Drug--induced splenomegaly.
| Autor(a) principal: | |
|---|---|
| Data de Publicação: | 2011 |
| Tipo de documento: | Artigo |
| Idioma: | por |
| Título da fonte: | Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) |
| Texto Completo: | https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1570 |
Resumo: | The diagnosis of splenomegaly due to drugs is based on a recent history of exposure to a drug before the spleen enlargement. The purpose of this paper is to review studies of the literature on drugs that may induce to splenomegaly. Drugs may provoke the enlargement of spleen by direct effect in splenic cells or as a side effect of disturbances in other organs, mainly liver and haematoimmunologic system. Some drugs provoke severe haemolysis associated with splenomegaly. Another cause of spleen increasing in size is the venous congestion due to liver disturbance with portal vein occlusion. All these drug side effects are usually transitory and splenomegaly disappears when the medication is discontinued. This is a complex problem that must be better studied to be understood in order to prevent its occurrence and to find the best treatment. |
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Drug--induced splenomegaly.Esplenomegalia induzida por drogas.The diagnosis of splenomegaly due to drugs is based on a recent history of exposure to a drug before the spleen enlargement. The purpose of this paper is to review studies of the literature on drugs that may induce to splenomegaly. Drugs may provoke the enlargement of spleen by direct effect in splenic cells or as a side effect of disturbances in other organs, mainly liver and haematoimmunologic system. Some drugs provoke severe haemolysis associated with splenomegaly. Another cause of spleen increasing in size is the venous congestion due to liver disturbance with portal vein occlusion. All these drug side effects are usually transitory and splenomegaly disappears when the medication is discontinued. This is a complex problem that must be better studied to be understood in order to prevent its occurrence and to find the best treatment.The diagnosis of splenomegaly due to drugs is based on a recent history of exposure to a drug before the spleen enlargement. The purpose of this paper is to review studies of the literature on drugs that may induce to splenomegaly. Drugs may provoke the enlargement of spleen by direct effect in splenic cells or as a side effect of disturbances in other organs, mainly liver and haematoimmunologic system. Some drugs provoke severe haemolysis associated with splenomegaly. Another cause of spleen increasing in size is the venous congestion due to liver disturbance with portal vein occlusion. All these drug side effects are usually transitory and splenomegaly disappears when the medication is discontinued. This is a complex problem that must be better studied to be understood in order to prevent its occurrence and to find the best treatment.Ordem dos Médicos2011-12-31info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1570oai:ojs.www.actamedicaportuguesa.com:article/1570Acta Médica Portuguesa; Vol. 24 (2011): Suplemento 4; 977-82Acta Médica Portuguesa; Vol. 24 (2011): Suplemento 4; 977-821646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1570https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1570/1154Petroianu, Andyinfo:eu-repo/semantics/openAccess2022-12-20T10:58:10Zoai:ojs.www.actamedicaportuguesa.com:article/1570Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:17:14.568857Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse |
| dc.title.none.fl_str_mv |
Drug--induced splenomegaly. Esplenomegalia induzida por drogas. |
| title |
Drug--induced splenomegaly. |
| spellingShingle |
Drug--induced splenomegaly. Petroianu, Andy |
| title_short |
Drug--induced splenomegaly. |
| title_full |
Drug--induced splenomegaly. |
| title_fullStr |
Drug--induced splenomegaly. |
| title_full_unstemmed |
Drug--induced splenomegaly. |
| title_sort |
Drug--induced splenomegaly. |
| author |
Petroianu, Andy |
| author_facet |
Petroianu, Andy |
| author_role |
author |
| dc.contributor.author.fl_str_mv |
Petroianu, Andy |
| description |
The diagnosis of splenomegaly due to drugs is based on a recent history of exposure to a drug before the spleen enlargement. The purpose of this paper is to review studies of the literature on drugs that may induce to splenomegaly. Drugs may provoke the enlargement of spleen by direct effect in splenic cells or as a side effect of disturbances in other organs, mainly liver and haematoimmunologic system. Some drugs provoke severe haemolysis associated with splenomegaly. Another cause of spleen increasing in size is the venous congestion due to liver disturbance with portal vein occlusion. All these drug side effects are usually transitory and splenomegaly disappears when the medication is discontinued. This is a complex problem that must be better studied to be understood in order to prevent its occurrence and to find the best treatment. |
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2011 |
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2011-12-31 |
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info:eu-repo/semantics/publishedVersion |
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info:eu-repo/semantics/article |
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article |
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publishedVersion |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1570 oai:ojs.www.actamedicaportuguesa.com:article/1570 |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1570 |
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por |
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por |
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https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1570 https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/1570/1154 |
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Ordem dos Médicos |
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Ordem dos Médicos |
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Acta Médica Portuguesa; Vol. 24 (2011): Suplemento 4; 977-82 Acta Médica Portuguesa; Vol. 24 (2011): Suplemento 4; 977-82 1646-0758 0870-399X reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação instacron:RCAAP |
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