Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene
Autor(a) principal: | |
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Data de Publicação: | 2022 |
Outros Autores: | , , , , , |
Tipo de documento: | Artigo |
Idioma: | eng |
Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
Texto Completo: | http://hdl.handle.net/10400.14/39181 |
Resumo: | The present study aimed to test, in vitro, the antimicrobial activity against Candida albicans and Streptococcus mutans and the surface roughness of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene. A 3D-printed polymethylmethacrylate dental resin was reinforced with four different concentrations of graphene: 0.01, 0.1, 0.25 and 0.5 wt%. Neat resin was used as a control. The specimens were printed in a liquid crystal display printer. Disc specimens were used in antimicrobial evaluation, and bar-shaped specimens were used to measure surface roughness. The study of antimicrobial activity included the inhibition of the growth of C. albicans and S. mutans and their adhesion to the resin’s surface. Surface roughness increased with the increase in the graphene concentration. The growth inhibition of C. albicans was observed in the different concentrations of graphene after 24 h, with no recovery after 48 h. The specimens doped with graphene were capable of inactivating S. mutans after 48 h. The surface-adhesion studies showed that the density of microbial biofilms decreases in the case of specimens doped with graphene. Graphene, despite increasing the resin’s surface roughness, was effective in inhibiting the growth and the adhesion to the resin’s surface of the main inducers of prosthetic stomatitis. |
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Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
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Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphenePolymethyl methacrylateGrapheneCandida albicansStreptococcus mutansDenture stomatitis3D printingThe present study aimed to test, in vitro, the antimicrobial activity against Candida albicans and Streptococcus mutans and the surface roughness of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene. A 3D-printed polymethylmethacrylate dental resin was reinforced with four different concentrations of graphene: 0.01, 0.1, 0.25 and 0.5 wt%. Neat resin was used as a control. The specimens were printed in a liquid crystal display printer. Disc specimens were used in antimicrobial evaluation, and bar-shaped specimens were used to measure surface roughness. The study of antimicrobial activity included the inhibition of the growth of C. albicans and S. mutans and their adhesion to the resin’s surface. Surface roughness increased with the increase in the graphene concentration. The growth inhibition of C. albicans was observed in the different concentrations of graphene after 24 h, with no recovery after 48 h. The specimens doped with graphene were capable of inactivating S. mutans after 48 h. The surface-adhesion studies showed that the density of microbial biofilms decreases in the case of specimens doped with graphene. Graphene, despite increasing the resin’s surface roughness, was effective in inhibiting the growth and the adhesion to the resin’s surface of the main inducers of prosthetic stomatitis.Veritati - Repositório Institucional da Universidade Católica PortuguesaSalgado, HelenaGomes, Ana T. P. C.Duarte, Ana S.Ferreira, José M. F.Fernandes, CarlosFigueiral, Maria HelenaMesquita, Pedro2022-10-26T08:19:47Z2022-10-172022-10-17T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.14/39181eng2227-905910.3390/biomedicines1010260785140651761PMC959947336289869000872187100001info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-01-16T01:45:01Zoai:repositorio.ucp.pt:10400.14/39181Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:32:01.618971Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
dc.title.none.fl_str_mv |
Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene |
title |
Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene |
spellingShingle |
Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene Salgado, Helena Polymethyl methacrylate Graphene Candida albicans Streptococcus mutans Denture stomatitis 3D printing |
title_short |
Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene |
title_full |
Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene |
title_fullStr |
Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene |
title_full_unstemmed |
Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene |
title_sort |
Antimicrobial activity of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene |
author |
Salgado, Helena |
author_facet |
Salgado, Helena Gomes, Ana T. P. C. Duarte, Ana S. Ferreira, José M. F. Fernandes, Carlos Figueiral, Maria Helena Mesquita, Pedro |
author_role |
author |
author2 |
Gomes, Ana T. P. C. Duarte, Ana S. Ferreira, José M. F. Fernandes, Carlos Figueiral, Maria Helena Mesquita, Pedro |
author2_role |
author author author author author author |
dc.contributor.none.fl_str_mv |
Veritati - Repositório Institucional da Universidade Católica Portuguesa |
dc.contributor.author.fl_str_mv |
Salgado, Helena Gomes, Ana T. P. C. Duarte, Ana S. Ferreira, José M. F. Fernandes, Carlos Figueiral, Maria Helena Mesquita, Pedro |
dc.subject.por.fl_str_mv |
Polymethyl methacrylate Graphene Candida albicans Streptococcus mutans Denture stomatitis 3D printing |
topic |
Polymethyl methacrylate Graphene Candida albicans Streptococcus mutans Denture stomatitis 3D printing |
description |
The present study aimed to test, in vitro, the antimicrobial activity against Candida albicans and Streptococcus mutans and the surface roughness of a 3D-printed polymethylmethacrylate dental resin enhanced with graphene. A 3D-printed polymethylmethacrylate dental resin was reinforced with four different concentrations of graphene: 0.01, 0.1, 0.25 and 0.5 wt%. Neat resin was used as a control. The specimens were printed in a liquid crystal display printer. Disc specimens were used in antimicrobial evaluation, and bar-shaped specimens were used to measure surface roughness. The study of antimicrobial activity included the inhibition of the growth of C. albicans and S. mutans and their adhesion to the resin’s surface. Surface roughness increased with the increase in the graphene concentration. The growth inhibition of C. albicans was observed in the different concentrations of graphene after 24 h, with no recovery after 48 h. The specimens doped with graphene were capable of inactivating S. mutans after 48 h. The surface-adhesion studies showed that the density of microbial biofilms decreases in the case of specimens doped with graphene. Graphene, despite increasing the resin’s surface roughness, was effective in inhibiting the growth and the adhesion to the resin’s surface of the main inducers of prosthetic stomatitis. |
publishDate |
2022 |
dc.date.none.fl_str_mv |
2022-10-26T08:19:47Z 2022-10-17 2022-10-17T00:00:00Z |
dc.type.status.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.driver.fl_str_mv |
info:eu-repo/semantics/article |
format |
article |
status_str |
publishedVersion |
dc.identifier.uri.fl_str_mv |
http://hdl.handle.net/10400.14/39181 |
url |
http://hdl.handle.net/10400.14/39181 |
dc.language.iso.fl_str_mv |
eng |
language |
eng |
dc.relation.none.fl_str_mv |
2227-9059 10.3390/biomedicines10102607 85140651761 PMC9599473 36289869 000872187100001 |
dc.rights.driver.fl_str_mv |
info:eu-repo/semantics/openAccess |
eu_rights_str_mv |
openAccess |
dc.format.none.fl_str_mv |
application/pdf |
dc.source.none.fl_str_mv |
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
instname_str |
Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
instacron_str |
RCAAP |
institution |
RCAAP |
reponame_str |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
collection |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
repository.name.fl_str_mv |
Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação |
repository.mail.fl_str_mv |
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1799132044498829312 |