Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study
Autor(a) principal: | |
---|---|
Data de Publicação: | 2021 |
Outros Autores: | , , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.1/15041 |
Resumo: | Background We intended to estimate the proportion hypoglycemic/hyperglycemic emergency episodes in treated diabetes mellitus (DM) patients admitted to a hospital ward, and calculate the prevalence of risk factors for hypoglycemia and diabetic complications. Methods In this cross-sectional, multicentered study, the observational data was collected by physicians from patient’s hospitalization to discharge/death. Statistical tests were 2-tailed considering 5% significance level. Results There were 646 ward admissions due to hyperglycemic emergencies and 176 hypoglycemic episodes with a ratio hypoglycemia/hyperglycemia 0.27 for all DM patients. In T2DM patients the ratio was 0.38. These were mainly female (55.1%), functionally dependent (61.4%) and retired/disabled (73.1%). Median age was 75 years and median duration of disease 11 years. Half the patients were on insulin-based therapy and 30.1% on secretagogue-based therapy. Approximately 57% of patients needed occasional/full assistance to manage the disease. The most frequent risk factor for hypoglycemia was polypharmacy (85.0%). Hypoglycemia in the 12 months before admission was higher in insulin-based therapy patients (66.1%; p = 0.001). Conclusions Hyperglycemic emergencies are the most frequent cause of hospitalization in Portugal, although severe hypoglycemic events represent a health and social problem in elderly/frail patients. There is still the need to optimize therapy in terms of the potential for hypoglycemia in this patient group and a review of anti-hyperglycemic agents to add on to insulin. |
id |
RCAP_8aa199818649db1f4f9dca8f8e8b8546 |
---|---|
oai_identifier_str |
oai:sapientia.ualg.pt:10400.1/15041 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD studyDiabetesHypoglycemic episodesInpatientsBackground We intended to estimate the proportion hypoglycemic/hyperglycemic emergency episodes in treated diabetes mellitus (DM) patients admitted to a hospital ward, and calculate the prevalence of risk factors for hypoglycemia and diabetic complications. Methods In this cross-sectional, multicentered study, the observational data was collected by physicians from patient’s hospitalization to discharge/death. Statistical tests were 2-tailed considering 5% significance level. Results There were 646 ward admissions due to hyperglycemic emergencies and 176 hypoglycemic episodes with a ratio hypoglycemia/hyperglycemia 0.27 for all DM patients. In T2DM patients the ratio was 0.38. These were mainly female (55.1%), functionally dependent (61.4%) and retired/disabled (73.1%). Median age was 75 years and median duration of disease 11 years. Half the patients were on insulin-based therapy and 30.1% on secretagogue-based therapy. Approximately 57% of patients needed occasional/full assistance to manage the disease. The most frequent risk factor for hypoglycemia was polypharmacy (85.0%). Hypoglycemia in the 12 months before admission was higher in insulin-based therapy patients (66.1%; p = 0.001). Conclusions Hyperglycemic emergencies are the most frequent cause of hospitalization in Portugal, although severe hypoglycemic events represent a health and social problem in elderly/frail patients. There is still the need to optimize therapy in terms of the potential for hypoglycemia in this patient group and a review of anti-hyperglycemic agents to add on to insulin.BioMed CentralSapientiaAlão, SílviaConceição, JoãoDores, JorgeSantos, LèlitaAraújo, FranciscoPape, EstevãoReis, MónicaChipepo, ÁrciaNascimento, EditeBaptista, Ana CatarinaPires, VanessaMarques, CarlosLages, Adriana D SPelicano-Romano, Joãode Jesus, Paula M2021-02-04T16:12:01Z2021-01-052021-02-01T04:14:49Z2021-01-05T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.1/15041engClinical Diabetes and Endocrinology. 2021 Jan 05;7(1):210.1186/s40842-020-00114-3info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-24T10:27:23Zoai:sapientia.ualg.pt:10400.1/15041Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T20:05:56.028201Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study |
title |
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study |
spellingShingle |
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study Alão, Sílvia Diabetes Hypoglycemic episodes Inpatients |
title_short |
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study |
title_full |
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study |
title_fullStr |
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study |
title_full_unstemmed |
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study |
title_sort |
Hypoglycemic episodes in hospitalized people with diabetes in Portugal: the HIPOS-WARD study |
author |
Alão, Sílvia |
author_facet |
Alão, Sílvia Conceição, João Dores, Jorge Santos, Lèlita Araújo, Francisco Pape, Estevão Reis, Mónica Chipepo, Árcia Nascimento, Edite Baptista, Ana Catarina Pires, Vanessa Marques, Carlos Lages, Adriana D S Pelicano-Romano, João de Jesus, Paula M |
author_role |
author |
author2 |
Conceição, João Dores, Jorge Santos, Lèlita Araújo, Francisco Pape, Estevão Reis, Mónica Chipepo, Árcia Nascimento, Edite Baptista, Ana Catarina Pires, Vanessa Marques, Carlos Lages, Adriana D S Pelicano-Romano, João de Jesus, Paula M |
author2_role |
author author author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
Sapientia |
dc.contributor.author.fl_str_mv |
Alão, Sílvia Conceição, João Dores, Jorge Santos, Lèlita Araújo, Francisco Pape, Estevão Reis, Mónica Chipepo, Árcia Nascimento, Edite Baptista, Ana Catarina Pires, Vanessa Marques, Carlos Lages, Adriana D S Pelicano-Romano, João de Jesus, Paula M |
dc.subject.por.fl_str_mv |
Diabetes Hypoglycemic episodes Inpatients |
topic |
Diabetes Hypoglycemic episodes Inpatients |
description |
Background We intended to estimate the proportion hypoglycemic/hyperglycemic emergency episodes in treated diabetes mellitus (DM) patients admitted to a hospital ward, and calculate the prevalence of risk factors for hypoglycemia and diabetic complications. Methods In this cross-sectional, multicentered study, the observational data was collected by physicians from patient’s hospitalization to discharge/death. Statistical tests were 2-tailed considering 5% significance level. Results There were 646 ward admissions due to hyperglycemic emergencies and 176 hypoglycemic episodes with a ratio hypoglycemia/hyperglycemia 0.27 for all DM patients. In T2DM patients the ratio was 0.38. These were mainly female (55.1%), functionally dependent (61.4%) and retired/disabled (73.1%). Median age was 75 years and median duration of disease 11 years. Half the patients were on insulin-based therapy and 30.1% on secretagogue-based therapy. Approximately 57% of patients needed occasional/full assistance to manage the disease. The most frequent risk factor for hypoglycemia was polypharmacy (85.0%). Hypoglycemia in the 12 months before admission was higher in insulin-based therapy patients (66.1%; p = 0.001). Conclusions Hyperglycemic emergencies are the most frequent cause of hospitalization in Portugal, although severe hypoglycemic events represent a health and social problem in elderly/frail patients. There is still the need to optimize therapy in terms of the potential for hypoglycemia in this patient group and a review of anti-hyperglycemic agents to add on to insulin. |
publishDate |
2021 |
dc.date.none.fl_str_mv |
2021-02-04T16:12:01Z 2021-01-05 2021-02-01T04:14:49Z 2021-01-05T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.1/15041 |
url |
http://hdl.handle.net/10400.1/15041 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Clinical Diabetes and Endocrinology. 2021 Jan 05;7(1):2 10.1186/s40842-020-00114-3 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
BioMed Central |
publisher.none.fl_str_mv |
BioMed Central |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799133299756498944 |