculators in Bipolar Disorder: A Systematic Review |
title_fullStr |
Risk Calculators in Bipolar Disorder: A Systematic Review |
title_full_unstemmed |
Risk Calculators in Bipolar Disorder: A Systematic Review |
title_sort |
Risk Calculators in Bipolar Disorder: A Systematic Review |
author |
Ribeiro, Joana Silva |
author_facet |
Ribeiro, Joana Silva Pereira, Daniela Salagre, Estela Coroa, Manuel Santos Oliveira, Pedro Santos, Vítor Madeira, Nuno Grande, Iria Vieta, Eduard |
author_role |
author |
author2 |
Pereira, Daniela Salagre, Estela Coroa, Manuel Santos Oliveira, Pedro Santos, Vítor Madeira, Nuno Grande, Iria Vieta, Eduard |
author2_role |
author author author author author author author author |
dc.contributor.author.fl_str_mv |
Ribeiro, Joana Silva Pereira, Daniela Salagre, Estela Coroa, Manuel Santos Oliveira, Pedro Santos, Vítor Madeira, Nuno Grande, Iria Vieta, Eduard |
dc.subject.por.fl_str_mv |
bipolar disorder bipolar depression risk prediction risk calculator risk score |
topic |
bipolar disorder bipolar depression risk prediction risk calculator risk score |
description |
Introduction: Early recognition of bipolar disorder improves the prognosis and decreases the burden of the disease. However, there is a significant delay in diagnosis. Multiple risk factors for bipolar disorder have been identified and a population at high-risk for the disorder has been more precisely defined. These advances have allowed the development of risk calculators to predict individual risk of conversion to bipolar disorder. This review aims to identify the risk calculators for bipolar disorder and assess their clinical applicability. Methods: A systematic review of original studies on the development of risk calculators in bipolar disorder was performed. The studies’ quality was evaluated with the Newcastle-Ottawa Quality Assessment Form for Cohort Studies and according to recommendations of the Transparent Reporting of a multivariable prediction model for Individual Prognosis or Diagnosis Initiative. Results: Three studies met the inclusion criteria; one developed a risk calculator of conversion from major depressive episode to bipolar disorder; one of conversion to new-onset bipolar spectrum disorders in o spring of parents with bipolar disorder; and the last one of conversion in youths with bipolar disorder not-otherwise-specified. Conclusions: The calculators reviewed in this article present good discrimination power for bipolar disorder, although future replication and validation of the models is needed. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-08-06 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/105841 http://hdl.handle.net/10316/105841 https://doi.org/10.3390/brainsci10080525 |
url |
http://hdl.handle.net/10316/105841 https://doi.org/10.3390/brainsci10080525 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2076-3425 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
MDPI |
publisher.none.fl_str_mv |
MDPI |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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