Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical application

Detalhes bibliográficos
Autor(a) principal: Lage, Teresa Cristina Carqueijó
Data de Publicação: 2021
Outros Autores: Rodrigues, Raquel Oliveira, Catarino, Susana Oliveira, Gallo, Juan, Bañobre-López, Manuel, Minas, Graça
Tipo de documento: Artigo
Idioma: eng
Título da fonte: Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
Texto Completo: http://hdl.handle.net/1822/73403
Resumo: The combination of diagnostics and therapy (theranostic) is one of the most complex, yet promising strategies envisioned for nanoengineered multifunctional systems in nanomedicine. From the various multimodal nanosystems proposed, a number of works have established the potential of Graphene-based Magnetic Nanoparticles (GbMNPs) as theranostic platforms. This magnetic nanosystem combines the excellent magnetic performance of magnetic nanoparticles with the unique properties of graphene-based materials, such as large surface area for functionalization, high charge carrier mobility and high chemical and thermal stability. This hybrid nanosystems aims toward a synergistic theranostic effect. Here, we focus on the most recent developments in GbMNPs for theranostic applications. Particular attention is given to the synergistic effect of these composites, as well as to the limitations and possible future directions towards a potential clinical application.
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spelling Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical applicationGrapheneMagnetic nanoparticlesGraphene-based nanomaterialsTheranosticCiências Médicas::Biotecnologia MédicaScience & TechnologySaúde de qualidadeThe combination of diagnostics and therapy (theranostic) is one of the most complex, yet promising strategies envisioned for nanoengineered multifunctional systems in nanomedicine. From the various multimodal nanosystems proposed, a number of works have established the potential of Graphene-based Magnetic Nanoparticles (GbMNPs) as theranostic platforms. This magnetic nanosystem combines the excellent magnetic performance of magnetic nanoparticles with the unique properties of graphene-based materials, such as large surface area for functionalization, high charge carrier mobility and high chemical and thermal stability. This hybrid nanosystems aims toward a synergistic theranostic effect. Here, we focus on the most recent developments in GbMNPs for theranostic applications. Particular attention is given to the synergistic effect of these composites, as well as to the limitations and possible future directions towards a potential clinical application.This work is the result of the project NORTE-01-0145-FEDER-029394, RTChip4Theranostics, and was supported by Programa Operacional Regional do Norte-Norte Portugal Regional Operational Programme (NORTE 2020), under the PORTUGAL 2020 Partnership Agreement through the European Regional Development Fund (FEDER) and by Fundação para a Ciência e Tecnologia (FCT), IP, project reference PTDC/EMD-EMD/29394/2017. The authors also acknowledge the partial financial support by the projects UID/EEA/04436/2020 and by the project NORTE-01-0145-FEDER- 030171.MDPIUniversidade do MinhoLage, Teresa Cristina CarqueijóRodrigues, Raquel OliveiraCatarino, Susana OliveiraGallo, JuanBañobre-López, ManuelMinas, Graça2021-04-222021-04-22T00:00:00Zinfo:eu-repo/semantics/publishedVersioninfo:eu-repo/semantics/articleapplication/pdfhttp://hdl.handle.net/1822/73403engLage, T.; Rodrigues, R.O.; Catarino, S.; Gallo, J.; Bañobre-López, M.; Minas, G. Graphene-Based Magnetic Nanoparticles for Theranostics: An Overview for Their Potential in Clinical Application. Nanomaterials 2021, 11, 1073. https://doi.org/10.3390/nano110510732079-499110.3390/nano11051073https://www.mdpi.com/2079-4991/11/5/1073info:eu-repo/semantics/openAccessreponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãoinstacron:RCAAP2023-07-21T12:40:42Zoai:repositorium.sdum.uminho.pt:1822/73403Portal AgregadorONGhttps://www.rcaap.pt/oai/openaireopendoar:71602024-03-19T19:37:33.188794Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informaçãofalse
dc.title.none.fl_str_mv Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical application
title Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical application
spellingShingle Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical application
Lage, Teresa Cristina Carqueijó
Graphene
Magnetic nanoparticles
Graphene-based nanomaterials
Theranostic
Ciências Médicas::Biotecnologia Médica
Science & Technology
Saúde de qualidade
title_short Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical application
title_full Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical application
title_fullStr Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical application
title_full_unstemmed Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical application
title_sort Graphene-based magnetic nanoparticles for theranostics: an overview for their potential in clinical application
author Lage, Teresa Cristina Carqueijó
author_facet Lage, Teresa Cristina Carqueijó
Rodrigues, Raquel Oliveira
Catarino, Susana Oliveira
Gallo, Juan
Bañobre-López, Manuel
Minas, Graça
author_role author
author2 Rodrigues, Raquel Oliveira
Catarino, Susana Oliveira
Gallo, Juan
Bañobre-López, Manuel
Minas, Graça
author2_role author
author
author
author
author
dc.contributor.none.fl_str_mv Universidade do Minho
dc.contributor.author.fl_str_mv Lage, Teresa Cristina Carqueijó
Rodrigues, Raquel Oliveira
Catarino, Susana Oliveira
Gallo, Juan
Bañobre-López, Manuel
Minas, Graça
dc.subject.por.fl_str_mv Graphene
Magnetic nanoparticles
Graphene-based nanomaterials
Theranostic
Ciências Médicas::Biotecnologia Médica
Science & Technology
Saúde de qualidade
topic Graphene
Magnetic nanoparticles
Graphene-based nanomaterials
Theranostic
Ciências Médicas::Biotecnologia Médica
Science & Technology
Saúde de qualidade
description The combination of diagnostics and therapy (theranostic) is one of the most complex, yet promising strategies envisioned for nanoengineered multifunctional systems in nanomedicine. From the various multimodal nanosystems proposed, a number of works have established the potential of Graphene-based Magnetic Nanoparticles (GbMNPs) as theranostic platforms. This magnetic nanosystem combines the excellent magnetic performance of magnetic nanoparticles with the unique properties of graphene-based materials, such as large surface area for functionalization, high charge carrier mobility and high chemical and thermal stability. This hybrid nanosystems aims toward a synergistic theranostic effect. Here, we focus on the most recent developments in GbMNPs for theranostic applications. Particular attention is given to the synergistic effect of these composites, as well as to the limitations and possible future directions towards a potential clinical application.
publishDate 2021
dc.date.none.fl_str_mv 2021-04-22
2021-04-22T00:00:00Z
dc.type.status.fl_str_mv info:eu-repo/semantics/publishedVersion
dc.type.driver.fl_str_mv info:eu-repo/semantics/article
format article
status_str publishedVersion
dc.identifier.uri.fl_str_mv http://hdl.handle.net/1822/73403
url http://hdl.handle.net/1822/73403
dc.language.iso.fl_str_mv eng
language eng
dc.relation.none.fl_str_mv Lage, T.; Rodrigues, R.O.; Catarino, S.; Gallo, J.; Bañobre-López, M.; Minas, G. Graphene-Based Magnetic Nanoparticles for Theranostics: An Overview for Their Potential in Clinical Application. Nanomaterials 2021, 11, 1073. https://doi.org/10.3390/nano11051073
2079-4991
10.3390/nano11051073
https://www.mdpi.com/2079-4991/11/5/1073
dc.rights.driver.fl_str_mv info:eu-repo/semantics/openAccess
eu_rights_str_mv openAccess
dc.format.none.fl_str_mv application/pdf
dc.publisher.none.fl_str_mv MDPI
publisher.none.fl_str_mv MDPI
dc.source.none.fl_str_mv reponame:Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
instname:Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron:RCAAP
instname_str Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
instacron_str RCAAP
institution RCAAP
reponame_str Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
collection Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos)
repository.name.fl_str_mv Repositório Científico de Acesso Aberto de Portugal (Repositórios Cientìficos) - Agência para a Sociedade do Conhecimento (UMIC) - FCT - Sociedade da Informação
repository.mail.fl_str_mv
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