Lanthanide-Based Organic Salts

Detalhes bibliográficos
Autor(a) principal: Forte, Andreia
Data de Publicação: 2023
Outros Autores: Gago, Sandra, Alves, Celso, Silva, Joana, Alves, Joana, Pedrosa, Rui, Laia, César A. T., Marrucho, Isabel M., Branco, Luís C.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10362/163973
Resumo: Funding Information: This work was supported by Fundação para a Ciência e a Tecnologia through projects (PEst-C/LA0006/2013, PTCD/CTM-NAN/120658/2010, two contracts under Investigador FCT (L. C. Branco and I. M. Marrucho), a doctoral fellowship Andreia Forte (PD/BD/109625/2015), and by the Portuguese Foundation for Science and Technology (FCT) through the strategic project UID/MAR/04292/2020 granted to MARE—Marine and Environmental Sciences Centre and Solchemar company. Publisher Copyright: © 2023 by the authors.
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spelling Lanthanide-Based Organic SaltsSynthesis, Characterization, and Cytotoxicity Studiescytotoxicitygadolinium saltsmagnetic organic saltsMRI contrast agentsterbium saltsAnalytical ChemistryChemistry (miscellaneous)Molecular MedicinePharmaceutical ScienceDrug DiscoveryPhysical and Theoretical ChemistryOrganic ChemistryFunding Information: This work was supported by Fundação para a Ciência e a Tecnologia through projects (PEst-C/LA0006/2013, PTCD/CTM-NAN/120658/2010, two contracts under Investigador FCT (L. C. Branco and I. M. Marrucho), a doctoral fellowship Andreia Forte (PD/BD/109625/2015), and by the Portuguese Foundation for Science and Technology (FCT) through the strategic project UID/MAR/04292/2020 granted to MARE—Marine and Environmental Sciences Centre and Solchemar company. Publisher Copyright: © 2023 by the authors.The formulation of magnetic ionic liquids (MILs) or organic salts based on lanthanides as anions has been explored. In this work, a set of choline-family-based salts, and two other, different cation families, were combined with Gadolinium(III) and Terbium(III) anions. Synthetic methodologies were previously optimized, and all organic salts were obtained as solids with melting temperatures higher than 100 °C. The magnetic moments obtained for the Gd(III) salts were, as expected, smaller than those obtained for the Tb(III)-based compounds. The values for Gd(III) and Tb(III) magnetic salts are in the range of 6.55–7.30 MB and 8.22–9.34 MB, respectively. It is important to note a correlation between the magnetic moments obtained for lanthanides, and the structural features of the cation. The cytotoxicity of lanthanide-based salts was also evaluated using 3T3, 293T, Caco2, and HepG2 cells, and it was revealed that most of the prepared compounds are not toxic.Instituto de Tecnologia Química e Biológica António Xavier (ITQB)LAQV@REQUIMTERUNForte, AndreiaGago, SandraAlves, CelsoSilva, JoanaAlves, JoanaPedrosa, RuiLaia, César A. T.Marrucho, Isabel M.Branco, Luís C.2024-02-22T23:51:58Z2023-10-182023-10-18T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/article13application/pdfhttp://hdl.handle.net/10362/163973eng1420-3049PURE: 83888255https://doi.org/10.3390/molecules28207152info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2024-03-11T05:49:57Zoai:run.unl.pt:10362/163973Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T03:59:57.996416Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Lanthanide-Based Organic Salts
Synthesis, Characterization, and Cytotoxicity Studies
title Lanthanide-Based Organic Salts
spellingShingle Lanthanide-Based Organic Salts
Forte, Andreia
cytotoxicity
gadolinium salts
magnetic organic salts
MRI contrast agents
terbium salts
Analytical Chemistry
Chemistry (miscellaneous)
Molecular Medicine
Pharmaceutical Science
Drug Discovery
Physical and Theoretical Chemistry
Organic Chemistry
title_short Lanthanide-Based Organic Salts
title_full Lanthanide-Based Organic Salts
title_fullStr Lanthanide-Based Organic Salts
title_full_unstemmed Lanthanide-Based Organic Salts
title_sort Lanthanide-Based Organic Salts
author Forte, Andreia
author_facet Forte, Andreia
Gago, Sandra
Alves, Celso
Silva, Joana
Alves, Joana
Pedrosa, Rui
Laia, César A. T.
Marrucho, Isabel M.
Branco, Luís C.
author_role author
author2 Gago, Sandra
Alves, Celso
Silva, Joana
Alves, Joana
Pedrosa, Rui
Laia, César A. T.
Marrucho, Isabel M.
Branco, Luís C.
author2_role author
author
author
author
author
author
author
author
dc.contributor.none.fl_str_mv Instituto de Tecnologia Química e Biológica António Xavier (ITQB)
LAQV@REQUIMTE
RUN
dc.contributor.author.fl_str_mv Forte, Andreia
Gago, Sandra
Alves, Celso
Silva, Joana
Alves, Joana
Pedrosa, Rui
Laia, César A. T.
Marrucho, Isabel M.
Branco, Luís C.
dc.subject.por.fl_str_mv cytotoxicity
gadolinium salts
magnetic organic salts
MRI contrast agents
terbium salts
Analytical Chemistry
Chemistry (miscellaneous)
Molecular Medicine
Pharmaceutical Science
Drug Discovery
Physical and Theoretical Chemistry
Organic Chemistry
topic cytotoxicity
gadolinium salts
magnetic organic salts
MRI contrast agents
terbium salts
Analytical Chemistry
Chemistry (miscellaneous)
Molecular Medicine
Pharmaceutical Science
Drug Discovery
Physical and Theoretical Chemistry
Organic Chemistry
description Funding Information: This work was supported by Fundação para a Ciência e a Tecnologia through projects (PEst-C/LA0006/2013, PTCD/CTM-NAN/120658/2010, two contracts under Investigador FCT (L. C. Branco and I. M. Marrucho), a doctoral fellowship Andreia Forte (PD/BD/109625/2015), and by the Portuguese Foundation for Science and Technology (FCT) through the strategic project UID/MAR/04292/2020 granted to MARE—Marine and Environmental Sciences Centre and Solchemar company. Publisher Copyright: © 2023 by the authors.
publishDate 2023
dc.date.none.fl_str_mv 2023-10-18
2023-10-18T00:00:00Z
2024-02-22T23:51:58Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10362/163973
url http://hdl.handle.net/10362/163973
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 1420-3049
PURE: 83888255
https://doi.org/10.3390/molecules28207152
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv 13
application/pdf
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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