Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series?
Autor(a) principal: | |
---|---|
Data de Publicação: | 2006 |
Outros Autores: | , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.4/729 |
Resumo: | Mercaptobenzothiazole (MBT) compounds are well known contact allergens. To detect rubber allergic patients we use both MBT (2% in petrolatum) and a mercapto-mix with 4 constituents of 0.5% each in our standard series. In this article the EECDRG presents data of in total 32,475 consecutive tested patients attending the respective contact dermatitis clinics from 11 centres in Europe to determine if the mix and MBT detected the same allergic patients. We found 327 patients positive to the mix or MBT, or to both. 261 were positive to the mix and 254 to MBT. MBT was negative in 73 patients who were positive to the mix. If the mix had not been in the standard series, on average 22% of patients allergic to a mercapto-compound would have been missed, for MBT this would have been on average 20%. All clinics would have missed a significant number of positive reactions if both compounds had not been tested. We conclude, that both the mercapto mix and MBT are required in the standard series. |
id |
RCAP_8f7529f8d13ebfbdb8077c957cf12498 |
---|---|
oai_identifier_str |
oai:rihuc.huc.min-saude.pt:10400.4/729 |
network_acronym_str |
RCAP |
network_name_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository_id_str |
7160 |
spelling |
Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series?Dermatite de ContactoTestes CutâneosMercaptobenzothiazole (MBT) compounds are well known contact allergens. To detect rubber allergic patients we use both MBT (2% in petrolatum) and a mercapto-mix with 4 constituents of 0.5% each in our standard series. In this article the EECDRG presents data of in total 32,475 consecutive tested patients attending the respective contact dermatitis clinics from 11 centres in Europe to determine if the mix and MBT detected the same allergic patients. We found 327 patients positive to the mix or MBT, or to both. 261 were positive to the mix and 254 to MBT. MBT was negative in 73 patients who were positive to the mix. If the mix had not been in the standard series, on average 22% of patients allergic to a mercapto-compound would have been missed, for MBT this would have been on average 20%. All clinics would have missed a significant number of positive reactions if both compounds had not been tested. We conclude, that both the mercapto mix and MBT are required in the standard series.WileyRIHUCDiepgen, TBruynzeel, DPAndersen, KEBrandão, FMBruze, MGonçalo, MargaridaGoossens, ALathi, AMahler, VMenné, TWhite, IRWilkinson, JDEuropean Environmental Contact Dermatitis Research Group (EECDRG)2010-03-02T15:49:09Z20062006-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.4/729engContact Dermatitis. 2006 Jul;55(1):36-8.info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-11T14:21:54Zoai:rihuc.huc.min-saude.pt:10400.4/729Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:03:17.056637Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series? |
title |
Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series? |
spellingShingle |
Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series? Diepgen, T Dermatite de Contacto Testes Cutâneos |
title_short |
Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series? |
title_full |
Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series? |
title_fullStr |
Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series? |
title_full_unstemmed |
Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series? |
title_sort |
Mercaptobenzothiazole or the mercapto-mix: which should be in the standard series? |
author |
Diepgen, T |
author_facet |
Diepgen, T Bruynzeel, DP Andersen, KE Brandão, FM Bruze, M Gonçalo, Margarida Goossens, A Lathi, A Mahler, V Menné, T White, IR Wilkinson, JD European Environmental Contact Dermatitis Research Group (EECDRG) |
author_role |
author |
author2 |
Bruynzeel, DP Andersen, KE Brandão, FM Bruze, M Gonçalo, Margarida Goossens, A Lathi, A Mahler, V Menné, T White, IR Wilkinson, JD European Environmental Contact Dermatitis Research Group (EECDRG) |
author2_role |
author author author author author author author author author author author author |
dc.contributor.none.fl_str_mv |
RIHUC |
dc.contributor.author.fl_str_mv |
Diepgen, T Bruynzeel, DP Andersen, KE Brandão, FM Bruze, M Gonçalo, Margarida Goossens, A Lathi, A Mahler, V Menné, T White, IR Wilkinson, JD European Environmental Contact Dermatitis Research Group (EECDRG) |
dc.subject.por.fl_str_mv |
Dermatite de Contacto Testes Cutâneos |
topic |
Dermatite de Contacto Testes Cutâneos |
description |
Mercaptobenzothiazole (MBT) compounds are well known contact allergens. To detect rubber allergic patients we use both MBT (2% in petrolatum) and a mercapto-mix with 4 constituents of 0.5% each in our standard series. In this article the EECDRG presents data of in total 32,475 consecutive tested patients attending the respective contact dermatitis clinics from 11 centres in Europe to determine if the mix and MBT detected the same allergic patients. We found 327 patients positive to the mix or MBT, or to both. 261 were positive to the mix and 254 to MBT. MBT was negative in 73 patients who were positive to the mix. If the mix had not been in the standard series, on average 22% of patients allergic to a mercapto-compound would have been missed, for MBT this would have been on average 20%. All clinics would have missed a significant number of positive reactions if both compounds had not been tested. We conclude, that both the mercapto mix and MBT are required in the standard series. |
publishDate |
2006 |
dc.date.none.fl_str_mv |
2006 2006-01-01T00:00:00Z 2010-03-02T15:49:09Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.4/729 |
url |
http://hdl.handle.net/10400.4/729 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
Contact Dermatitis. 2006 Jul;55(1):36-8. |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.publisher.none.fl_str_mv |
Wiley |
publisher.none.fl_str_mv |
Wiley |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
|
_version_ |
1799131696939925504 |