ISCHAEMIA IN THE NEONATE–CASE REPORT

Detalhes bibliográficos
Autor(a) principal: Rodrigues, Roger
Data de Publicação: 2018
Outros Autores: Anacleto, Gabriel, Mendes, Carolina, Varino, Juliana, Marinho, André, Pereira, Bárbara, Moreira, Mário, Correia, Mafalda, Lima, Pedro, Gonçalves, Óscar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.48750/acv.64
Resumo: Introduction: Peripheral ischaemia and gangrene in a neonate is rare,with fewer than a hundred cases reported in the literature. Neonatal limb ischaemia present considerable challenges in diagnosis and management. The published literature is limited to case reports and case series and there are no large trials comparing different therapies. Objectives: The authors describe the case of a 4-day newborn transferred to the Pediatric Hospital for a gangrene of the lower limb. Results: In this case the member was not salvageable. Treatment with Heparin was performed which is usually effective in cases of neonatal limb ischaemia, but in this case the evolution was not favorable. The diagnosis was late and an amputation of the leg was performed. A multidisciplinary team of surgeons, paediatricians, occupational therapists, physiotherapists, working together provided the best support network and best treatment for this child. Conclusions: Neonatal limb ischaemia is uncommon, but can have devastating consequences on the patient. Successful management is dependent on early recognition, rapid clinical assessment and appropriate therapy. Initial supportive therapy may be appropriate with aggressive interventional treatment reserved for selective cases. Interventional treatment includes thrombolysis using a tissue plasminogen activator which can be catheter directed or systemic, and surgical thrombectomy, particularly if larger vessels such as the abdominal aorta are involved. Strategies for management are still evolving, and there is only a limited pooled experience available for review in the published literature.
id RCAP_8997516a6c37b5615d8ca6df0d14ac9b
oai_identifier_str oai:ojs.acvjournal.com:article/64
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling ISCHAEMIA IN THE NEONATE–CASE REPORTISQUÉMIA NO RECÉM-NASCIDO — RELATO DE UM CASOGangreneLower ExtremityNeonateGangrenaRecém-nascidotrombose arterialIntroduction: Peripheral ischaemia and gangrene in a neonate is rare,with fewer than a hundred cases reported in the literature. Neonatal limb ischaemia present considerable challenges in diagnosis and management. The published literature is limited to case reports and case series and there are no large trials comparing different therapies. Objectives: The authors describe the case of a 4-day newborn transferred to the Pediatric Hospital for a gangrene of the lower limb. Results: In this case the member was not salvageable. Treatment with Heparin was performed which is usually effective in cases of neonatal limb ischaemia, but in this case the evolution was not favorable. The diagnosis was late and an amputation of the leg was performed. A multidisciplinary team of surgeons, paediatricians, occupational therapists, physiotherapists, working together provided the best support network and best treatment for this child. Conclusions: Neonatal limb ischaemia is uncommon, but can have devastating consequences on the patient. Successful management is dependent on early recognition, rapid clinical assessment and appropriate therapy. Initial supportive therapy may be appropriate with aggressive interventional treatment reserved for selective cases. Interventional treatment includes thrombolysis using a tissue plasminogen activator which can be catheter directed or systemic, and surgical thrombectomy, particularly if larger vessels such as the abdominal aorta are involved. Strategies for management are still evolving, and there is only a limited pooled experience available for review in the published literature.A Isquémia aguda de um membro e gangrena no recém-nascido são uma condição rara e desafiadora. Em crianças, o comprometimento vascular que afeta os membros no período pós-natal pode ser resultante de distúrbios da coagulação, sépsis, diabetes gestacional ou lesões iatrogênicas. A abordagem clínica desses pacientes pode variar desde, terapia conservadora até a opções mais invasivas como trombólise e a tromboembolectomia cirúrgica em uma população selecionada. Descrevemos o caso de um recém-nascido com uma gangrena do membro inferior.Sociedade Portuguesa de Angiologia e Cirurgia Vascular2018-06-07T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.48750/acv.64oai:ojs.acvjournal.com:article/64Angiologia e Cirurgia Vascular; Vol. 14 No. 2 (2018): June; 141-143Angiologia e Cirurgia Vascular; Vol. 14 N.º 2 (2018): Junho; 141-1432183-00961646-706Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://acvjournal.com/index.php/acv/article/view/64https://doi.org/10.48750/acv.64http://acvjournal.com/index.php/acv/article/view/64/97Copyright (c) 2018 Angiologia e Cirurgia Vascularinfo:eu-repo/semantics/openAccessRodrigues, RogerAnacleto, GabrielMendes, CarolinaVarino, JulianaMarinho, AndréPereira, BárbaraMoreira, MárioCorreia, MafaldaLima, PedroGonçalves, Óscar2022-05-23T15:10:00Zoai:ojs.acvjournal.com:article/64Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T14:57:28.742401Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv ISCHAEMIA IN THE NEONATE–CASE REPORT
ISQUÉMIA NO RECÉM-NASCIDO — RELATO DE UM CASO
title ISCHAEMIA IN THE NEONATE–CASE REPORT
spellingShingle ISCHAEMIA IN THE NEONATE–CASE REPORT
Rodrigues, Roger
Gangrene
Lower Extremity
Neonate
Gangrena
Recém-nascido
trombose arterial
title_short ISCHAEMIA IN THE NEONATE–CASE REPORT
title_full ISCHAEMIA IN THE NEONATE–CASE REPORT
title_fullStr ISCHAEMIA IN THE NEONATE–CASE REPORT
title_full_unstemmed ISCHAEMIA IN THE NEONATE–CASE REPORT
title_sort ISCHAEMIA IN THE NEONATE–CASE REPORT
author Rodrigues, Roger
author_facet Rodrigues, Roger
Anacleto, Gabriel
Mendes, Carolina
Varino, Juliana
Marinho, André
Pereira, Bárbara
Moreira, Mário
Correia, Mafalda
Lima, Pedro
Gonçalves, Óscar
author_role author
author2 Anacleto, Gabriel
Mendes, Carolina
Varino, Juliana
Marinho, André
Pereira, Bárbara
Moreira, Mário
Correia, Mafalda
Lima, Pedro
Gonçalves, Óscar
author2_role author
author
author
author
author
author
author
author
author
dc.contributor.author.fl_str_mv Rodrigues, Roger
Anacleto, Gabriel
Mendes, Carolina
Varino, Juliana
Marinho, André
Pereira, Bárbara
Moreira, Mário
Correia, Mafalda
Lima, Pedro
Gonçalves, Óscar
dc.subject.por.fl_str_mv Gangrene
Lower Extremity
Neonate
Gangrena
Recém-nascido
trombose arterial
topic Gangrene
Lower Extremity
Neonate
Gangrena
Recém-nascido
trombose arterial
description Introduction: Peripheral ischaemia and gangrene in a neonate is rare,with fewer than a hundred cases reported in the literature. Neonatal limb ischaemia present considerable challenges in diagnosis and management. The published literature is limited to case reports and case series and there are no large trials comparing different therapies. Objectives: The authors describe the case of a 4-day newborn transferred to the Pediatric Hospital for a gangrene of the lower limb. Results: In this case the member was not salvageable. Treatment with Heparin was performed which is usually effective in cases of neonatal limb ischaemia, but in this case the evolution was not favorable. The diagnosis was late and an amputation of the leg was performed. A multidisciplinary team of surgeons, paediatricians, occupational therapists, physiotherapists, working together provided the best support network and best treatment for this child. Conclusions: Neonatal limb ischaemia is uncommon, but can have devastating consequences on the patient. Successful management is dependent on early recognition, rapid clinical assessment and appropriate therapy. Initial supportive therapy may be appropriate with aggressive interventional treatment reserved for selective cases. Interventional treatment includes thrombolysis using a tissue plasminogen activator which can be catheter directed or systemic, and surgical thrombectomy, particularly if larger vessels such as the abdominal aorta are involved. Strategies for management are still evolving, and there is only a limited pooled experience available for review in the published literature.
publishDate 2018
dc.date.none.fl_str_mv 2018-06-07T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.48750/acv.64
oai:ojs.acvjournal.com:article/64
url https://doi.org/10.48750/acv.64
identifier_str_mv oai:ojs.acvjournal.com:article/64
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv http://acvjournal.com/index.php/acv/article/view/64
https://doi.org/10.48750/acv.64
http://acvjournal.com/index.php/acv/article/view/64/97
dc.rights.driver.fl_str_mv Copyright (c) 2018 Angiologia e Cirurgia Vascular
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2018 Angiologia e Cirurgia Vascular
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
publisher.none.fl_str_mv Sociedade Portuguesa de Angiologia e Cirurgia Vascular
dc.source.none.fl_str_mv Angiologia e Cirurgia Vascular; Vol. 14 No. 2 (2018): June; 141-143
Angiologia e Cirurgia Vascular; Vol. 14 N.º 2 (2018): Junho; 141-143
2183-0096
1646-706X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799129848669536256