Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathy

Detalhes bibliográficos
Autor(a) principal: Furtado, AL
Data de Publicação: 2000
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.4/396
Resumo: Transplantation of livers from patients with familial amyloidotic polyneuropathy undergoing orthotopic liver transplantation is based on the normal functions of these livers, except for the production of an abnormal protein that causes the disease, which takes more than 20 years to become clinically apparent. Given the shortage of cadaver grafts, domino liver transplantation has the potential to increase the offer to some selected patients. The known experience amounts to little more than 80 cases. Domino liver transplantation has been a safe procedure with all the advantages of living donor grafts. So far, the disease has not shown up in any recipient, including the longest surviving patient (4 years). Particularly in countries where the disease is common, the potential to increase graft offer may be significantly augmented through cooperation between centers and better exploitation of technical possibilities. The combination of split and domino has been reported six times and may provide three to six transplants from only one cadaver graft
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spelling Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathyPolineuropatia Amiloidótica FamiliarTransplantação de FígadoTransplantation of livers from patients with familial amyloidotic polyneuropathy undergoing orthotopic liver transplantation is based on the normal functions of these livers, except for the production of an abnormal protein that causes the disease, which takes more than 20 years to become clinically apparent. Given the shortage of cadaver grafts, domino liver transplantation has the potential to increase the offer to some selected patients. The known experience amounts to little more than 80 cases. Domino liver transplantation has been a safe procedure with all the advantages of living donor grafts. So far, the disease has not shown up in any recipient, including the longest surviving patient (4 years). Particularly in countries where the disease is common, the potential to increase graft offer may be significantly augmented through cooperation between centers and better exploitation of technical possibilities. The combination of split and domino has been reported six times and may provide three to six transplants from only one cadaver graftRIHUCFurtado, AL2008-12-30T12:57:34Z20002000-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.4/396engCurr Opin Organ Transplant. 2000;5(2):69-73info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-11T14:21:33Zoai:rihuc.huc.min-saude.pt:10400.4/396Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T18:03:12.002613Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathy
title Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathy
spellingShingle Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathy
Furtado, AL
Polineuropatia Amiloidótica Familiar
Transplantação de Fígado
title_short Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathy
title_full Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathy
title_fullStr Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathy
title_full_unstemmed Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathy
title_sort Domino liver transplantation using livers from patients with familial amyloidotic polyneuropathy
author Furtado, AL
author_facet Furtado, AL
author_role author
dc.contributor.none.fl_str_mv RIHUC
dc.contributor.author.fl_str_mv Furtado, AL
dc.subject.por.fl_str_mv Polineuropatia Amiloidótica Familiar
Transplantação de Fígado
topic Polineuropatia Amiloidótica Familiar
Transplantação de Fígado
description Transplantation of livers from patients with familial amyloidotic polyneuropathy undergoing orthotopic liver transplantation is based on the normal functions of these livers, except for the production of an abnormal protein that causes the disease, which takes more than 20 years to become clinically apparent. Given the shortage of cadaver grafts, domino liver transplantation has the potential to increase the offer to some selected patients. The known experience amounts to little more than 80 cases. Domino liver transplantation has been a safe procedure with all the advantages of living donor grafts. So far, the disease has not shown up in any recipient, including the longest surviving patient (4 years). Particularly in countries where the disease is common, the potential to increase graft offer may be significantly augmented through cooperation between centers and better exploitation of technical possibilities. The combination of split and domino has been reported six times and may provide three to six transplants from only one cadaver graft
publishDate 2000
dc.date.none.fl_str_mv 2000
2000-01-01T00:00:00Z
2008-12-30T12:57:34Z
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dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.4/396
url http://hdl.handle.net/10400.4/396
dc.language.iso.fl_str_mv eng
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dc.relation.none.fl_str_mv Curr Opin Organ Transplant. 2000;5(2):69-73
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