Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.

Detalhes bibliográficos
Autor(a) principal: Pinto, Sara
Data de Publicação: 2013
Outros Autores: Costa, João, Vaz Carneiro, António, Fernandes, Ricardo
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5053
Resumo: Acute otitis media is one of the most common infections in children and one of the leading causes for antibiotic prescription. In this paper, we assess and comment the Cochrane systematic review 'Antibiotics for acute otitis media in children', which aimed at assessing the efficacy and safety of antibiotics for acute otitis media in children and identifying subgroups of children who might benefit more than others from antibiotic treatment. This review showed spontaneous resolution of acute otitis media in most children (82%) and a favorable but modest effect of antibiotics, namely in pain control (number needed to treat to benefit: 20), reduction of tympanic membrane perforations and reduction of contralateral acute otitis media. Adverse effects such as vomiting, diarrhea or rash were more common in the antibiotic group (number needed to treat to harm: 14). Thus, for most children, an expectant observational approach during 48-72h without immediate antibiotic prescription seems justified. An additional meta-analysis found that antibiotics appear to be most useful in children with both acute otitis media and otorrhoea and children under two years of age with bilateral acute otitis media.
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spelling Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.Análise da Revisão Cochrane: Antibioticoterapia na Otite Média Aguda da Criança. Cochrane Database Syst Rev. 2013;1:CD000219.Acute otitis media is one of the most common infections in children and one of the leading causes for antibiotic prescription. In this paper, we assess and comment the Cochrane systematic review 'Antibiotics for acute otitis media in children', which aimed at assessing the efficacy and safety of antibiotics for acute otitis media in children and identifying subgroups of children who might benefit more than others from antibiotic treatment. This review showed spontaneous resolution of acute otitis media in most children (82%) and a favorable but modest effect of antibiotics, namely in pain control (number needed to treat to benefit: 20), reduction of tympanic membrane perforations and reduction of contralateral acute otitis media. Adverse effects such as vomiting, diarrhea or rash were more common in the antibiotic group (number needed to treat to harm: 14). Thus, for most children, an expectant observational approach during 48-72h without immediate antibiotic prescription seems justified. An additional meta-analysis found that antibiotics appear to be most useful in children with both acute otitis media and otorrhoea and children under two years of age with bilateral acute otitis media.A otite média aguda é uma das infeções mais frequentes na criança e um dos principais motivos de prescrição antibiótica. Neste artigo, avaliamos e comentamos a revisão sistemática da Cochrane 'Antibiotics for acute otitis media in children', cujos objetivos eram avaliar a eficácia e a segurança da antibioticoterapia na otite média aguda da criança e identificar subgrupos que mais beneficiem deste tratamento. Esta revisão mostrou resolução espontânea de otite média aguda na maioria dos doentes (82%) e um efeito favorável mas modesto da antibioticoterapia, nomeadamente na resolução da otalgia (number needed to treat to benefit: 20) e na redução das perfurações timpânicas e da otite média aguda contralateral. Observou-se maior risco de efeitos adversos (vómitos, diarreia ou exantema) no grupo da antibioticoterapia (number needed to treat to harm: 14). Assim, parece justificar-se uma atitude de vigilância na maioria das crianças durante 48-72h, sem prescrição antibiótica inicial. Uma meta-análise complementar identificou maior benefício da antibioticoterapia em crianças com otorreia associada a otite média aguda e em crianças menores de 2 anos com otite média aguda bilateral.Ordem dos Médicos2013-12-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5053oai:ojs.www.actamedicaportuguesa.com:article/5053Acta Médica Portuguesa; Vol. 26 No. 6 (2013): November-December; 633-636Acta Médica Portuguesa; Vol. 26 N.º 6 (2013): Novembro-Dezembro; 633-6361646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5053https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5053/3800Pinto, SaraCosta, JoãoVaz Carneiro, AntónioFernandes, Ricardoinfo:eu-repo/semantics/openAccess2022-12-20T11:04:11Zoai:ojs.www.actamedicaportuguesa.com:article/5053Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:01.484543Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.
Análise da Revisão Cochrane: Antibioticoterapia na Otite Média Aguda da Criança. Cochrane Database Syst Rev. 2013;1:CD000219.
title Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.
spellingShingle Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.
Pinto, Sara
title_short Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.
title_full Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.
title_fullStr Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.
title_full_unstemmed Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.
title_sort Analysis of the Cochrane Review: Antibiotics for Acute Otitis Media in Children. Cochrane Database Syst Rev. 2013;1:CD000219.
author Pinto, Sara
author_facet Pinto, Sara
Costa, João
Vaz Carneiro, António
Fernandes, Ricardo
author_role author
author2 Costa, João
Vaz Carneiro, António
Fernandes, Ricardo
author2_role author
author
author
dc.contributor.author.fl_str_mv Pinto, Sara
Costa, João
Vaz Carneiro, António
Fernandes, Ricardo
description Acute otitis media is one of the most common infections in children and one of the leading causes for antibiotic prescription. In this paper, we assess and comment the Cochrane systematic review 'Antibiotics for acute otitis media in children', which aimed at assessing the efficacy and safety of antibiotics for acute otitis media in children and identifying subgroups of children who might benefit more than others from antibiotic treatment. This review showed spontaneous resolution of acute otitis media in most children (82%) and a favorable but modest effect of antibiotics, namely in pain control (number needed to treat to benefit: 20), reduction of tympanic membrane perforations and reduction of contralateral acute otitis media. Adverse effects such as vomiting, diarrhea or rash were more common in the antibiotic group (number needed to treat to harm: 14). Thus, for most children, an expectant observational approach during 48-72h without immediate antibiotic prescription seems justified. An additional meta-analysis found that antibiotics appear to be most useful in children with both acute otitis media and otorrhoea and children under two years of age with bilateral acute otitis media.
publishDate 2013
dc.date.none.fl_str_mv 2013-12-20
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/5053/3800
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 26 No. 6 (2013): November-December; 633-636
Acta Médica Portuguesa; Vol. 26 N.º 6 (2013): Novembro-Dezembro; 633-636
1646-0758
0870-399X
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