Autopsy in adults with congenital heart disease (ACHD)
Autor(a) principal: | |
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Data de Publicação: | 2020 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.26/41925 https://doi.org/10.1007/s00428-020-02779-8 |
Resumo: | The adult congenital heart diseases (ACHD) population is exceeding the pediatric congenital heart diseases (CHD) population and is progressively expanding each year, representing more than 90% of patients with CHD. Of these, about 75% have undergone surgical and/or percutaneous intervention for palliation or correction. Autopsy can be a very challenging procedure in ACHD patients. The approach and protocol to be used may vary depending on whether the pathologists are facing native disease without surgical or percutaneous interventions, but with various degrees of cardiac remodeling, or previously palliated or corrected CHD. Moreover, interventions for the same condition have evolved over the last decades, as has perioperative myocardial preservations and postoperative care, with different long-term sequelae depending on the era in which patients were operated on. Careful clinicopathological correlation is, thus, required to assist the pathologist in performing the autopsy and reaching a diagnosis regarding the cause of death. Due to the heterogeneity of the structural abnormalities, and the wide variety of surgical and interventional procedures, there are no standard methods for dissecting the heart at autopsy. In this paper, we describe the most common types of CHDs that a pathologist could encounter at autopsy, including the various types of surgical and percutaneous procedures and major pathological manifestations. We also propose a practical systematic approach to the autopsy of ACHD patients. |
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Autopsy in adults with congenital heart disease (ACHD)AutopsyCardiovascular pathologyCongenital heart diseasesAdult congenital heart diseasesProtocolThe adult congenital heart diseases (ACHD) population is exceeding the pediatric congenital heart diseases (CHD) population and is progressively expanding each year, representing more than 90% of patients with CHD. Of these, about 75% have undergone surgical and/or percutaneous intervention for palliation or correction. Autopsy can be a very challenging procedure in ACHD patients. The approach and protocol to be used may vary depending on whether the pathologists are facing native disease without surgical or percutaneous interventions, but with various degrees of cardiac remodeling, or previously palliated or corrected CHD. Moreover, interventions for the same condition have evolved over the last decades, as has perioperative myocardial preservations and postoperative care, with different long-term sequelae depending on the era in which patients were operated on. Careful clinicopathological correlation is, thus, required to assist the pathologist in performing the autopsy and reaching a diagnosis regarding the cause of death. Due to the heterogeneity of the structural abnormalities, and the wide variety of surgical and interventional procedures, there are no standard methods for dissecting the heart at autopsy. In this paper, we describe the most common types of CHDs that a pathologist could encounter at autopsy, including the various types of surgical and percutaneous procedures and major pathological manifestations. We also propose a practical systematic approach to the autopsy of ACHD patients.info:eu-repo/semantics/publishedVersionSpringer Verlag2022-10-14T11:27:22Z2022-10-142020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10400.26/41925http://hdl.handle.net/10400.26/41925https://doi.org/10.1007/s00428-020-02779-8engAngelini, A., di Gioia, C., Doran, H., Fedrigo, M., Henriques de Gouveia, R., Ho, S. Y., Leone, O., Sheppard, M. N., Thiene, G., Dimopoulos, K., Mulder, B., Padalino, M., van der Wal, A. C., & Association for European Cardiovascular Pathology (AECVP) (2020). Autopsy in adults with congenital heart disease (ACHD). Virchows Archiv : an international journal of pathology, 476(6), 797–8201432-2307https://link.springer.com/article/10.1007/s00428-020-02779-8http://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessAngelini, Annalisadi Gioia, CiraDoran, HelenFedrigo, MarnyHenriques de Gouveia, RosaHo, Siew YenLeone, OrnellaSheppard, Mary NThiene, GaetanoDimopoulos, KonstantinosMulder, BarbaraPadalino, Massimovan der Wal, Allard Creponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-02-03T04:22:09Zoai:comum.rcaap.pt:10400.26/41925Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T02:07:44.444485Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Autopsy in adults with congenital heart disease (ACHD) |
title |
Autopsy in adults with congenital heart disease (ACHD) |
spellingShingle |
Autopsy in adults with congenital heart disease (ACHD) Angelini, Annalisa Autopsy Cardiovascular pathology Congenital heart diseases Adult congenital heart diseases Protocol |
title_short |
Autopsy in adults with congenital heart disease (ACHD) |
title_full |
Autopsy in adults with congenital heart disease (ACHD) |
title_fullStr |
Autopsy in adults with congenital heart disease (ACHD) |
title_full_unstemmed |
Autopsy in adults with congenital heart disease (ACHD) |
title_sort |
Autopsy in adults with congenital heart disease (ACHD) |
author |
Angelini, Annalisa |
author_facet |
Angelini, Annalisa di Gioia, Cira Doran, Helen Fedrigo, Marny Henriques de Gouveia, Rosa Ho, Siew Yen Leone, Ornella Sheppard, Mary N Thiene, Gaetano Dimopoulos, Konstantinos Mulder, Barbara Padalino, Massimo van der Wal, Allard C |
author_role |
author |
author2 |
di Gioia, Cira Doran, Helen Fedrigo, Marny Henriques de Gouveia, Rosa Ho, Siew Yen Leone, Ornella Sheppard, Mary N Thiene, Gaetano Dimopoulos, Konstantinos Mulder, Barbara Padalino, Massimo van der Wal, Allard C |
author2_role |
author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Angelini, Annalisa di Gioia, Cira Doran, Helen Fedrigo, Marny Henriques de Gouveia, Rosa Ho, Siew Yen Leone, Ornella Sheppard, Mary N Thiene, Gaetano Dimopoulos, Konstantinos Mulder, Barbara Padalino, Massimo van der Wal, Allard C |
dc.subject.por.fl_str_mv |
Autopsy Cardiovascular pathology Congenital heart diseases Adult congenital heart diseases Protocol |
topic |
Autopsy Cardiovascular pathology Congenital heart diseases Adult congenital heart diseases Protocol |
description |
The adult congenital heart diseases (ACHD) population is exceeding the pediatric congenital heart diseases (CHD) population and is progressively expanding each year, representing more than 90% of patients with CHD. Of these, about 75% have undergone surgical and/or percutaneous intervention for palliation or correction. Autopsy can be a very challenging procedure in ACHD patients. The approach and protocol to be used may vary depending on whether the pathologists are facing native disease without surgical or percutaneous interventions, but with various degrees of cardiac remodeling, or previously palliated or corrected CHD. Moreover, interventions for the same condition have evolved over the last decades, as has perioperative myocardial preservations and postoperative care, with different long-term sequelae depending on the era in which patients were operated on. Careful clinicopathological correlation is, thus, required to assist the pathologist in performing the autopsy and reaching a diagnosis regarding the cause of death. Due to the heterogeneity of the structural abnormalities, and the wide variety of surgical and interventional procedures, there are no standard methods for dissecting the heart at autopsy. In this paper, we describe the most common types of CHDs that a pathologist could encounter at autopsy, including the various types of surgical and percutaneous procedures and major pathological manifestations. We also propose a practical systematic approach to the autopsy of ACHD patients. |
publishDate |
2020 |
dc.date.none.fl_str_mv |
2020-01-01T00:00:00Z 2022-10-14T11:27:22Z 2022-10-14 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.26/41925 http://hdl.handle.net/10400.26/41925 https://doi.org/10.1007/s00428-020-02779-8 |
url |
http://hdl.handle.net/10400.26/41925 https://doi.org/10.1007/s00428-020-02779-8 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Angelini, A., di Gioia, C., Doran, H., Fedrigo, M., Henriques de Gouveia, R., Ho, S. Y., Leone, O., Sheppard, M. N., Thiene, G., Dimopoulos, K., Mulder, B., Padalino, M., van der Wal, A. C., & Association for European Cardiovascular Pathology (AECVP) (2020). Autopsy in adults with congenital heart disease (ACHD). Virchows Archiv : an international journal of pathology, 476(6), 797–820 1432-2307 https://link.springer.com/article/10.1007/s00428-020-02779-8 |
dc.rights.driver.fl_str_mv |
http://creativecommons.org/licenses/by/4.0/ info:eu-repo/semantics/openAccess |
rights_invalid_str_mv |
http://creativecommons.org/licenses/by/4.0/ |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
Springer Verlag |
publisher.none.fl_str_mv |
Springer Verlag |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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RCAAP |
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RCAAP |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
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