Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their quality
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| Publication Date: | 2023 |
| Other Authors: | , , , , , , , , , , |
| Format: | Article |
| Language: | eng |
| Source: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Download full: | http://hdl.handle.net/10451/56203 |
Summary: | Copyright: © 2023 Gabriel et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
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Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their qualityCopyright: © 2023 Gabriel et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.Introduction: Depression is a serious and widespread mental health disorder. A significant proportion of patients with depression fail to remit after two antidepressant treatment trials, a condition named treatment-resistant depression (TRD). Clinical practice guidelines (CPGs) are instruments aimed to improve diagnosis and treatment. This study objective is to systematically appraise the quality and elaborate a comparison of high-quality CPGs with high-quality recommendations aimed at TRD. Methods and analysis: We searched several specialized databases and organizations that develop CPGs. Independent researchers assessed the quality of the CPGs and their recommendations using AGREE II and AGREE-REX instruments, respectively. We selected only high-quality CPGs that included definition and recommendations for TRD. We investigated their divergencies and convergencies as well as weak and strong points. Results: Among seven high-quality CPGs with high-quality recommendations only two (Germany's Nationale Versorgungs Leitlinie-NVL and US Department of Veterans Affairs and Department of Defense-VA/DoD) included specific TRD definition and were selected. We found no convergent therapeutic strategy among these two CPGs. Electroconvulsive therapy is recommended by the NVL but not by the VA/DoD, while repetitive transcranial magnetic stimulation is recommended by the VA/DoD but not by the NVL. While the NVL recommends the use of lithium, and a non-routine use of thyroid or other hormones, psychostimulants, and dopaminergic agents the VA/DoD does not even include these drugs among augmentation strategies. Instead, the VA/DoD recommends ketamine or esketamine as augmentation strategies, while the NVL does not mention these drugs. Other differences between these CPGs include antidepressant combination, psychotherapy as a therapeutic augmentation, and evaluation of the need for hospitalization all of which are only recommended by the NVL. Conclusions: High-quality CPGs for the treatment of depression diverge regarding the definition and use of the term TRD. There is also no convergent approach to TRD from currently high-quality CPGs.F.C.G. is a fellow of the Conselho Nacional de Pesquisa e Tecnologia (CNPq, grant number 141811/2020-0).FrontiersRepositório da Universidade de LisboaGabriel, Franciele CordeiroStein, Airton TetelbomMelo, Daniela de OliveiraFontes-Mota, Gessica Caroline Henriquedos Santos, Itamires BenícioRodrigues, Camila da SilvaDourado, AndreaRodrigues, Mônica CristianeFráguas, RenérioFlorez, Ivan D.Telles-Correia, DiogoRibeiro, Eliane2023-02-07T13:47:24Z20232023-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10451/56203engPLoS One. 2023 Feb 6;18(2):e028150110.1371/journal.pone.02815011932-6203info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-08T17:03:37Zoai:repositorio.ul.pt:10451/56203Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T22:06:43.996907Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their quality |
| title |
Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their quality |
| spellingShingle |
Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their quality Gabriel, Franciele Cordeiro |
| title_short |
Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their quality |
| title_full |
Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their quality |
| title_fullStr |
Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their quality |
| title_full_unstemmed |
Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their quality |
| title_sort |
Guidelines’ recommendations for the treatment-resistant depression: A systematic review of their quality |
| author |
Gabriel, Franciele Cordeiro |
| author_facet |
Gabriel, Franciele Cordeiro Stein, Airton Tetelbom Melo, Daniela de Oliveira Fontes-Mota, Gessica Caroline Henrique dos Santos, Itamires Benício Rodrigues, Camila da Silva Dourado, Andrea Rodrigues, Mônica Cristiane Fráguas, Renério Florez, Ivan D. Telles-Correia, Diogo Ribeiro, Eliane |
| author_role |
author |
| author2 |
Stein, Airton Tetelbom Melo, Daniela de Oliveira Fontes-Mota, Gessica Caroline Henrique dos Santos, Itamires Benício Rodrigues, Camila da Silva Dourado, Andrea Rodrigues, Mônica Cristiane Fráguas, Renério Florez, Ivan D. Telles-Correia, Diogo Ribeiro, Eliane |
| author2_role |
author author author author author author author author author author author |
| dc.contributor.none.fl_str_mv |
Repositório da Universidade de Lisboa |
| dc.contributor.author.fl_str_mv |
Gabriel, Franciele Cordeiro Stein, Airton Tetelbom Melo, Daniela de Oliveira Fontes-Mota, Gessica Caroline Henrique dos Santos, Itamires Benício Rodrigues, Camila da Silva Dourado, Andrea Rodrigues, Mônica Cristiane Fráguas, Renério Florez, Ivan D. Telles-Correia, Diogo Ribeiro, Eliane |
| description |
Copyright: © 2023 Gabriel et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
| publishDate |
2023 |
| dc.date.none.fl_str_mv |
2023-02-07T13:47:24Z 2023 2023-01-01T00:00:00Z |
| dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
| dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10451/56203 |
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http://hdl.handle.net/10451/56203 |
| dc.language.iso.fl_str_mv |
eng |
| language |
eng |
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PLoS One. 2023 Feb 6;18(2):e0281501 10.1371/journal.pone.0281501 1932-6203 |
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info:eu-repo/semantics/openAccess |
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openAccess |
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application/pdf |
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Frontiers |
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Frontiers |
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reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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