Hyaluronic acid - Based wound dressings: A review

Detalhes bibliográficos
Autor(a) principal: Graça, Mariana F. P.
Data de Publicação: 2020
Outros Autores: Miguel, Sónia P., Cabral, Cátia S. D., Correia, I.J.
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/10400.6/10286
Resumo: Hyaluronic acid (HA), a non-sulfated glycosaminoglycan (GAG), is a major component of skin extracellular matrix (ECM) and it is involved in the inflammatory response, angiogenesis, and tissue regeneration process. Due to the intrinsic properties of HA (such as biocompatibility, biodegradability and hydrophilic character), it has been used to produce different wound dressings, namely sponges, films, hydrogels, and electrospun membranes. Herein, an overview of the different HA-based wound dressings that have been produced so far is provided as well as the future directions regarding the strategies aimed to improve the mechanical stability of HA-based wound dressings, along with the incorporation of biomolecules intended to ameliorate their biological performance during the healing process.
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spelling Hyaluronic acid - Based wound dressings: A reviewHyaluronic acidWound dressingWound healingHyaluronic acid (HA), a non-sulfated glycosaminoglycan (GAG), is a major component of skin extracellular matrix (ECM) and it is involved in the inflammatory response, angiogenesis, and tissue regeneration process. Due to the intrinsic properties of HA (such as biocompatibility, biodegradability and hydrophilic character), it has been used to produce different wound dressings, namely sponges, films, hydrogels, and electrospun membranes. Herein, an overview of the different HA-based wound dressings that have been produced so far is provided as well as the future directions regarding the strategies aimed to improve the mechanical stability of HA-based wound dressings, along with the incorporation of biomolecules intended to ameliorate their biological performance during the healing process.The funding from CENTRO-01-0145-FEDER-028989 and POCI-01-0145-FEDER-031462 is also acknowledged. Cátia S. D. Cabral acknowledge funding from the grant UBI-Santander/Totta.ElsevieruBibliorumGraça, Mariana F. P.Miguel, Sónia P.Cabral, Cátia S. D.Correia, I.J.2022-05-10T00:30:18Z2020-04-272020-04-27T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/10400.6/10286eng10.1016/j.carbpol.2020.116364info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-12-15T09:51:50Zoai:ubibliorum.ubi.pt:10400.6/10286Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:50:17.212423Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Hyaluronic acid - Based wound dressings: A review
title Hyaluronic acid - Based wound dressings: A review
spellingShingle Hyaluronic acid - Based wound dressings: A review
Graça, Mariana F. P.
Hyaluronic acid
Wound dressing
Wound healing
title_short Hyaluronic acid - Based wound dressings: A review
title_full Hyaluronic acid - Based wound dressings: A review
title_fullStr Hyaluronic acid - Based wound dressings: A review
title_full_unstemmed Hyaluronic acid - Based wound dressings: A review
title_sort Hyaluronic acid - Based wound dressings: A review
author Graça, Mariana F. P.
author_facet Graça, Mariana F. P.
Miguel, Sónia P.
Cabral, Cátia S. D.
Correia, I.J.
author_role author
author2 Miguel, Sónia P.
Cabral, Cátia S. D.
Correia, I.J.
author2_role author
author
author
dc.contributor.none.fl_str_mv uBibliorum
dc.contributor.author.fl_str_mv Graça, Mariana F. P.
Miguel, Sónia P.
Cabral, Cátia S. D.
Correia, I.J.
dc.subject.por.fl_str_mv Hyaluronic acid
Wound dressing
Wound healing
topic Hyaluronic acid
Wound dressing
Wound healing
description Hyaluronic acid (HA), a non-sulfated glycosaminoglycan (GAG), is a major component of skin extracellular matrix (ECM) and it is involved in the inflammatory response, angiogenesis, and tissue regeneration process. Due to the intrinsic properties of HA (such as biocompatibility, biodegradability and hydrophilic character), it has been used to produce different wound dressings, namely sponges, films, hydrogels, and electrospun membranes. Herein, an overview of the different HA-based wound dressings that have been produced so far is provided as well as the future directions regarding the strategies aimed to improve the mechanical stability of HA-based wound dressings, along with the incorporation of biomolecules intended to ameliorate their biological performance during the healing process.
publishDate 2020
dc.date.none.fl_str_mv 2020-04-27
2020-04-27T00:00:00Z
2022-05-10T00:30:18Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/10400.6/10286
url http://hdl.handle.net/10400.6/10286
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 10.1016/j.carbpol.2020.116364
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
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reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
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