Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3
Autor(a) principal: | |
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Data de Publicação: | 2018 |
Outros Autores: | , , , , , , , , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10316/90507 https://doi.org/10.1111/aos.13775 |
Resumo: | Purpose To characterize the lifestyle and nutritional risk profile associated with the Mediterranean diet in a Portuguese population with and without age‐related macular degeneration (AMD). Methods Nested case–control study (n = 883) within the Coimbra Eye Study, including 434 subjects with AMD and 449 age‐ and sex‐matched subjects without AMD. All enrolled subjects underwent a full risk assessment, including lifestyle‐related risk factors and a thorough food frequency questionnaire. This allowed us to build an adherence score to the Mediterranean diet (mediSCORE, range 0–9) constructed from individual food intakes. Food intake was also further analysed by conversion to micronutrient consumption. Results Our results suggest that physical activity has a protective role in AMD [p = 0.018 after multivariate adjustment, OR: 0.69 (0.51–0.93)]. High (mediSCORE ≥6) was also found to be protective [p = 0.041, OR: 0.62 (95% CI: 0.38–0.97)]. Food group analysis unveiled a specific protective role for increased fruits consumption (p = 0.029). Finally, micronutrient analysis revealed a protective role associated with increased consumption of caffeine, fibres, beta‐carotene, vitamin C and vitamin E (p < 0.05). Conclusion High mediSCORE appears to confer protection against the development of AMD in a Mediterranean population. This effect is driven by increased consumption of fruits and some antioxidant micronutrients, which emerged as statistically significant protective factors. Further studies are required to establish dietary recommendations with clinical application. |
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Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3Mediterranean dietage-related macular degenerationepidemiologymicronutrientsnutritionPurpose To characterize the lifestyle and nutritional risk profile associated with the Mediterranean diet in a Portuguese population with and without age‐related macular degeneration (AMD). Methods Nested case–control study (n = 883) within the Coimbra Eye Study, including 434 subjects with AMD and 449 age‐ and sex‐matched subjects without AMD. All enrolled subjects underwent a full risk assessment, including lifestyle‐related risk factors and a thorough food frequency questionnaire. This allowed us to build an adherence score to the Mediterranean diet (mediSCORE, range 0–9) constructed from individual food intakes. Food intake was also further analysed by conversion to micronutrient consumption. Results Our results suggest that physical activity has a protective role in AMD [p = 0.018 after multivariate adjustment, OR: 0.69 (0.51–0.93)]. High (mediSCORE ≥6) was also found to be protective [p = 0.041, OR: 0.62 (95% CI: 0.38–0.97)]. Food group analysis unveiled a specific protective role for increased fruits consumption (p = 0.029). Finally, micronutrient analysis revealed a protective role associated with increased consumption of caffeine, fibres, beta‐carotene, vitamin C and vitamin E (p < 0.05). Conclusion High mediSCORE appears to confer protection against the development of AMD in a Mediterranean population. This effect is driven by increased consumption of fruits and some antioxidant micronutrients, which emerged as statistically significant protective factors. Further studies are required to establish dietary recommendations with clinical application.John Wiley & Sons Ltd2018-12info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articlehttp://hdl.handle.net/10316/90507http://hdl.handle.net/10316/90507https://doi.org/10.1111/aos.13775eng1755-375Xhttps://onlinelibrary.wiley.com/doi/full/10.1111/aos.13775Raimundo, MiguelMira, FilipeCachulo, Maria da LuzBarreto, PatríciaRibeiro, LuísaFarinha, CláudiaLaíns, InêsNunes, SandrinaAlves, DalilaFigueira, JoãoMerle, Bénédicte MjDelcourt, CécileSantos, LèlitaSilva, Rufinoinfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2022-05-25T04:58:30Zoai:estudogeral.uc.pt:10316/90507Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T21:10:37.727145Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3 |
title |
Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3 |
spellingShingle |
Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3 Raimundo, Miguel Mediterranean diet age-related macular degeneration epidemiology micronutrients nutrition |
title_short |
Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3 |
title_full |
Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3 |
title_fullStr |
Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3 |
title_full_unstemmed |
Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3 |
title_sort |
Adherence to a Mediterranean diet, lifestyle and age-related macular degeneration: the Coimbra Eye Study - report 3 |
author |
Raimundo, Miguel |
author_facet |
Raimundo, Miguel Mira, Filipe Cachulo, Maria da Luz Barreto, Patrícia Ribeiro, Luísa Farinha, Cláudia Laíns, Inês Nunes, Sandrina Alves, Dalila Figueira, João Merle, Bénédicte Mj Delcourt, Cécile Santos, Lèlita Silva, Rufino |
author_role |
author |
author2 |
Mira, Filipe Cachulo, Maria da Luz Barreto, Patrícia Ribeiro, Luísa Farinha, Cláudia Laíns, Inês Nunes, Sandrina Alves, Dalila Figueira, João Merle, Bénédicte Mj Delcourt, Cécile Santos, Lèlita Silva, Rufino |
author2_role |
author author author author author author author author author author author author author |
dc.contributor.author.fl_str_mv |
Raimundo, Miguel Mira, Filipe Cachulo, Maria da Luz Barreto, Patrícia Ribeiro, Luísa Farinha, Cláudia Laíns, Inês Nunes, Sandrina Alves, Dalila Figueira, João Merle, Bénédicte Mj Delcourt, Cécile Santos, Lèlita Silva, Rufino |
dc.subject.por.fl_str_mv |
Mediterranean diet age-related macular degeneration epidemiology micronutrients nutrition |
topic |
Mediterranean diet age-related macular degeneration epidemiology micronutrients nutrition |
description |
Purpose To characterize the lifestyle and nutritional risk profile associated with the Mediterranean diet in a Portuguese population with and without age‐related macular degeneration (AMD). Methods Nested case–control study (n = 883) within the Coimbra Eye Study, including 434 subjects with AMD and 449 age‐ and sex‐matched subjects without AMD. All enrolled subjects underwent a full risk assessment, including lifestyle‐related risk factors and a thorough food frequency questionnaire. This allowed us to build an adherence score to the Mediterranean diet (mediSCORE, range 0–9) constructed from individual food intakes. Food intake was also further analysed by conversion to micronutrient consumption. Results Our results suggest that physical activity has a protective role in AMD [p = 0.018 after multivariate adjustment, OR: 0.69 (0.51–0.93)]. High (mediSCORE ≥6) was also found to be protective [p = 0.041, OR: 0.62 (95% CI: 0.38–0.97)]. Food group analysis unveiled a specific protective role for increased fruits consumption (p = 0.029). Finally, micronutrient analysis revealed a protective role associated with increased consumption of caffeine, fibres, beta‐carotene, vitamin C and vitamin E (p < 0.05). Conclusion High mediSCORE appears to confer protection against the development of AMD in a Mediterranean population. This effect is driven by increased consumption of fruits and some antioxidant micronutrients, which emerged as statistically significant protective factors. Further studies are required to establish dietary recommendations with clinical application. |
publishDate |
2018 |
dc.date.none.fl_str_mv |
2018-12 |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10316/90507 http://hdl.handle.net/10316/90507 https://doi.org/10.1111/aos.13775 |
url |
http://hdl.handle.net/10316/90507 https://doi.org/10.1111/aos.13775 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
1755-375X https://onlinelibrary.wiley.com/doi/full/10.1111/aos.13775 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.publisher.none.fl_str_mv |
John Wiley & Sons Ltd |
publisher.none.fl_str_mv |
John Wiley & Sons Ltd |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799134000426516480 |