Nasal mucocutaneous leishmaniasis – An unusual form of presentation
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2023 |
| Outros Autores: | , , , , , |
| Tipo de documento: | Artigo |
| Idioma: | eng por |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| DOI: | 10.34631/sporl.1084 |
| Texto Completo: | https://doi.org/10.34631/sporl.1084 |
Resumo: | Leishmaniasis is caused by the protozoan parasite Leishmania which is transmitted through bites of infected female phlebotomine sandflies. There are 3 main forms – visceral, cutaneous and mucocutaneous, with mucosal affection being the rarest manifestation of the disease. The incidence in Portugal is considered hypoendemic. We present a case of a 48 years old female, with complaints of nasal obstruction, epistaxis and irregular erythematous scaly plaques surrounding the nostrils. Histology of the nasal septum and skin revealed the presence of Leishmania-Donovan bodies. She was treated with amphotericin-B and itraconazole with clinical improvement and disappearance of lesions. Mucocutaneous leishmaniasis preferably affects the nasal mucosa and if not diagnosed and treated in time can lead to cartilage destruction and dissemination of mucosal lesions to the nasopharynx, larynx, compromising the airway and even leading to disfigurement. |
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Nasal mucocutaneous leishmaniasis – An unusual form of presentationLeishmaniose mucocutânea nasal – Uma manifestação rara da doençaleishmanioseleishmaniose mucocutânealeishmaniose nasalleishmaniasismucocutaneous leishmaniasisnasal leishmaniasisLeishmaniasis is caused by the protozoan parasite Leishmania which is transmitted through bites of infected female phlebotomine sandflies. There are 3 main forms – visceral, cutaneous and mucocutaneous, with mucosal affection being the rarest manifestation of the disease. The incidence in Portugal is considered hypoendemic. We present a case of a 48 years old female, with complaints of nasal obstruction, epistaxis and irregular erythematous scaly plaques surrounding the nostrils. Histology of the nasal septum and skin revealed the presence of Leishmania-Donovan bodies. She was treated with amphotericin-B and itraconazole with clinical improvement and disappearance of lesions. Mucocutaneous leishmaniasis preferably affects the nasal mucosa and if not diagnosed and treated in time can lead to cartilage destruction and dissemination of mucosal lesions to the nasopharynx, larynx, compromising the airway and even leading to disfigurement.A leishmaniose é uma doença infeciosa, causada por protozoários do género Leishmania, cujo vetor de transmissão é a picada de mosquitos (fêmeas) chamados flebótomos. Existem três formas principais – visceral, cutânea e mucocutânea, sendo a afeção da mucosa a manifestação mais rara da doença. A incidência em Portugal é considerada hipoendémica. Apresentamos um caso clínico de uma mulher, com queixas de obstrução nasal, epistáxis e lesões irregulares eritematosas a nível das asas do nariz, columela, vestíbulo e septo nasal. Foram realizadas biópsias das lesões cutâneas e da mucosa nasal que revelaram a presença de corpos de Leishman-Donovan. A doente foi submetida a tratamento com anfotericina B e itraconazol com boa evolução clínica e desaparecimento das lesões. A leishmaniose mucocutânea atinge preferencialmente a mucosa nasal e se não diagnosticada e tratada atempadamente pode levar a destruição da cartilagem e disseminação das lesões para a nasofaringe, faringe e laringe comprometendo a via aérea e provocando desfiguração.Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço2023-03-16info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/pdfhttps://doi.org/10.34631/sporl.1084https://doi.org/10.34631/sporl.1084Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 61 No. 1 (2023): March; 101-105Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 61 Núm. 1 (2023): Março; 101-105Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 61 N.º 1 (2023): Março; 101-1052184-6499reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPengporhttps://journalsporl.com/index.php/sporl/article/view/2015https://journalsporl.com/index.php/sporl/article/view/2015/23https://journalsporl.com/index.php/sporl/article/view/2015/24Direitos de Autor (c) 2023 Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoçoinfo:eu-repo/semantics/openAccessEloi, IsaSilva, Nuno DiasCarneiro, José PedroCarvalho, Filipa VazRibeiro, João CarlosMiguéis, António CarlosMiguéis, Jorge Eva2024-06-06T12:56:59Zoai:journalsporl.com:article/2015Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-06-06T12:56:59Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Nasal mucocutaneous leishmaniasis – An unusual form of presentation Leishmaniose mucocutânea nasal – Uma manifestação rara da doença |
| title |
Nasal mucocutaneous leishmaniasis – An unusual form of presentation |
| spellingShingle |
Nasal mucocutaneous leishmaniasis – An unusual form of presentation Nasal mucocutaneous leishmaniasis – An unusual form of presentation Eloi, Isa leishmaniose leishmaniose mucocutânea leishmaniose nasal leishmaniasis mucocutaneous leishmaniasis nasal leishmaniasis Eloi, Isa leishmaniose leishmaniose mucocutânea leishmaniose nasal leishmaniasis mucocutaneous leishmaniasis nasal leishmaniasis |
| title_short |
Nasal mucocutaneous leishmaniasis – An unusual form of presentation |
| title_full |
Nasal mucocutaneous leishmaniasis – An unusual form of presentation |
| title_fullStr |
Nasal mucocutaneous leishmaniasis – An unusual form of presentation Nasal mucocutaneous leishmaniasis – An unusual form of presentation |
| title_full_unstemmed |
Nasal mucocutaneous leishmaniasis – An unusual form of presentation Nasal mucocutaneous leishmaniasis – An unusual form of presentation |
| title_sort |
Nasal mucocutaneous leishmaniasis – An unusual form of presentation |
| author |
Eloi, Isa |
| author_facet |
Eloi, Isa Eloi, Isa Silva, Nuno Dias Carneiro, José Pedro Carvalho, Filipa Vaz Ribeiro, João Carlos Miguéis, António Carlos Miguéis, Jorge Eva Silva, Nuno Dias Carneiro, José Pedro Carvalho, Filipa Vaz Ribeiro, João Carlos Miguéis, António Carlos Miguéis, Jorge Eva |
| author_role |
author |
| author2 |
Silva, Nuno Dias Carneiro, José Pedro Carvalho, Filipa Vaz Ribeiro, João Carlos Miguéis, António Carlos Miguéis, Jorge Eva |
| author2_role |
author author author author author author |
| dc.contributor.author.fl_str_mv |
Eloi, Isa Silva, Nuno Dias Carneiro, José Pedro Carvalho, Filipa Vaz Ribeiro, João Carlos Miguéis, António Carlos Miguéis, Jorge Eva |
| dc.subject.por.fl_str_mv |
leishmaniose leishmaniose mucocutânea leishmaniose nasal leishmaniasis mucocutaneous leishmaniasis nasal leishmaniasis |
| topic |
leishmaniose leishmaniose mucocutânea leishmaniose nasal leishmaniasis mucocutaneous leishmaniasis nasal leishmaniasis |
| description |
Leishmaniasis is caused by the protozoan parasite Leishmania which is transmitted through bites of infected female phlebotomine sandflies. There are 3 main forms – visceral, cutaneous and mucocutaneous, with mucosal affection being the rarest manifestation of the disease. The incidence in Portugal is considered hypoendemic. We present a case of a 48 years old female, with complaints of nasal obstruction, epistaxis and irregular erythematous scaly plaques surrounding the nostrils. Histology of the nasal septum and skin revealed the presence of Leishmania-Donovan bodies. She was treated with amphotericin-B and itraconazole with clinical improvement and disappearance of lesions. Mucocutaneous leishmaniasis preferably affects the nasal mucosa and if not diagnosed and treated in time can lead to cartilage destruction and dissemination of mucosal lesions to the nasopharynx, larynx, compromising the airway and even leading to disfigurement. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-03-16 |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
| format |
article |
| status_str |
publishedVersion |
| dc.identifier.uri.fl_str_mv |
https://doi.org/10.34631/sporl.1084 https://doi.org/10.34631/sporl.1084 |
| url |
https://doi.org/10.34631/sporl.1084 |
| dc.language.iso.fl_str_mv |
eng por |
| language |
eng por |
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https://journalsporl.com/index.php/sporl/article/view/2015 https://journalsporl.com/index.php/sporl/article/view/2015/23 https://journalsporl.com/index.php/sporl/article/view/2015/24 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf application/pdf |
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Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço |
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Sociedade Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço |
| dc.source.none.fl_str_mv |
Portuguese Journal of Otorhinolaryngology and Head and Neck Surgery; Vol. 61 No. 1 (2023): March; 101-105 Revista Portuguesa de Otorrinolaringologia e Cirurgia de Cabeça e Pescoço; Vol. 61 Núm. 1 (2023): Março; 101-105 Revista Portuguesa de Otorrinolaringologia-Cirurgia de Cabeça e Pescoço; Vol. 61 N.º 1 (2023): Março; 101-105 2184-6499 reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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10.34631/sporl.1084 |