Miliary tuberculosis – A challenging diagnosis

Detalhes bibliográficos
Autor(a) principal: Pinto Silva, Catarina
Data de Publicação: 2024
Outros Autores: de Sousa, Beatriz, Lima, Joana, Vasconcelos, Sofia, Rebelo, Alícia, Lobo, Ana Luísa, Fernandes, Alexandre
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.25753/BirthGrowthMJ.v33.i3.27681
Resumo: Tuberculosis is a challenging diagnosis with marked clinical heterogeneity that can lead to diagnostic delay and serious and potentially life-threatening problems. The most prevalent form of the disease is pulmonary tuberculosis. The present case has unique features as in that it describes a case of miliary tuberculosis in an immunocompetent adolescent vaccinated with the Bacillus Calmette-Guerin vaccine and raises awareness of the occurrence of normal radiograph and early in the course of pulmonary tuberculosis, and normal head tomography even in the presence of tuberculous meningitis, highlighting the need for a high index of suspicion. It also shows that tuberculosis should be included in the differential diagnosis of fever of unknown origin with weight loss, even when no epidemiologic link has been established.
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spelling Miliary tuberculosis – A challenging diagnosisTuberculose miliar - Um diagnóstico desafianteCase ReportsTuberculosis is a challenging diagnosis with marked clinical heterogeneity that can lead to diagnostic delay and serious and potentially life-threatening problems. The most prevalent form of the disease is pulmonary tuberculosis. The present case has unique features as in that it describes a case of miliary tuberculosis in an immunocompetent adolescent vaccinated with the Bacillus Calmette-Guerin vaccine and raises awareness of the occurrence of normal radiograph and early in the course of pulmonary tuberculosis, and normal head tomography even in the presence of tuberculous meningitis, highlighting the need for a high index of suspicion. It also shows that tuberculosis should be included in the differential diagnosis of fever of unknown origin with weight loss, even when no epidemiologic link has been established.A tuberculose é uma doença com grande heterogeneidade de apresentações e clinicamente desafiante, o que pode levar a atrasos no diagnóstico com consequências graves e potencialmente fatais. A forma mais prevalente da doença é pulmonar. O caso apresentado tem características únicas, pois descreve um caso de tuberculose miliar numa adolescente imunocompetente vacinada com a vacina do Bacilo de Calmette-Guerin, e pretende alertar para a importância de manter um elevado índice de suspeição perante uma radiografia de tórax normal no início da doença e uma tomografia craniana normal no contexto de meningite tuberculosa. Salienta ainda a importância de considerar a tuberculose no diagnóstico diferencial de febre de origem indeterminada com perda ponderal, mesmo quando não existe uma ligação epidemiológica identificada.Unidade Local de Saúde de Santo António2024-10-22info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttps://doi.org/10.25753/BirthGrowthMJ.v33.i3.27681eng2183-9417Pinto Silva, Catarinade Sousa, BeatrizLima, JoanaVasconcelos, SofiaRebelo, AlíciaLobo, Ana LuísaFernandes, Alexandreinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-10-24T17:00:20Zoai:ojs.revistas.rcaap.pt:article/27681Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-10-24T17:00:20Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Miliary tuberculosis – A challenging diagnosis
Tuberculose miliar - Um diagnóstico desafiante
title Miliary tuberculosis – A challenging diagnosis
spellingShingle Miliary tuberculosis – A challenging diagnosis
Pinto Silva, Catarina
Case Reports
title_short Miliary tuberculosis – A challenging diagnosis
title_full Miliary tuberculosis – A challenging diagnosis
title_fullStr Miliary tuberculosis – A challenging diagnosis
title_full_unstemmed Miliary tuberculosis – A challenging diagnosis
title_sort Miliary tuberculosis – A challenging diagnosis
author Pinto Silva, Catarina
author_facet Pinto Silva, Catarina
de Sousa, Beatriz
Lima, Joana
Vasconcelos, Sofia
Rebelo, Alícia
Lobo, Ana Luísa
Fernandes, Alexandre
author_role author
author2 de Sousa, Beatriz
Lima, Joana
Vasconcelos, Sofia
Rebelo, Alícia
Lobo, Ana Luísa
Fernandes, Alexandre
author2_role author
author
author
author
author
author
dc.contributor.author.fl_str_mv Pinto Silva, Catarina
de Sousa, Beatriz
Lima, Joana
Vasconcelos, Sofia
Rebelo, Alícia
Lobo, Ana Luísa
Fernandes, Alexandre
dc.subject.por.fl_str_mv Case Reports
topic Case Reports
description Tuberculosis is a challenging diagnosis with marked clinical heterogeneity that can lead to diagnostic delay and serious and potentially life-threatening problems. The most prevalent form of the disease is pulmonary tuberculosis. The present case has unique features as in that it describes a case of miliary tuberculosis in an immunocompetent adolescent vaccinated with the Bacillus Calmette-Guerin vaccine and raises awareness of the occurrence of normal radiograph and early in the course of pulmonary tuberculosis, and normal head tomography even in the presence of tuberculous meningitis, highlighting the need for a high index of suspicion. It also shows that tuberculosis should be included in the differential diagnosis of fever of unknown origin with weight loss, even when no epidemiologic link has been established.
publishDate 2024
dc.date.none.fl_str_mv 2024-10-22
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.25753/BirthGrowthMJ.v33.i3.27681
url https://doi.org/10.25753/BirthGrowthMJ.v33.i3.27681
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 2183-9417
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.publisher.none.fl_str_mv Unidade Local de Saúde de Santo António
publisher.none.fl_str_mv Unidade Local de Saúde de Santo António
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
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