Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases

Detalhes bibliográficos
Autor(a) principal: Sá, Ângelo
Data de Publicação: 2016
Outros Autores: Azevedo, Leandro Nobre, Cunha, Luísa
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906
Resumo: Introduction: Schwannoma or neurilemmoma is a benign peripheric nerve tumor that usually presents as a slow growing single lesion; it has origin in Schwann cells proliferation. Although it represents a small percentage of the benign tumors of the upper arm, it is the most frequent of neural origin. We present a retrospective study of upper limb schwannomas; our aim is establish the appropriate preoperative approach, to recognise the efficiency of the treatment and the pos-operative follow-up.Material and Methods: Review of 17 patients treated between 2007 and 2014 with upper limb schwannoma and characterization as to age, gender, location in the upper limb, signs and symptoms, pre-operative studies, histologic diagnosis and postoperative surveillance.Results: In four of them the schwannoma was localized on the arm, three on the forearm, four on the wrist and 6 on the hand or fingers. We proceed to careful microsurgical dissection in a bloodless field to optimize the functional final result. The enucleation without fascicular lesion was achieved in 12 patients. In five patients we performed the excision of the fascicles involved by the mass. Nine patients developed paresthesias in the immediate postoperative period, with five of them improving in 12 months. One patient presented motor deficit of the radial nerve with partial recover at 12 monts.Discussion: Schwannomas are rare tumours with well circumscribed morphology. Occasionally it appears in upper limb. The preoperativediagnosis is rarely, so normally the diagnosis is established only after excision and histologic study.Conclusion: Schwannoma should be considered as a diagnostic hypothesis when evaluating subcutaneous nodes associated withneurologic symptoms. It is important to query the presence of paresthesias and perform the Tinel sign, both typical of this condition.Imagiological exams have a scarce contribute in the diagnosis. To improve the final result, the preoperative study must be insightful, being advisable to consider the benefits of the surgery compared to the potential iatrogenic damage to the nerve.
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spelling Schwannoma of the Upper Extremity: Retrospective Analysis of 17 CasesSchwanoma do Membro Superior: Análise Retrospectiva de 17 CasosHandNeurilemmomaSoft Tissue NeoplasmsUpper Extremity.Extremidade SuperiorMãoNeoplasias de Tecidos MolesNeurilemoma.Introduction: Schwannoma or neurilemmoma is a benign peripheric nerve tumor that usually presents as a slow growing single lesion; it has origin in Schwann cells proliferation. Although it represents a small percentage of the benign tumors of the upper arm, it is the most frequent of neural origin. We present a retrospective study of upper limb schwannomas; our aim is establish the appropriate preoperative approach, to recognise the efficiency of the treatment and the pos-operative follow-up.Material and Methods: Review of 17 patients treated between 2007 and 2014 with upper limb schwannoma and characterization as to age, gender, location in the upper limb, signs and symptoms, pre-operative studies, histologic diagnosis and postoperative surveillance.Results: In four of them the schwannoma was localized on the arm, three on the forearm, four on the wrist and 6 on the hand or fingers. We proceed to careful microsurgical dissection in a bloodless field to optimize the functional final result. The enucleation without fascicular lesion was achieved in 12 patients. In five patients we performed the excision of the fascicles involved by the mass. Nine patients developed paresthesias in the immediate postoperative period, with five of them improving in 12 months. One patient presented motor deficit of the radial nerve with partial recover at 12 monts.Discussion: Schwannomas are rare tumours with well circumscribed morphology. Occasionally it appears in upper limb. The preoperativediagnosis is rarely, so normally the diagnosis is established only after excision and histologic study.Conclusion: Schwannoma should be considered as a diagnostic hypothesis when evaluating subcutaneous nodes associated withneurologic symptoms. It is important to query the presence of paresthesias and perform the Tinel sign, both typical of this condition.Imagiological exams have a scarce contribute in the diagnosis. To improve the final result, the preoperative study must be insightful, being advisable to consider the benefits of the surgery compared to the potential iatrogenic damage to the nerve.Introdução: O schwanoma ou neurilemoma é um tumor benigno dos nervos periféricos e apresenta-se habitualmente como uma lesão única de crescimento indolente, com origem na proliferação das células de Schwann. Representa uma pequena percentagem dos tumores benignos do membro superior, contudo é o mais frequente de origem neural. Apresentamos um estudo retrospectivo de schwanomas do membro superior para estabelecer a abordagem pré-operatória adequada, avaliar a eficácia do tratamento e observar a evolução pós-operatória.Material e Métodos: Revisão de 17 doentes tratados desde 2007 a 2014 com schwanoma do membro superior e caracterização quanto à idade, sexo, localização no membro superior, sinais e sintomas, exames pré-operatórios, diagnóstico histológico e vigilância pós-operatória.Resultados: Observou-se que em quatro dos doentes, o schwanoma se localizava no braço, três no antebraço, quatro no punho e seis na mão ou dedos. Procedeu-se a excisão com ampliação óptica para optimização do resultado funcional final. A enucleação foi realizada sem lesão fascicular em 12 doentes. Por sua vez, em cinco doentes efectuou-se a excisão dos fascículos envolvidos pela massa. No pós-operatório imediato as parestesias surgiram em nove doentes, regredindo em cinco daqueles no período pósoperatório de 12 meses. Um doente evidenciou défice motor do nervo radial, com recuperação parcial aos 12 meses.Discussão: Os schwanomas são tumores raros, de morfologia bem delimitada, que atingem esporadicamente o membro superior. O diagnóstico pré operatório é pouco frequente, pelo que normalmente apenas se estabelece o diagnóstico após a excisão e o estudo histopatológico.Conclusão: Os schwanomas deverão ser equacionados nas hipóteses de diagnóstico dos nódulos subcutâneos associados a sintomas neurológicos. Assim, é importante investigar a presença de parestesias e o sinal de Tinel, característicos desta lesão. A imagiologiatem um contributo fruste no diagnóstico. Para melhorar o resultado final, o estudo pré-operatório deverá ser criterioso, sendo aconselhável ponderar o benefício da cirurgia face à potencial lesão iatrogénica do nervo.Ordem dos Médicos2016-09-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/mswordimage/jpegimage/jpegimage/jpegimage/jpegapplication/mswordapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906oai:ojs.www.actamedicaportuguesa.com:article/6906Acta Médica Portuguesa; Vol. 29 No. 9 (2016): September; 519-524Acta Médica Portuguesa; Vol. 29 N.º 9 (2016): Setembro; 519-5241646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/4761https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7842https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7843https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7844https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7845https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7846https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/8034https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/8703Direitos de Autor (c) 2016 Acta Médica Portuguesainfo:eu-repo/semantics/openAccessSá, ÂngeloAzevedo, Leandro NobreCunha, Luísa2022-12-20T11:05:02Zoai:ojs.www.actamedicaportuguesa.com:article/6906Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:19:23.166214Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases
Schwanoma do Membro Superior: Análise Retrospectiva de 17 Casos
title Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases
spellingShingle Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases
Sá, Ângelo
Hand
Neurilemmoma
Soft Tissue Neoplasms
Upper Extremity.
Extremidade Superior
Mão
Neoplasias de Tecidos Moles
Neurilemoma.
title_short Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases
title_full Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases
title_fullStr Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases
title_full_unstemmed Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases
title_sort Schwannoma of the Upper Extremity: Retrospective Analysis of 17 Cases
author Sá, Ângelo
author_facet Sá, Ângelo
Azevedo, Leandro Nobre
Cunha, Luísa
author_role author
author2 Azevedo, Leandro Nobre
Cunha, Luísa
author2_role author
author
dc.contributor.author.fl_str_mv Sá, Ângelo
Azevedo, Leandro Nobre
Cunha, Luísa
dc.subject.por.fl_str_mv Hand
Neurilemmoma
Soft Tissue Neoplasms
Upper Extremity.
Extremidade Superior
Mão
Neoplasias de Tecidos Moles
Neurilemoma.
topic Hand
Neurilemmoma
Soft Tissue Neoplasms
Upper Extremity.
Extremidade Superior
Mão
Neoplasias de Tecidos Moles
Neurilemoma.
description Introduction: Schwannoma or neurilemmoma is a benign peripheric nerve tumor that usually presents as a slow growing single lesion; it has origin in Schwann cells proliferation. Although it represents a small percentage of the benign tumors of the upper arm, it is the most frequent of neural origin. We present a retrospective study of upper limb schwannomas; our aim is establish the appropriate preoperative approach, to recognise the efficiency of the treatment and the pos-operative follow-up.Material and Methods: Review of 17 patients treated between 2007 and 2014 with upper limb schwannoma and characterization as to age, gender, location in the upper limb, signs and symptoms, pre-operative studies, histologic diagnosis and postoperative surveillance.Results: In four of them the schwannoma was localized on the arm, three on the forearm, four on the wrist and 6 on the hand or fingers. We proceed to careful microsurgical dissection in a bloodless field to optimize the functional final result. The enucleation without fascicular lesion was achieved in 12 patients. In five patients we performed the excision of the fascicles involved by the mass. Nine patients developed paresthesias in the immediate postoperative period, with five of them improving in 12 months. One patient presented motor deficit of the radial nerve with partial recover at 12 monts.Discussion: Schwannomas are rare tumours with well circumscribed morphology. Occasionally it appears in upper limb. The preoperativediagnosis is rarely, so normally the diagnosis is established only after excision and histologic study.Conclusion: Schwannoma should be considered as a diagnostic hypothesis when evaluating subcutaneous nodes associated withneurologic symptoms. It is important to query the presence of paresthesias and perform the Tinel sign, both typical of this condition.Imagiological exams have a scarce contribute in the diagnosis. To improve the final result, the preoperative study must be insightful, being advisable to consider the benefits of the surgery compared to the potential iatrogenic damage to the nerve.
publishDate 2016
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7842
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7843
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7844
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7845
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/7846
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/8034
https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/6906/8703
dc.rights.driver.fl_str_mv Direitos de Autor (c) 2016 Acta Médica Portuguesa
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 29 No. 9 (2016): September; 519-524
Acta Médica Portuguesa; Vol. 29 N.º 9 (2016): Setembro; 519-524
1646-0758
0870-399X
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