Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service Experience

Detalhes bibliográficos
Autor(a) principal: Soares do Brito, Joaquim
Data de Publicação: 2013
Outros Autores: Batista, Nuno, Tirado, António, Fernandes, Pedro
Tipo de documento: Artigo
Idioma: por
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207
Resumo: Introduction: Tuberculosis is responsible for more than 40% of spine infections. While tuberculostatic chemotherapy remains the goldstandard treatment, surgical intervention is necessary only in specific cases. This paper reports the results of 33 patients with spine tuberculosis operated in our department in the last 15 years.Objective: Evaluate retrospectively patients with spine tuberculosis operated in the last 15 years - from 1996 to 2011; evaluate the surgical options, infection resolution results, deformity correction, functional results and outcome in cases of neurological injury.Material and Methods: Analysis of clinical and radiological assessments of patients diagnosed with spine tuberculosis and operated between 1996 and 2011. In this period 33 patients were operated with average age of 46.7 years; 17 patients had thoracic infection, 11 patients lumbar infection and 5 thoraco-lumbar infection. Paravertebral abscess was identified in 26 cases with intracanal extension in 16 patients. Nine patients had neurological injury. The anterior surgical approach was used in seven cases, the posterior approach in 11 and anterior-posterior approach was preferred in 15 occasions. Antituberculous chemotherapy was maintained on average for 14months, with mean follow up of 24 months.Results: The infection was eradicated in all patients. Bone fusion was found in average at 10.6 months follow-up. The anterior approach did not produce correction of the initial deformity, while the posterior approach allowed average correction of 12.7° and the anterior-posterior approach a mean correction of 8.7°. Five patients with neurological injury experienced improvement of 2 or 3 levels in ASIA score. We also report complications in two cases where superficial wound infection was diagnosed.Discussion and Conclusion: Treatment with antituberculosis drugs is the first-line therapy in the treatment of tuberculous spondylodiscitis, while surgical treatment has specific indications. The surgical option, when indicated, allows deformity correction and bone fusion. The anterior-posterior or only posterior surgical approach is preferred in this context. The complication rate was not significant despite the introduction of osteosynthesis hardware.
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spelling Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service ExperienceTratamento Cirúrgico da Espondilodiscite Tuberculosa: Experiência de um Serviço de OrtopediaIntroduction: Tuberculosis is responsible for more than 40% of spine infections. While tuberculostatic chemotherapy remains the goldstandard treatment, surgical intervention is necessary only in specific cases. This paper reports the results of 33 patients with spine tuberculosis operated in our department in the last 15 years.Objective: Evaluate retrospectively patients with spine tuberculosis operated in the last 15 years - from 1996 to 2011; evaluate the surgical options, infection resolution results, deformity correction, functional results and outcome in cases of neurological injury.Material and Methods: Analysis of clinical and radiological assessments of patients diagnosed with spine tuberculosis and operated between 1996 and 2011. In this period 33 patients were operated with average age of 46.7 years; 17 patients had thoracic infection, 11 patients lumbar infection and 5 thoraco-lumbar infection. Paravertebral abscess was identified in 26 cases with intracanal extension in 16 patients. Nine patients had neurological injury. The anterior surgical approach was used in seven cases, the posterior approach in 11 and anterior-posterior approach was preferred in 15 occasions. Antituberculous chemotherapy was maintained on average for 14months, with mean follow up of 24 months.Results: The infection was eradicated in all patients. Bone fusion was found in average at 10.6 months follow-up. The anterior approach did not produce correction of the initial deformity, while the posterior approach allowed average correction of 12.7° and the anterior-posterior approach a mean correction of 8.7°. Five patients with neurological injury experienced improvement of 2 or 3 levels in ASIA score. We also report complications in two cases where superficial wound infection was diagnosed.Discussion and Conclusion: Treatment with antituberculosis drugs is the first-line therapy in the treatment of tuberculous spondylodiscitis, while surgical treatment has specific indications. The surgical option, when indicated, allows deformity correction and bone fusion. The anterior-posterior or only posterior surgical approach is preferred in this context. The complication rate was not significant despite the introduction of osteosynthesis hardware.Introdução: A espondilodiscite de etiologia tuberculosa é responsável por mais de 40% do universo destas infeções. Enquanto a quimioterapia tuberculostática se mantém como gold-standard da terapêutica desta patologia, o tratamento cirúrgico tem lugar em situações muito específicas. Neste trabalho apresentam-se os resultados de 33 doentes com espondilodiscite tuberculosa operados no nosso serviço durante os últimos 15 anos.Objetivo: Avaliar retrospetivamente doentes com diagnóstico de espondilodiscite tuberculosa operados num período de 15 anos(1996 a 2011); avaliar opções cirúrgicas tomadas e respetivos resultados relativamente à resolução da infeção, controlo da deformidade e evolução da lesão neurológica.Material e Métodos: Análise retrospetiva dos processos clínicos e avaliações imagiológicas de doentes com diagnóstico de espondilodiscite tuberculosa operados entre 1996 e 2011. Foram identificados 33 doentes com idade média de 46,7 anos; 17 doentes apresentavam infeção torácica, 11 lombar e cinco toraco-lombar. O abcesso paravertebral foi identificado em 26 dos casos estudados, existindo extensão intracanalar em 16 doentes. Nove dos doentes avaliados apresentavam lesão neurológica. A abordagem cirúrgica por via anterior foi utilizada em sete casos, a via posterior em 11 e a abordagem combinada foi a preferida em 15 ocasiões. A quimioterapia antibacilar foi mantida em média por 14 meses, com seguimento médio de 24 meses.Resultados: Verificámos cura da infeção em todos os doentes, sendo documentados critérios de fusão óssea, em média, 10,6 meses pós-cirurgia. A abordagem anterior isolada não permitiu obter correção da deformidade inicial, enquanto a via posterior permitiu uma correção média de 12,7º e a via combinada uma correção média de 8,7º. Cinco dos doentes com lesão neurológica melhoraram 2 a 3 níveis na escala ASIA durante o seguimento pós-operatório. Como complicações referem-se 2 casos de infeção superficial da ferida operatória.Discussão e Conclusão: A terapêutica com antibacilares constitui a terapêutica de primeira linha no tratamento da espondilodiscite tuberculosa, existindo indicações específicas para realização de cirurgia. A intervenção cirúrgica, quando indicada, permite corrigir a deformidade assim como a fusão óssea, sendo preferencialmente realizada por via combinada ou posterior. A taxa de complicações foi pouco significativa apesar da introdução de material de osteossíntese.Ordem dos Médicos2013-08-30info:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfapplication/octet-streamapplication/octet-streamapplication/octet-streamapplication/octet-streamapplication/octet-streamimage/jpegimage/jpegimage/jpegimage/jpegimage/jpeghttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207oai:ojs.www.actamedicaportuguesa.com:article/207Acta Médica Portuguesa; Vol. 26 No. 4 (2013): July-August; 349-356Acta Médica Portuguesa; Vol. 26 N.º 4 (2013): Julho-Agosto; 349-3561646-07580870-399Xreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAPporhttps://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/3707https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6796https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6797https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6798https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6799https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6800https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6890https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6891https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6892https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6893https://www.actamedicaportuguesa.com/revista/index.php/amp/article/view/207/6894Soares do Brito, JoaquimBatista, NunoTirado, AntónioFernandes, Pedroinfo:eu-repo/semantics/openAccess2022-12-20T10:55:52Zoai:ojs.www.actamedicaportuguesa.com:article/207Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T16:16:23.445007Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service Experience
Tratamento Cirúrgico da Espondilodiscite Tuberculosa: Experiência de um Serviço de Ortopedia
title Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service Experience
spellingShingle Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service Experience
Soares do Brito, Joaquim
title_short Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service Experience
title_full Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service Experience
title_fullStr Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service Experience
title_full_unstemmed Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service Experience
title_sort Surgical Treatment of Spinal Tuberculosis: An Orthopedic Service Experience
author Soares do Brito, Joaquim
author_facet Soares do Brito, Joaquim
Batista, Nuno
Tirado, António
Fernandes, Pedro
author_role author
author2 Batista, Nuno
Tirado, António
Fernandes, Pedro
author2_role author
author
author
dc.contributor.author.fl_str_mv Soares do Brito, Joaquim
Batista, Nuno
Tirado, António
Fernandes, Pedro
description Introduction: Tuberculosis is responsible for more than 40% of spine infections. While tuberculostatic chemotherapy remains the goldstandard treatment, surgical intervention is necessary only in specific cases. This paper reports the results of 33 patients with spine tuberculosis operated in our department in the last 15 years.Objective: Evaluate retrospectively patients with spine tuberculosis operated in the last 15 years - from 1996 to 2011; evaluate the surgical options, infection resolution results, deformity correction, functional results and outcome in cases of neurological injury.Material and Methods: Analysis of clinical and radiological assessments of patients diagnosed with spine tuberculosis and operated between 1996 and 2011. In this period 33 patients were operated with average age of 46.7 years; 17 patients had thoracic infection, 11 patients lumbar infection and 5 thoraco-lumbar infection. Paravertebral abscess was identified in 26 cases with intracanal extension in 16 patients. Nine patients had neurological injury. The anterior surgical approach was used in seven cases, the posterior approach in 11 and anterior-posterior approach was preferred in 15 occasions. Antituberculous chemotherapy was maintained on average for 14months, with mean follow up of 24 months.Results: The infection was eradicated in all patients. Bone fusion was found in average at 10.6 months follow-up. The anterior approach did not produce correction of the initial deformity, while the posterior approach allowed average correction of 12.7° and the anterior-posterior approach a mean correction of 8.7°. Five patients with neurological injury experienced improvement of 2 or 3 levels in ASIA score. We also report complications in two cases where superficial wound infection was diagnosed.Discussion and Conclusion: Treatment with antituberculosis drugs is the first-line therapy in the treatment of tuberculous spondylodiscitis, while surgical treatment has specific indications. The surgical option, when indicated, allows deformity correction and bone fusion. The anterior-posterior or only posterior surgical approach is preferred in this context. The complication rate was not significant despite the introduction of osteosynthesis hardware.
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dc.publisher.none.fl_str_mv Ordem dos Médicos
publisher.none.fl_str_mv Ordem dos Médicos
dc.source.none.fl_str_mv Acta Médica Portuguesa; Vol. 26 No. 4 (2013): July-August; 349-356
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