Electrochemistry combined-surface plasmon resonance biosensors: A review
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/1822/79872 |
Resumo: | Over the years, most of the literature reported applications of electrochemical and surface plasmon resonance (SPR) immunoassays for biosensing but, so far, the combination of the two methods in the same sensing spot for analytical purposes is much less explored and discussed. The aim of this Review is to highlight the great potential of electrochemistry combined-SPR (eSPR) as analytical tool for screening chemically and biologically relevant (bio)molecules by combining the unique features of SPR integrated with electrochemical readout. In the first part of the Review, we describe the urgent need of innovative methods for screening clinical biological markers (General Introduction), briefly discuss general concepts of SPR and electrochemical sensing (Concepts behind eSPR biosensors) and highlight the hyphenation of two methods to developed combined biosensing systems (Set-up configuration and eSPR principles). Firstly, we briefly give an overview of the setup for implementation of eSPR technique and discuss some relevant experimental conditions to perform the combined optical and electrochemical measurements. Then, the principles and fundamentals of eSPR biosensors are presented and described. We also present representative examples of eSPR biosensors in the literature (Applications of eSPR biosensors). In the second part, we review studies on how combined electrical and plasmonic detection contributed to the biosensing field, in particular, for the successful screening of clinically relevant biomolecules, namely proteins (Detection of proteins), nucleic acids (Detection of nucleic acids), small size chemical species (Detection of small molecules) and cells (Living-cell Analysis). Finally, we discuss the current limitations of eSPR biosensors performance and suggest possible ways to overcome these limitations (Limitations and optimization) and then we explore aspects about the development of the method and its applications and discuss areas of likely future growth (Conclusions and perspectives). |
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Electrochemistry combined-surface plasmon resonance biosensors: A reviewElectrochemistrySPRElectrochemistry combined-surface plasmon resonance (eSPR)DetectionNucleic acidsProteinBiomarkersElectrochemistry combined -surfaceplasmon resonance (eSPR)Science & TechnologyOver the years, most of the literature reported applications of electrochemical and surface plasmon resonance (SPR) immunoassays for biosensing but, so far, the combination of the two methods in the same sensing spot for analytical purposes is much less explored and discussed. The aim of this Review is to highlight the great potential of electrochemistry combined-SPR (eSPR) as analytical tool for screening chemically and biologically relevant (bio)molecules by combining the unique features of SPR integrated with electrochemical readout. In the first part of the Review, we describe the urgent need of innovative methods for screening clinical biological markers (General Introduction), briefly discuss general concepts of SPR and electrochemical sensing (Concepts behind eSPR biosensors) and highlight the hyphenation of two methods to developed combined biosensing systems (Set-up configuration and eSPR principles). Firstly, we briefly give an overview of the setup for implementation of eSPR technique and discuss some relevant experimental conditions to perform the combined optical and electrochemical measurements. Then, the principles and fundamentals of eSPR biosensors are presented and described. We also present representative examples of eSPR biosensors in the literature (Applications of eSPR biosensors). In the second part, we review studies on how combined electrical and plasmonic detection contributed to the biosensing field, in particular, for the successful screening of clinically relevant biomolecules, namely proteins (Detection of proteins), nucleic acids (Detection of nucleic acids), small size chemical species (Detection of small molecules) and cells (Living-cell Analysis). Finally, we discuss the current limitations of eSPR biosensors performance and suggest possible ways to overcome these limitations (Limitations and optimization) and then we explore aspects about the development of the method and its applications and discuss areas of likely future growth (Conclusions and perspectives).This research had the financial support of FCT (Fundação para a Ciência e Tecnologia) and co-financed by the European Union (FEDER funds) under the Partnership Agreement PT2020, Research Grant Pest-C/QUI/UIDB/00081/2020 (CIQUP). J.A. Ribeiro (ref. SFRH/BPD/105395/2014) and C.M. Pereira (ref. SFRH/BSAB/150320/2019) acknowledge FCT under the QREN – POPH – Advanced Training, subsidized by European Union and national MEC funds. The authors acknowledge the research project MyTag (ref. PTDC/EEI-EEE/4832/2021), funded by FCT, for financial support.info:eu-repo/semantics/publishedVersionElsevierUniversidade do MinhoRibeiro, JoséSales, M. G. F.Pereira, Carlos M.2022-122022-12-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/79872engRibeiro, José; Sales, M. G. F.; Pereira, Carlos M., Electrochemistry combined-surface plasmon resonance biosensors: A review. TrAC-Trends in Analytical Chemistry, 157(116766), 20220165-993610.1016/j.trac.2022.116766116766https://www.sciencedirect.com/science/article/pii/S0165993622002497info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:39:22Zoai:repositorium.sdum.uminho.pt:1822/79872Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:35:58.424471Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Electrochemistry combined-surface plasmon resonance biosensors: A review |
title |
Electrochemistry combined-surface plasmon resonance biosensors: A review |
spellingShingle |
Electrochemistry combined-surface plasmon resonance biosensors: A review Ribeiro, José Electrochemistry SPR Electrochemistry combined-surface plasmon resonance (eSPR) Detection Nucleic acids Protein Biomarkers Electrochemistry combined -surface plasmon resonance (eSPR) Science & Technology |
title_short |
Electrochemistry combined-surface plasmon resonance biosensors: A review |
title_full |
Electrochemistry combined-surface plasmon resonance biosensors: A review |
title_fullStr |
Electrochemistry combined-surface plasmon resonance biosensors: A review |
title_full_unstemmed |
Electrochemistry combined-surface plasmon resonance biosensors: A review |
title_sort |
Electrochemistry combined-surface plasmon resonance biosensors: A review |
author |
Ribeiro, José |
author_facet |
Ribeiro, José Sales, M. G. F. Pereira, Carlos M. |
author_role |
author |
author2 |
Sales, M. G. F. Pereira, Carlos M. |
author2_role |
author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Ribeiro, José Sales, M. G. F. Pereira, Carlos M. |
dc.subject.por.fl_str_mv |
Electrochemistry SPR Electrochemistry combined-surface plasmon resonance (eSPR) Detection Nucleic acids Protein Biomarkers Electrochemistry combined -surface plasmon resonance (eSPR) Science & Technology |
topic |
Electrochemistry SPR Electrochemistry combined-surface plasmon resonance (eSPR) Detection Nucleic acids Protein Biomarkers Electrochemistry combined -surface plasmon resonance (eSPR) Science & Technology |
description |
Over the years, most of the literature reported applications of electrochemical and surface plasmon resonance (SPR) immunoassays for biosensing but, so far, the combination of the two methods in the same sensing spot for analytical purposes is much less explored and discussed. The aim of this Review is to highlight the great potential of electrochemistry combined-SPR (eSPR) as analytical tool for screening chemically and biologically relevant (bio)molecules by combining the unique features of SPR integrated with electrochemical readout. In the first part of the Review, we describe the urgent need of innovative methods for screening clinical biological markers (General Introduction), briefly discuss general concepts of SPR and electrochemical sensing (Concepts behind eSPR biosensors) and highlight the hyphenation of two methods to developed combined biosensing systems (Set-up configuration and eSPR principles). Firstly, we briefly give an overview of the setup for implementation of eSPR technique and discuss some relevant experimental conditions to perform the combined optical and electrochemical measurements. Then, the principles and fundamentals of eSPR biosensors are presented and described. We also present representative examples of eSPR biosensors in the literature (Applications of eSPR biosensors). In the second part, we review studies on how combined electrical and plasmonic detection contributed to the biosensing field, in particular, for the successful screening of clinically relevant biomolecules, namely proteins (Detection of proteins), nucleic acids (Detection of nucleic acids), small size chemical species (Detection of small molecules) and cells (Living-cell Analysis). Finally, we discuss the current limitations of eSPR biosensors performance and suggest possible ways to overcome these limitations (Limitations and optimization) and then we explore aspects about the development of the method and its applications and discuss areas of likely future growth (Conclusions and perspectives). |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-12 2022-12-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/1822/79872 |
url |
https://hdl.handle.net/1822/79872 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Ribeiro, José; Sales, M. G. F.; Pereira, Carlos M., Electrochemistry combined-surface plasmon resonance biosensors: A review. TrAC-Trends in Analytical Chemistry, 157(116766), 2022 0165-9936 10.1016/j.trac.2022.116766 116766 https://www.sciencedirect.com/science/article/pii/S0165993622002497 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Elsevier |
publisher.none.fl_str_mv |
Elsevier |
dc.source.none.fl_str_mv |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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