Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard Syndrome

Detalhes bibliográficos
Autor(a) principal: Silva, Cristiana
Data de Publicação: 2024
Outros Autores: Lima, Ana Cláudia, Santana, Isabel, Batista, Sonia
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://doi.org/10.46531/sinapse/CC/210074/2022
Resumo: Myelitis is a rare neurological complication of COVID-19. We will describe a patient with post-COVID-19 myelitis manifesting as partial Brown-Séquard syndrome. A 33-year-old male presented with progressive weakness of the lower limbs, evolving over the previous week. Six weeks before, the patient had had COVID-19, from which he had already recovered. Neurological examination revealed right lower limb weakness and reduced pain sensation on the left lower limb, with a T5-T6 sensory level. Thoracic magnetic resonance imaging (MRI) revealed a right intra-medullary lesion spanning from T3 to T4 with T2 signal hyperintensity. Cerebrospinal fluid study was normal, and SARS-CoV-2 was undetected. After excluding active infection, the patient received methylprednisolone and the symptoms improved. One month later, the neurological exam was considered normal and there was a significant lesion reduction on MRI. SARS-CoV-2 infection should be considered as a possible aetiology for myelitis in all patients, even in those with mild infection or asymptomatic.
id RCAP_9261e3fcf7cb27b9ae8bb199ee14ee46
oai_identifier_str oai:sinapse.pt:article/76
network_acronym_str RCAP
network_name_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository_id_str 7160
spelling Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard SyndromeMielite Pós-COVID-19 Apresentando-se como Síndrome de Brown-Séquard ParcialCOVID-19/complicationsMyelitis, TransverseSARS-CoV-2COVID-19/complicaçõesMielite TransversaSARS-CoV-2Myelitis is a rare neurological complication of COVID-19. We will describe a patient with post-COVID-19 myelitis manifesting as partial Brown-Séquard syndrome. A 33-year-old male presented with progressive weakness of the lower limbs, evolving over the previous week. Six weeks before, the patient had had COVID-19, from which he had already recovered. Neurological examination revealed right lower limb weakness and reduced pain sensation on the left lower limb, with a T5-T6 sensory level. Thoracic magnetic resonance imaging (MRI) revealed a right intra-medullary lesion spanning from T3 to T4 with T2 signal hyperintensity. Cerebrospinal fluid study was normal, and SARS-CoV-2 was undetected. After excluding active infection, the patient received methylprednisolone and the symptoms improved. One month later, the neurological exam was considered normal and there was a significant lesion reduction on MRI. SARS-CoV-2 infection should be considered as a possible aetiology for myelitis in all patients, even in those with mild infection or asymptomatic.A mielite é uma complicação neurológica rara da COVID-19. Descrevemos o caso de um doente com mielite pós-COVID-19, que se apresenta como síndrome de Brown-Séquard parcial. Um doente do sexo masculino, 33 anos, recorre ao hospital por história de fraqueza progressiva dos membros inferiores com uma semana de evolução. Seis semanas antes, tinha tido COVID-19, entretanto recuperado. Ao exame neurológico, apresentava défice de força do membro inferior direito e hipostesia à esquerda, com nível sensitivo T5-T6. A ressonância magnética (RM) torácica revelou lesão intramedular hiperintensa direita em T3-T4. O estudo do líquido cefalorraquidiano foi normal e não foi detetado SARS-CoV-2. Após exclusão de infeção ativa, o doente iniciou metilprednisolona, observando-se melhoria clínica. Um mês depois, o exame neurológico era normal e houve marcada redução da lesão na RM. A infeção por SARS-CoV-2 deve ser considerada como uma possível etiologia de mielite em todos os doentes, mesmo naqueles com infeção ligeira ou assintomáticos.Portuguese Society of Neurology2024-04-20info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://doi.org/10.46531/sinapse/CC/210074/2022https://doi.org/10.46531/sinapse/CC/210074/2022Sinapse; Vol. 22 No. 1 (2022): January - March; 34-37Sinapse; Vol. 22 N.º 1 (2022): Janeiro - Março; 34-372184-42401645-281Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPenghttps://sinapse.pt/index.php/journal/article/view/76https://sinapse.pt/index.php/journal/article/view/76/72Copyright (c) 2024 Cristiana Silva, Ana Cláudia Lima, Isabel Santana, Sonia Batistainfo:eu-repo/semantics/openAccessSilva, CristianaLima, Ana CláudiaSantana, IsabelBatista, Sonia2024-04-30T10:08:50Zoai:sinapse.pt:article/76Portal AgregadorONGhttps://www.rcaap.pt/oai/openairemluisa.alvim@gmail.comopendoar:71602024-04-30T10:08:50Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard Syndrome
Mielite Pós-COVID-19 Apresentando-se como Síndrome de Brown-Séquard Parcial
title Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard Syndrome
spellingShingle Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard Syndrome
Silva, Cristiana
COVID-19/complications
Myelitis, Transverse
SARS-CoV-2
COVID-19/complicações
Mielite Transversa
SARS-CoV-2
title_short Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard Syndrome
title_full Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard Syndrome
title_fullStr Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard Syndrome
title_full_unstemmed Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard Syndrome
title_sort Post-COVID-19 Myelitis Manifesting as Partial Brown-Séquard Syndrome
author Silva, Cristiana
author_facet Silva, Cristiana
Lima, Ana Cláudia
Santana, Isabel
Batista, Sonia
author_role author
author2 Lima, Ana Cláudia
Santana, Isabel
Batista, Sonia
author2_role author
author
author
dc.contributor.author.fl_str_mv Silva, Cristiana
Lima, Ana Cláudia
Santana, Isabel
Batista, Sonia
dc.subject.por.fl_str_mv COVID-19/complications
Myelitis, Transverse
SARS-CoV-2
COVID-19/complicações
Mielite Transversa
SARS-CoV-2
topic COVID-19/complications
Myelitis, Transverse
SARS-CoV-2
COVID-19/complicações
Mielite Transversa
SARS-CoV-2
description Myelitis is a rare neurological complication of COVID-19. We will describe a patient with post-COVID-19 myelitis manifesting as partial Brown-Séquard syndrome. A 33-year-old male presented with progressive weakness of the lower limbs, evolving over the previous week. Six weeks before, the patient had had COVID-19, from which he had already recovered. Neurological examination revealed right lower limb weakness and reduced pain sensation on the left lower limb, with a T5-T6 sensory level. Thoracic magnetic resonance imaging (MRI) revealed a right intra-medullary lesion spanning from T3 to T4 with T2 signal hyperintensity. Cerebrospinal fluid study was normal, and SARS-CoV-2 was undetected. After excluding active infection, the patient received methylprednisolone and the symptoms improved. One month later, the neurological exam was considered normal and there was a significant lesion reduction on MRI. SARS-CoV-2 infection should be considered as a possible aetiology for myelitis in all patients, even in those with mild infection or asymptomatic.
publishDate 2024
dc.date.none.fl_str_mv 2024-04-20
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv https://doi.org/10.46531/sinapse/CC/210074/2022
https://doi.org/10.46531/sinapse/CC/210074/2022
url https://doi.org/10.46531/sinapse/CC/210074/2022
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv https://sinapse.pt/index.php/journal/article/view/76
https://sinapse.pt/index.php/journal/article/view/76/72
dc.rights.driver.fl_str_mv Copyright (c) 2024 Cristiana Silva, Ana Cláudia Lima, Isabel Santana, Sonia Batista
info:eu-repo/semantics/openAccess
rights_invalid_str_mv Copyright (c) 2024 Cristiana Silva, Ana Cláudia Lima, Isabel Santana, Sonia Batista
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Portuguese Society of Neurology
publisher.none.fl_str_mv Portuguese Society of Neurology
dc.source.none.fl_str_mv Sinapse; Vol. 22 No. 1 (2022): January - March; 34-37
Sinapse; Vol. 22 N.º 1 (2022): Janeiro - Março; 34-37
2184-4240
1645-281X
reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv mluisa.alvim@gmail.com
_version_ 1817543354780483584