Normal limits of the electrocardiogram in Angolans

Detalhes bibliográficos
Autor(a) principal: Gonçalves, MAA
Data de Publicação: 2020
Outros Autores: Pedro, JM, Silva, C, Magalhães, P, Brito, M
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: https://hdl.handle.net/10216/143209
Resumo: Introduction. Studies on the normal electrocardiogram limits in African populations are limited, especially in sub-Saharan Africa. There is no literature describing normal ECG limits in Angolans. Objectives. The aim of this study is to establish the normal ECG limits for adult Angolans, without established heart disease, stratified by gender and age. Methods. A cross-sectional study was performed, involving 2179 participants from a population in northern Angola, without established heart disease, aged between 15 and 74 years. A 12‑lead ECG and a rhythm strip were recorded for all participants and analysed and processed by the University of Glasgow software and encoded by the Minnesota Code. The normal range of the electrocardiographic parameters were established as the 2nd and 98th percentiles of the measurement distribution per age group and gender. Mann-Whitney and Kruskal-Wallis tests were used for two independent groups and Bonferroni adjustments were used for multiple testing. GAMLSS models were used to obtain the continuous age-dependent percentile curves. Results. The normal range of the ECG differed between men and women: heart rate 49 to 100 bpm vs. 55 to 108 bpm, P wave duration 81 to 130 ms vs. 84 to 130 ms, PR interval 119 to 210 ms vs. 120 to 202 ms, QRS duration 74 to 110 ms vs. 70 to 104 ms, QT interval 324 to 441 ms vs. 314 and 438 ms, P-wave axis − 29 to 850 vs. -18 to 810, QRS-wave axis − 13 to 850 vs. -180 and 820, T-wave axis 0 to 720 vs. -8 to 730, Sokolow-Lyon index 2.13 to 6.21 mV vs. 1.60 to 4.87 mV, Cornell index 0.17 to 6.24 mV vs. 0.14 mV to 4.35 mV. Conclusions. The values described for the electrocardiographic measurements above can act as a reference framework for Angolan adults without established heart disease. Our study suggests that the normal range of most ECG parameters vary according to age and sex and the ECG diagnostic criteria must therefore be specific for these demographic measures.
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spelling Normal limits of the electrocardiogram in AngolansECG Normal limitsElectrocardiogramCardiologyAngolaHeart function testsElectrodiagnosisIntroduction. Studies on the normal electrocardiogram limits in African populations are limited, especially in sub-Saharan Africa. There is no literature describing normal ECG limits in Angolans. Objectives. The aim of this study is to establish the normal ECG limits for adult Angolans, without established heart disease, stratified by gender and age. Methods. A cross-sectional study was performed, involving 2179 participants from a population in northern Angola, without established heart disease, aged between 15 and 74 years. A 12‑lead ECG and a rhythm strip were recorded for all participants and analysed and processed by the University of Glasgow software and encoded by the Minnesota Code. The normal range of the electrocardiographic parameters were established as the 2nd and 98th percentiles of the measurement distribution per age group and gender. Mann-Whitney and Kruskal-Wallis tests were used for two independent groups and Bonferroni adjustments were used for multiple testing. GAMLSS models were used to obtain the continuous age-dependent percentile curves. Results. The normal range of the ECG differed between men and women: heart rate 49 to 100 bpm vs. 55 to 108 bpm, P wave duration 81 to 130 ms vs. 84 to 130 ms, PR interval 119 to 210 ms vs. 120 to 202 ms, QRS duration 74 to 110 ms vs. 70 to 104 ms, QT interval 324 to 441 ms vs. 314 and 438 ms, P-wave axis − 29 to 850 vs. -18 to 810, QRS-wave axis − 13 to 850 vs. -180 and 820, T-wave axis 0 to 720 vs. -8 to 730, Sokolow-Lyon index 2.13 to 6.21 mV vs. 1.60 to 4.87 mV, Cornell index 0.17 to 6.24 mV vs. 0.14 mV to 4.35 mV. Conclusions. The values described for the electrocardiographic measurements above can act as a reference framework for Angolan adults without established heart disease. Our study suggests that the normal range of most ECG parameters vary according to age and sex and the ECG diagnostic criteria must therefore be specific for these demographic measures.Elsevier20202020-01-01T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttps://hdl.handle.net/10216/143209eng0022-073610.1016/j.jelectrocard.2020.10.011Gonçalves, MAAPedro, JMSilva, CMagalhães, PBrito, Minfo:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-11-29T15:51:07Zoai:repositorio-aberto.up.pt:10216/143209Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-20T00:33:43.116789Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Normal limits of the electrocardiogram in Angolans
title Normal limits of the electrocardiogram in Angolans
spellingShingle Normal limits of the electrocardiogram in Angolans
Gonçalves, MAA
ECG Normal limits
Electrocardiogram
Cardiology
Angola
Heart function tests
Electrodiagnosis
title_short Normal limits of the electrocardiogram in Angolans
title_full Normal limits of the electrocardiogram in Angolans
title_fullStr Normal limits of the electrocardiogram in Angolans
title_full_unstemmed Normal limits of the electrocardiogram in Angolans
title_sort Normal limits of the electrocardiogram in Angolans
author Gonçalves, MAA
author_facet Gonçalves, MAA
Pedro, JM
Silva, C
Magalhães, P
Brito, M
author_role author
author2 Pedro, JM
Silva, C
Magalhães, P
Brito, M
author2_role author
author
author
author
dc.contributor.author.fl_str_mv Gonçalves, MAA
Pedro, JM
Silva, C
Magalhães, P
Brito, M
dc.subject.por.fl_str_mv ECG Normal limits
Electrocardiogram
Cardiology
Angola
Heart function tests
Electrodiagnosis
topic ECG Normal limits
Electrocardiogram
Cardiology
Angola
Heart function tests
Electrodiagnosis
description Introduction. Studies on the normal electrocardiogram limits in African populations are limited, especially in sub-Saharan Africa. There is no literature describing normal ECG limits in Angolans. Objectives. The aim of this study is to establish the normal ECG limits for adult Angolans, without established heart disease, stratified by gender and age. Methods. A cross-sectional study was performed, involving 2179 participants from a population in northern Angola, without established heart disease, aged between 15 and 74 years. A 12‑lead ECG and a rhythm strip were recorded for all participants and analysed and processed by the University of Glasgow software and encoded by the Minnesota Code. The normal range of the electrocardiographic parameters were established as the 2nd and 98th percentiles of the measurement distribution per age group and gender. Mann-Whitney and Kruskal-Wallis tests were used for two independent groups and Bonferroni adjustments were used for multiple testing. GAMLSS models were used to obtain the continuous age-dependent percentile curves. Results. The normal range of the ECG differed between men and women: heart rate 49 to 100 bpm vs. 55 to 108 bpm, P wave duration 81 to 130 ms vs. 84 to 130 ms, PR interval 119 to 210 ms vs. 120 to 202 ms, QRS duration 74 to 110 ms vs. 70 to 104 ms, QT interval 324 to 441 ms vs. 314 and 438 ms, P-wave axis − 29 to 850 vs. -18 to 810, QRS-wave axis − 13 to 850 vs. -180 and 820, T-wave axis 0 to 720 vs. -8 to 730, Sokolow-Lyon index 2.13 to 6.21 mV vs. 1.60 to 4.87 mV, Cornell index 0.17 to 6.24 mV vs. 0.14 mV to 4.35 mV. Conclusions. The values described for the electrocardiographic measurements above can act as a reference framework for Angolan adults without established heart disease. Our study suggests that the normal range of most ECG parameters vary according to age and sex and the ECG diagnostic criteria must therefore be specific for these demographic measures.
publishDate 2020
dc.date.none.fl_str_mv 2020
2020-01-01T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
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status_str publishedVersion
dc.identifier.uri.fl_str_mv https://hdl.handle.net/10216/143209
url https://hdl.handle.net/10216/143209
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv 0022-0736
10.1016/j.jelectrocard.2020.10.011
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dc.publisher.none.fl_str_mv Elsevier
publisher.none.fl_str_mv Elsevier
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