Lung cancer samples preserved in liquid medium: One step beyond cytology

Detalhes bibliográficos
Autor(a) principal: Mariano, Vânia Sammartino
Data de Publicação: 2017
Outros Autores: Leal, Letícia Ferro, Pastrez, Paula Roberta Aguiar, Silva, Estela Maria, Reis, R. M., Longatto, Adhemar
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/49833
Resumo: Lung cancer is one of the most common cancer types in men and women worldwide with a high mortality rate. World Health Organization (WHO) classification has accepted biopsy as the primary sample for lung cancer diagnosis, pathological classification and molecular testing for management of patients, yet, the use of alternative sampling procedures is highly encouraged. Bronchial cytological samples require a less invasive collection technique and may be suitable for pathological and molecular analysis and storage in liquid medium. Furthermore, the molecular analysis of bronchial cytological samples allows the detection of molecular biomarkers, which may be useful for the selection of molecular targeted therapies. Thus, the purpose of this review is to describe the usefulness of bronchial cytological samples preserved in liquid medium from lung cancer patients for pathological diagnosis and molecular investigation.
id RCAP_8bb726314ede5126d429a0beb86309ad
oai_identifier_str oai:repositorium.sdum.uminho.pt:1822/49833
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Lung cancer samples preserved in liquid medium: One step beyond cytologyBronchial cytologyLiquid mediumLung cancerMolecular biomarkersCiências Médicas::Medicina BásicaScience & TechnologyLung cancer is one of the most common cancer types in men and women worldwide with a high mortality rate. World Health Organization (WHO) classification has accepted biopsy as the primary sample for lung cancer diagnosis, pathological classification and molecular testing for management of patients, yet, the use of alternative sampling procedures is highly encouraged. Bronchial cytological samples require a less invasive collection technique and may be suitable for pathological and molecular analysis and storage in liquid medium. Furthermore, the molecular analysis of bronchial cytological samples allows the detection of molecular biomarkers, which may be useful for the selection of molecular targeted therapies. Thus, the purpose of this review is to describe the usefulness of bronchial cytological samples preserved in liquid medium from lung cancer patients for pathological diagnosis and molecular investigation.Rui Manuel Reis and Adhemar Longatto-Filho have a Brazilian National Counsel of Technological and Scientific Development (CNPq) Produtivity scholarship.info:eu-repo/semantics/publishedVersionWileyUniversidade do MinhoMariano, Vânia SammartinoLeal, Letícia FerroPastrez, Paula Roberta AguiarSilva, Estela MariaReis, R. M.Longatto, Adhemar2017-10-282017-10-28T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/49833engMariano, V. S., Leal, L. F., Pastrez, P. R. A., Silva, E. M., Reis, R. M., & Longatto‐Filho, A. (2017). Lung cancer samples preserved in liquid medium: One step beyond cytology. Diagnostic cytopathology, 45(10), 915-9218755-103910.1002/dc.2374328589673http://onlinelibrary.wiley.com/doi/10.1002/dc.23743/fullinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T11:59:38Zoai:repositorium.sdum.uminho.pt:1822/49833Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:49:27.461986Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Lung cancer samples preserved in liquid medium: One step beyond cytology
title Lung cancer samples preserved in liquid medium: One step beyond cytology
spellingShingle Lung cancer samples preserved in liquid medium: One step beyond cytology
Mariano, Vânia Sammartino
Bronchial cytology
Liquid medium
Lung cancer
Molecular biomarkers
Ciências Médicas::Medicina Básica
Science & Technology
title_short Lung cancer samples preserved in liquid medium: One step beyond cytology
title_full Lung cancer samples preserved in liquid medium: One step beyond cytology
title_fullStr Lung cancer samples preserved in liquid medium: One step beyond cytology
title_full_unstemmed Lung cancer samples preserved in liquid medium: One step beyond cytology
title_sort Lung cancer samples preserved in liquid medium: One step beyond cytology
author Mariano, Vânia Sammartino
author_facet Mariano, Vânia Sammartino
Leal, Letícia Ferro
Pastrez, Paula Roberta Aguiar
Silva, Estela Maria
Reis, R. M.
Longatto, Adhemar
author_role author
author2 Leal, Letícia Ferro
Pastrez, Paula Roberta Aguiar
Silva, Estela Maria
Reis, R. M.
Longatto, Adhemar
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Mariano, Vânia Sammartino
Leal, Letícia Ferro
Pastrez, Paula Roberta Aguiar
Silva, Estela Maria
Reis, R. M.
Longatto, Adhemar
dc.subject.por.fl_str_mv Bronchial cytology
Liquid medium
Lung cancer
Molecular biomarkers
Ciências Médicas::Medicina Básica
Science & Technology
topic Bronchial cytology
Liquid medium
Lung cancer
Molecular biomarkers
Ciências Médicas::Medicina Básica
Science & Technology
description Lung cancer is one of the most common cancer types in men and women worldwide with a high mortality rate. World Health Organization (WHO) classification has accepted biopsy as the primary sample for lung cancer diagnosis, pathological classification and molecular testing for management of patients, yet, the use of alternative sampling procedures is highly encouraged. Bronchial cytological samples require a less invasive collection technique and may be suitable for pathological and molecular analysis and storage in liquid medium. Furthermore, the molecular analysis of bronchial cytological samples allows the detection of molecular biomarkers, which may be useful for the selection of molecular targeted therapies. Thus, the purpose of this review is to describe the usefulness of bronchial cytological samples preserved in liquid medium from lung cancer patients for pathological diagnosis and molecular investigation.
publishDate 2017
dc.date.none.fl_str_mv 2017-10-28
2017-10-28T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/49833
url http://hdl.handle.net/1822/49833
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Mariano, V. S., Leal, L. F., Pastrez, P. R. A., Silva, E. M., Reis, R. M., & Longatto‐Filho, A. (2017). Lung cancer samples preserved in liquid medium: One step beyond cytology. Diagnostic cytopathology, 45(10), 915-921
8755-1039
10.1002/dc.23743
28589673
http://onlinelibrary.wiley.com/doi/10.1002/dc.23743/full
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Wiley
publisher.none.fl_str_mv Wiley
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
_version_ 1799132259691790336

Registros relacionados