Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solution
Autor(a) principal: | |
---|---|
Data de Publicação: | 2005 |
Outros Autores: | , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | https://hdl.handle.net/1822/2573 |
Resumo: | Blends of corn starch with poly(ethylene-vinylalcohol) copolymer (SEVA-C) have been studied and reported as biodegradable. These materials are known to be sensitive to enzymatic action, evidencing a degradation of the starch phase in α-amylase assays. However, from the physical-chemical point of view the degradation of the blend is mainly associated with the leaching of glycerol, since other compounds are not released and no carbohydrates were found in the degradation solution. Based on these results, the present work attempts to determinate the respective diffusion coefficients. Four different experiments were performed, using samples with different thicknesses that were immersed in a simulated physiological solution. High performance liquid chromatography (HPLC) was used to separate the sugar derivatives and glycerol from the degradation solutions. The obtained data were fitted to an empirical model to allow the estimation of the diffusion coefficient for glycerol and glucose, based on the analytical solution for Fick’s law of diffusion, and a good agreement was found (R² ≈ 1). The glycerol leaches quickly out during the first few days of immersion, stabilizing thereafter, presenting greater diffusion coefficients for thicker samples. As the quantity of saccharides in the solution remains almost invariable along the experiments, this work also confirms that the degradation process is difficult without the action of enzymes. |
id |
RCAP_8ea8960e5c925d4e968ae16b4c49ef5a |
---|---|
oai_identifier_str |
oai:repositorium.sdum.uminho.pt:1822/2573 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solutionScience & TechnologyBlends of corn starch with poly(ethylene-vinylalcohol) copolymer (SEVA-C) have been studied and reported as biodegradable. These materials are known to be sensitive to enzymatic action, evidencing a degradation of the starch phase in α-amylase assays. However, from the physical-chemical point of view the degradation of the blend is mainly associated with the leaching of glycerol, since other compounds are not released and no carbohydrates were found in the degradation solution. Based on these results, the present work attempts to determinate the respective diffusion coefficients. Four different experiments were performed, using samples with different thicknesses that were immersed in a simulated physiological solution. High performance liquid chromatography (HPLC) was used to separate the sugar derivatives and glycerol from the degradation solutions. The obtained data were fitted to an empirical model to allow the estimation of the diffusion coefficient for glycerol and glucose, based on the analytical solution for Fick’s law of diffusion, and a good agreement was found (R² ≈ 1). The glycerol leaches quickly out during the first few days of immersion, stabilizing thereafter, presenting greater diffusion coefficients for thicker samples. As the quantity of saccharides in the solution remains almost invariable along the experiments, this work also confirms that the degradation process is difficult without the action of enzymes.Springer Science+Business MediaUniversidade do MinhoAraújo, M. AlbertaFerreira, Eugénio C.Cunha, A. M.Mota, M.20052005-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/1822/2573eng"Journal of materials science: materials in medicine". ISSN 0957-4530. 16:3 (2005) 239-246.0957-453010.1007/s10856-005-6685-015744615http://www.springerlink.cominfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:21:37Zoai:repositorium.sdum.uminho.pt:1822/2573Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:14:55.024070Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solution |
title |
Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solution |
spellingShingle |
Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solution Araújo, M. Alberta Science & Technology |
title_short |
Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solution |
title_full |
Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solution |
title_fullStr |
Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solution |
title_full_unstemmed |
Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solution |
title_sort |
Determination of diffusion coefficients of glycerol and glucose from starch based thermoplastic compounds on simulated physiological solution |
author |
Araújo, M. Alberta |
author_facet |
Araújo, M. Alberta Ferreira, Eugénio C. Cunha, A. M. Mota, M. |
author_role |
author |
author2 |
Ferreira, Eugénio C. Cunha, A. M. Mota, M. |
author2_role |
author author author |
dc.contributor.none.fl_str_mv |
Universidade do Minho |
dc.contributor.author.fl_str_mv |
Araújo, M. Alberta Ferreira, Eugénio C. Cunha, A. M. Mota, M. |
dc.subject.por.fl_str_mv |
Science & Technology |
topic |
Science & Technology |
description |
Blends of corn starch with poly(ethylene-vinylalcohol) copolymer (SEVA-C) have been studied and reported as biodegradable. These materials are known to be sensitive to enzymatic action, evidencing a degradation of the starch phase in α-amylase assays. However, from the physical-chemical point of view the degradation of the blend is mainly associated with the leaching of glycerol, since other compounds are not released and no carbohydrates were found in the degradation solution. Based on these results, the present work attempts to determinate the respective diffusion coefficients. Four different experiments were performed, using samples with different thicknesses that were immersed in a simulated physiological solution. High performance liquid chromatography (HPLC) was used to separate the sugar derivatives and glycerol from the degradation solutions. The obtained data were fitted to an empirical model to allow the estimation of the diffusion coefficient for glycerol and glucose, based on the analytical solution for Fick’s law of diffusion, and a good agreement was found (R² ≈ 1). The glycerol leaches quickly out during the first few days of immersion, stabilizing thereafter, presenting greater diffusion coefficients for thicker samples. As the quantity of saccharides in the solution remains almost invariable along the experiments, this work also confirms that the degradation process is difficult without the action of enzymes. |
publishDate |
2005 |
dc.date.none.fl_str_mv |
2005 2005-01-01T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
https://hdl.handle.net/1822/2573 |
url |
https://hdl.handle.net/1822/2573 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
"Journal of materials science: materials in medicine". ISSN 0957-4530. 16:3 (2005) 239-246. 0957-4530 10.1007/s10856-005-6685-0 15744615 http://www.springerlink.com |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Springer Science+Business Media |
publisher.none.fl_str_mv |
Springer Science+Business Media |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799132592832774144 |