Monoclonal Antibodies for Multiple Sclerosis Treatment

Detalhes bibliográficos
Autor(a) principal: Palavra, Filipe
Data de Publicação: 2015
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10316/108944
https://doi.org/10.20344/amp.6486
Resumo: Since their introduction in medical therapy, in the last quarter of the 20th century, monoclonal antibodies have gained an increasing importance in the treatment of various diseases. Neurology has been one of the medical specialties benefiting of the therapeutic potential of these monoclonal antibodies and certain neurological conditions may now contain such drugs in their therapeutic algorithms. Multiple sclerosis is one of these diseases and, in addition to the monoclonal antibodies already licensed for clinical use, several others are in development for future utilization in this specific area. The future will certainly pass through this kind of drugs and, in this article, a review of the most relevant data related to monoclonal antibodies already in use and also in clinical development for multiple sclerosis treatment will be performed.
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spelling Monoclonal Antibodies for Multiple Sclerosis TreatmentAnticorpos Monoclonais para Tratamento da Esclerose MúltiplaAntibodies, MonoclonalClinical TrialsMultiple SclerosisAnticorpos MonoclonaisEnsaios ClínicosEsclerose MúltiplaAntibodies, MonoclonalAntibodies, Monoclonal, HumanizedHumansMultiple SclerosisNervous System DiseasesSince their introduction in medical therapy, in the last quarter of the 20th century, monoclonal antibodies have gained an increasing importance in the treatment of various diseases. Neurology has been one of the medical specialties benefiting of the therapeutic potential of these monoclonal antibodies and certain neurological conditions may now contain such drugs in their therapeutic algorithms. Multiple sclerosis is one of these diseases and, in addition to the monoclonal antibodies already licensed for clinical use, several others are in development for future utilization in this specific area. The future will certainly pass through this kind of drugs and, in this article, a review of the most relevant data related to monoclonal antibodies already in use and also in clinical development for multiple sclerosis treatment will be performed.Desde a sua introdução na terapêutica médica, no último quarto do século XX, os anticorpos monoclonais têm ganho cada vez mais importância no tratamento de várias doenças. A Neurologia tem sido uma das especialidades médicas a beneficiar do potencial terapêutico destes anticorpos monoclonais e algumas doenças neurológicas podem já contar com fármacos deste tipo nos seus algoritmos terapêuticos. A esclerose múltipla é uma dessas doenças e, para além dos já licenciados para utilização clínica, são vários os anticorpos monoclonais que se encontram em desenvolvimento para futura utilização nesta área específica. O futuro passará certamente por fármacos deste tipo e, neste artigo, far-se-á uma revisão dos dados mais relevantes relacionados com os anticorpos monoclonais já em uso e também em desenvolvimento clínico para tratamento da esclerose múltipla.Ordem dos Medicos2015info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/108944http://hdl.handle.net/10316/108944https://doi.org/10.20344/amp.6486eng1646-07580870-399XPalavra, Filipeinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-09-26T08:55:12Zoai:estudogeral.uc.pt:10316/108944Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:25:10.704753Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Monoclonal Antibodies for Multiple Sclerosis Treatment
Anticorpos Monoclonais para Tratamento da Esclerose Múltipla
title Monoclonal Antibodies for Multiple Sclerosis Treatment
spellingShingle Monoclonal Antibodies for Multiple Sclerosis Treatment
Palavra, Filipe
Antibodies, Monoclonal
Clinical Trials
Multiple Sclerosis
Anticorpos Monoclonais
Ensaios Clínicos
Esclerose Múltipla
Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Humans
Multiple Sclerosis
Nervous System Diseases
title_short Monoclonal Antibodies for Multiple Sclerosis Treatment
title_full Monoclonal Antibodies for Multiple Sclerosis Treatment
title_fullStr Monoclonal Antibodies for Multiple Sclerosis Treatment
title_full_unstemmed Monoclonal Antibodies for Multiple Sclerosis Treatment
title_sort Monoclonal Antibodies for Multiple Sclerosis Treatment
author Palavra, Filipe
author_facet Palavra, Filipe
author_role author
dc.contributor.author.fl_str_mv Palavra, Filipe
dc.subject.por.fl_str_mv Antibodies, Monoclonal
Clinical Trials
Multiple Sclerosis
Anticorpos Monoclonais
Ensaios Clínicos
Esclerose Múltipla
Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Humans
Multiple Sclerosis
Nervous System Diseases
topic Antibodies, Monoclonal
Clinical Trials
Multiple Sclerosis
Anticorpos Monoclonais
Ensaios Clínicos
Esclerose Múltipla
Antibodies, Monoclonal
Antibodies, Monoclonal, Humanized
Humans
Multiple Sclerosis
Nervous System Diseases
description Since their introduction in medical therapy, in the last quarter of the 20th century, monoclonal antibodies have gained an increasing importance in the treatment of various diseases. Neurology has been one of the medical specialties benefiting of the therapeutic potential of these monoclonal antibodies and certain neurological conditions may now contain such drugs in their therapeutic algorithms. Multiple sclerosis is one of these diseases and, in addition to the monoclonal antibodies already licensed for clinical use, several others are in development for future utilization in this specific area. The future will certainly pass through this kind of drugs and, in this article, a review of the most relevant data related to monoclonal antibodies already in use and also in clinical development for multiple sclerosis treatment will be performed.
publishDate 2015
dc.date.none.fl_str_mv 2015
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10316/108944
http://hdl.handle.net/10316/108944
https://doi.org/10.20344/amp.6486
url http://hdl.handle.net/10316/108944
https://doi.org/10.20344/amp.6486
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1646-0758
0870-399X
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Ordem dos Medicos
publisher.none.fl_str_mv Ordem dos Medicos
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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