Diagnosis and treatment of keratoacanthoma in the lower lip: A case report

Detalhes bibliográficos
Autor(a) principal: Santos,Thamiles Rodrigues dos
Data de Publicação: 2024
Outros Autores: Farias,Jener Gonçalves de, Hassam,Sheinaz Farias, Oliveira,Marcio Campos de, Valente,Alessandra Laís Pinho
Tipo de documento: Relatório
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-28902024000300136
Resumo: Abstract Keratoacanthoma diagnosis is challenging, and therefore, this publication contributes to the current literature by presenting epidemiological data and describing clinical and histopathological characteristics and the treatment decision. A 69-year-old Caucasian male patient presented with a well-delimited exophytic growth nodule in the lower lip measuring 10 millimeters with circular shape, firm consistency, pink color, and rough surface. The clinical suspicion was squamous cell carcinoma. An incisional biopsy and histopathological analysis were performed, which revealed fragments of oral mucosa lined by hyperparakeratinized stratified squamous epithelium with a center filled with keratin, corneal pearls, pseudoepitheliomatous hyperplasia, and areas of epithelial dysplasia. The diagnosis of keratoacanthoma was determined. Surgical resection was performed, completely removing the lesion, and histopathological analysis confirmed the diagnosis of keratoacanthoma. The fact that the patient was male, over 45 years old, and Caucasian agrees with the epidemiology of the population most affected by keratoacanthoma. The histopathology of the case corroborates the classic characterization, mainly the central depression filled with keratin. The treatment chosen was surgical resection with a small margin of safety, according to the current literature. Keratoacanthomas are more common in males aged over 45 years and in Caucasian individuals. The main etiology is sun exposure without protective measures. It presents as an exophytic nodule with a firm consistency, rough surface, and center filled with keratin. Histopathology is characterized by a crateriform structure, dyskeratosis, and the presence of corneal pearls. The most indicated treatment is surgical resection.
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spelling Diagnosis and treatment of keratoacanthoma in the lower lip: A case reportBiopsyKeratoacanthomaLip neoplasmsAbstract Keratoacanthoma diagnosis is challenging, and therefore, this publication contributes to the current literature by presenting epidemiological data and describing clinical and histopathological characteristics and the treatment decision. A 69-year-old Caucasian male patient presented with a well-delimited exophytic growth nodule in the lower lip measuring 10 millimeters with circular shape, firm consistency, pink color, and rough surface. The clinical suspicion was squamous cell carcinoma. An incisional biopsy and histopathological analysis were performed, which revealed fragments of oral mucosa lined by hyperparakeratinized stratified squamous epithelium with a center filled with keratin, corneal pearls, pseudoepitheliomatous hyperplasia, and areas of epithelial dysplasia. The diagnosis of keratoacanthoma was determined. Surgical resection was performed, completely removing the lesion, and histopathological analysis confirmed the diagnosis of keratoacanthoma. The fact that the patient was male, over 45 years old, and Caucasian agrees with the epidemiology of the population most affected by keratoacanthoma. The histopathology of the case corroborates the classic characterization, mainly the central depression filled with keratin. The treatment chosen was surgical resection with a small margin of safety, according to the current literature. Keratoacanthomas are more common in males aged over 45 years and in Caucasian individuals. The main etiology is sun exposure without protective measures. It presents as an exophytic nodule with a firm consistency, rough surface, and center filled with keratin. Histopathology is characterized by a crateriform structure, dyskeratosis, and the presence of corneal pearls. The most indicated treatment is surgical resection.Sociedade Portuguesa de Estomatologia e Medicina Dentária2024-09-01info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/reporttext/htmlhttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-28902024000300136Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial v.65 n.3 2024reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttp://scielo.pt/scielo.php?script=sci_arttext&pid=S1646-28902024000300136Santos,Thamiles Rodrigues dosFarias,Jener Gonçalves deHassam,Sheinaz FariasOliveira,Marcio Campos deValente,Alessandra Laís Pinhoinfo:eu-repo/semantics/openAccess2024-11-07T23:00:51Zoai:scielo:S1646-28902024000300136Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-11-07T23:00:51Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Diagnosis and treatment of keratoacanthoma in the lower lip: A case report
title Diagnosis and treatment of keratoacanthoma in the lower lip: A case report
spellingShingle Diagnosis and treatment of keratoacanthoma in the lower lip: A case report
Santos,Thamiles Rodrigues dos
Biopsy
Keratoacanthoma
Lip neoplasms
title_short Diagnosis and treatment of keratoacanthoma in the lower lip: A case report
title_full Diagnosis and treatment of keratoacanthoma in the lower lip: A case report
title_fullStr Diagnosis and treatment of keratoacanthoma in the lower lip: A case report
title_full_unstemmed Diagnosis and treatment of keratoacanthoma in the lower lip: A case report
title_sort Diagnosis and treatment of keratoacanthoma in the lower lip: A case report
author Santos,Thamiles Rodrigues dos
author_facet Santos,Thamiles Rodrigues dos
Farias,Jener Gonçalves de
Hassam,Sheinaz Farias
Oliveira,Marcio Campos de
Valente,Alessandra Laís Pinho
author_role author
author2 Farias,Jener Gonçalves de
Hassam,Sheinaz Farias
Oliveira,Marcio Campos de
Valente,Alessandra Laís Pinho
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Santos,Thamiles Rodrigues dos
Farias,Jener Gonçalves de
Hassam,Sheinaz Farias
Oliveira,Marcio Campos de
Valente,Alessandra Laís Pinho
dc.subject.por.fl_str_mv Biopsy
Keratoacanthoma
Lip neoplasms
topic Biopsy
Keratoacanthoma
Lip neoplasms
description Abstract Keratoacanthoma diagnosis is challenging, and therefore, this publication contributes to the current literature by presenting epidemiological data and describing clinical and histopathological characteristics and the treatment decision. A 69-year-old Caucasian male patient presented with a well-delimited exophytic growth nodule in the lower lip measuring 10 millimeters with circular shape, firm consistency, pink color, and rough surface. The clinical suspicion was squamous cell carcinoma. An incisional biopsy and histopathological analysis were performed, which revealed fragments of oral mucosa lined by hyperparakeratinized stratified squamous epithelium with a center filled with keratin, corneal pearls, pseudoepitheliomatous hyperplasia, and areas of epithelial dysplasia. The diagnosis of keratoacanthoma was determined. Surgical resection was performed, completely removing the lesion, and histopathological analysis confirmed the diagnosis of keratoacanthoma. The fact that the patient was male, over 45 years old, and Caucasian agrees with the epidemiology of the population most affected by keratoacanthoma. The histopathology of the case corroborates the classic characterization, mainly the central depression filled with keratin. The treatment chosen was surgical resection with a small margin of safety, according to the current literature. Keratoacanthomas are more common in males aged over 45 years and in Caucasian individuals. The main etiology is sun exposure without protective measures. It presents as an exophytic nodule with a firm consistency, rough surface, and center filled with keratin. Histopathology is characterized by a crateriform structure, dyskeratosis, and the presence of corneal pearls. The most indicated treatment is surgical resection.
publishDate 2024
dc.date.none.fl_str_mv 2024-09-01
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
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format report
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dc.language.iso.fl_str_mv eng
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dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
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dc.format.none.fl_str_mv text/html
dc.publisher.none.fl_str_mv Sociedade Portuguesa de Estomatologia e Medicina Dentária
publisher.none.fl_str_mv Sociedade Portuguesa de Estomatologia e Medicina Dentária
dc.source.none.fl_str_mv Revista Portuguesa de Estomatologia, Medicina Dentária e Cirurgia Maxilofacial v.65 n.3 2024
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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